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Potensi Ekstrak Etanol Kulit Batang Jabon (Anthocephalus cadamba (Roxb) Miq.) Sebagai Antiinflamasi

JURNAL BIOLOGI PAPUA · Vol. 16 No. 1 (2024) · pp. 20–26

DOI
10.31957/jbp.3362
ISSN
2503-0450, 2086-3314
Published
2024-04-05
Publisher
Jurusan Biologi FMIPA Universitas Cenderawasih
Language
eng

Abstract

This study investigates the anti-inflammatory properties of an ethanol extract from Jabon plant stem bark in male mice using the Rat Hind Paw Edema method. Twenty-five male mice were divided into five groups: negative control (Na-CMC 1%), positive control (mefenamic acid), and three groups receiving the extract at doses of 50 mg/kg, 100 mg/kg, and 200 mg/kg. Measurements were taken every 30 minutes for three hours using a plethysmometer. Analysis with one-way ANOVA and Duncan's test revealed significant anti-inflammatory effects for all doses, with the most effective being 100 mg/kg, showing 93.42% inhibition. The results suggest Jabon plant extract as a promising anti-inflammatory agent.

Keywords

Collaboration network of the authors

40 authors · 144 co-authorship links · showing the 40 most connected

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Co-authorOrganisationJoint articles
Rani D. PratiwiAffiliation unknown4
Rusnaeni RusnaeniAffiliation unknown3
Felycitae E. AppaAffiliation unknown3
Mustika E. PratiwiAffiliation unknown2
Eva Susanty SimaremareAffiliation unknown2
Septriyanto DirgantaraAffiliation unknown2
Rani Dewi PratiwiAffiliation unknown2
Deshinta S. NataliaAffiliation unknown1
Eva S. SimaremareAffiliation unknown1
Verena AgustiniAffiliation unknown1
Jane AwomAffiliation unknown1
Susan WopiAffiliation unknown1
Noviana HallikAffiliation unknown1
Ega RianaAffiliation unknown1
Nur F. BakrieAffiliation unknown1
Risma PayungAffiliation unknown1
Aris A.L. ToruanAffiliation unknown1
Maria J.S OlaAffiliation unknown1
Claudius H.B. TobiAffiliation unknown1
Kevry SupraptiAffiliation unknown1
Andre A. BarusAffiliation unknown1
Artha M. SimanjuntakAffiliation unknown1
Agatha C.I. JedautAffiliation unknown1
Napita P.C. PasaribuAffiliation unknown1
Allowisya FutwembunAffiliation unknown1
Khoirul HudaAffiliation unknown1
Qonita A. NisaAffiliation unknown1
Andre M. WorabaiAffiliation unknown1
Dimas A. SyafrudinAffiliation unknown1
Fadil M. Al RidhaAffiliation unknown1
Karlin MansumberAffiliation unknown1
Kristina I. RahailAffiliation unknown1
Marselina E. KotenAffiliation unknown1
Muhammad M. KhalilAffiliation unknown1
Ota M. RumainumAffiliation unknown1
Pitera WendaAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ejournal.uncen.ac.id/index.php/JBP/oai, first harvested 1 Nov 2026, last seen 1 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Potensi Ekstrak Etanol Kulit Batang Jabon (Anthocephalus cadamba (Roxb) Miq.) Sebagai Antiinflamasi</dc:title>
	<dc:creator>Bakri, Nur F.</dc:creator>
	<dc:creator>Rusnaeni</dc:creator>
	<dc:creator>Sasarari, Sarce M.</dc:creator>
	<dc:creator>Gunawan, Elsye</dc:creator>
	<dc:subject xml:lang="en-US">antiinflammation </dc:subject>
	<dc:subject xml:lang="en-US">ethanol extract</dc:subject>
	<dc:subject xml:lang="en-US">Jabon</dc:subject>
	<dc:subject xml:lang="en-US">stem bark</dc:subject>
	<dc:description xml:lang="en-US">This study investigates the anti-inflammatory properties of an ethanol extract from Jabon plant stem bark in male mice using the Rat Hind Paw Edema method. Twenty-five male mice were divided into five groups: negative control (Na-CMC 1%), positive control (mefenamic acid), and three groups receiving the extract at doses of 50 mg/kg, 100 mg/kg, and 200 mg/kg. Measurements were taken every 30 minutes for three hours using a plethysmometer. Analysis with one-way ANOVA and Duncan's test revealed significant anti-inflammatory effects for all doses, with the most effective being 100 mg/kg, showing 93.42% inhibition. The results suggest Jabon plant extract as a promising anti-inflammatory agent.</dc:description>
	<dc:publisher xml:lang="en-US">Jurusan Biologi FMIPA Universitas Cenderawasih</dc:publisher>
	<dc:date>2024-04-05</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ejournal.uncen.ac.id/index.php/JBP/article/view/3362</dc:identifier>
	<dc:identifier>10.31957/jbp.3362</dc:identifier>
	<dc:source xml:lang="en-US">JURNAL BIOLOGI PAPUA; Vol. 16 No. 1 (2024); 20-26</dc:source>
	<dc:source xml:lang="id-ID">Jurnal Biologi Papua; Vol 16 No 1 (2024); 20-26</dc:source>
	<dc:source>2503-0450</dc:source>
	<dc:source>2086-3314</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ejournal.uncen.ac.id/index.php/JBP/article/view/3362/2696</dc:relation>
</oai_dc:dc>