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ANALYSIS OF THE ABILITY OF NANO ETHANOL EXTRACT OF CORIANDER (Coriandrum sativum L.) SEEDS TO REDUCE BLOOD GLUCOSE LEVELS IN HYPERGLYCEMIC WISTAR RATS

Jurnal Ilmu Pendidikan Indonesia · Vol. 11 No. 2 (2023) · pp. 81–92

DOI
10.31957/jipi.v11i2.3076
ISSN
2623-226X, 2338-3402
Published
2023-06-27
Publisher
Master of Science Education Program, Postgraduate Program of Cenderawasih University
Language
eng

Abstract

Nano ethanol extract of coriander seeds is proven to increase the activity of active compounds in the body. This research was conducted to see the ability of coriander seed ethanol extract to reduce glucose levels in hyperglycemic rats compared to coriander seed extract without nano. The size of the nano coriander seed extract after being characterized by the Particle Size Analyzer (PSA) was 182.4 nm and the zeta potential value was -1.5 mV. The activity test results showed the ability of the coriander seed ethanol extract to be more effective in lowering blood glucose levels compared to the coriander seed extract without nano. Identification of compounds thought to be effective as hypoglycemics using Liquid Chromatography-Mass Spectrometry/Mass Spectrometry (LC-MS/MS), identified 7 compounds namely phenylalanine, indole, apigenin, 4-methoxybenzaldehyde, 2,5-dimethoxybenzaldehyde, 2-flouren-9-ylidenemethyl-pyridine, and 5-pentyl-1,3-benzenediol, which are suspected to be active as hypoglycemics are phenylalanine, indole, apigenin, and 2,5-dimethoxybenzaldehyde. The ethanol extract of coriander seeds in nanoparticle preparations is more effective in reducing blood glucose levels than the ethanol extract of coriander seeds without nano preparations

Keywords

Collaboration network of the authors

12 authors · 19 co-authorship links · 2 across different organisations

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  • IPB University
  • Institut Teknologi Telkom Purwokerto
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Rendy Eka SaputraIPB University1
Yani NurhadryaniIPB University1
Ariq Cahya WardhanaInstitut Teknologi Telkom Purwokerto1
Eliyah Acantha ManapaIPB University1
Shelvie Nidya NeymanIPB University1
Nila Susila YuliantiIPB University1
Kudang Boro SeminarIPB University1
Joko HermaniantoIPB University1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ejournal.uncen.ac.id/index.php/JIPI/oai, first harvested 1 Nov 2026, last seen 1 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">ANALYSIS OF THE ABILITY OF NANO ETHANOL EXTRACT OF CORIANDER (Coriandrum sativum L.) SEEDS TO REDUCE BLOOD GLUCOSE LEVELS IN HYPERGLYCEMIC WISTAR RATS</dc:title>
	<dc:creator>Wahjuni, Sri</dc:creator>
	<dc:creator>Parwata, I M.O. Adi</dc:creator>
	<dc:creator>Putra, A.A. Bawa</dc:creator>
	<dc:creator>Lahaya, Mustika</dc:creator>
	<dc:subject xml:lang="en-US">Coriander Seeds</dc:subject>
	<dc:subject xml:lang="en-US">Hyperglycemic</dc:subject>
	<dc:subject xml:lang="en-US">Nano Coriander Seed Ethanol Extract</dc:subject>
	<dc:description xml:lang="en-US">Nano ethanol extract of coriander seeds is proven to increase the activity of active compounds in the body. This research was conducted to see the ability of coriander seed ethanol extract to reduce glucose levels in hyperglycemic rats compared to coriander seed extract without nano. The size of the nano coriander seed extract after being characterized by the Particle Size Analyzer (PSA) was 182.4 nm and the zeta potential value was -1.5 mV. The activity test results showed the ability of the coriander seed ethanol extract to be more effective in lowering blood glucose levels compared to the coriander seed extract without nano. Identification of compounds thought to be effective as hypoglycemics using Liquid Chromatography-Mass Spectrometry/Mass Spectrometry (LC-MS/MS), identified 7 compounds namely phenylalanine, indole, apigenin, 4-methoxybenzaldehyde, 2,5-dimethoxybenzaldehyde, 2-flouren-9-ylidenemethyl-pyridine , and 5-pentyl-1,3-benzenediol, which are suspected to be active as hypoglycemics are phenylalanine, indole, apigenin, and 2,5-dimethoxybenzaldehyde. The ethanol extract of coriander seeds in nanoparticle preparations is more effective in reducing blood glucose levels than the ethanol extract of coriander seeds without nano preparations</dc:description>
	<dc:publisher xml:lang="en-US">Master of Science Education Program, Postgraduate Program of Cenderawasih University</dc:publisher>
	<dc:date>2023-06-27</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ejournal.uncen.ac.id/index.php/JIPI/article/view/3076</dc:identifier>
	<dc:identifier>10.31957/jipi.v11i2.3076</dc:identifier>
	<dc:source xml:lang="en-US">Jurnal Ilmu Pendidikan Indonesia; Vol. 11 No. 2 (2023): JURNAL ILMU PENDIDIKAN INDONSIA; 81-92</dc:source>
	<dc:source xml:lang="id-ID">Jurnal Ilmu Pendidikan Indonesia; Vol 11 No 2 (2023): JURNAL ILMU PENDIDIKAN INDONSIA; 81-92</dc:source>
	<dc:source>2623-226X</dc:source>
	<dc:source>2338-3402</dc:source>
	<dc:source>10.31957/jipi.v11i2</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ejournal.uncen.ac.id/index.php/JIPI/article/view/3076/2341</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2023 Jurnal Ilmu Pendidikan Indonesia</dc:rights>
</oai_dc:dc>