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DETERMINANTS OF PRE-EXPOSURE PROPHYLAXIS (PREP) ADHERENCE AMONG MEN WHO HAVE SEX WITH MEN AT JUMPANDANG BARU PRIMARY HEALTHCARE CENTER: A CROSS-SECTIONAL STUDY

Hasanuddin Journal of Public Health (HJPH) · Vol. 7 No. 3 (2026) · pp. 339–353

DOI
10.30597/hjph.v7i3.44019
ISSN
2721-2408
Published
2026-10-22
Publisher
Faculty of Public Health, Hasanuddin University, Makassar
Language
en
License
creativecommons.org/licenses/by-sa/4.0/

Abstract

Background: Globally, HIV transmission occurs predominantly through heterosexual contact, particularly in sub-Saharan Africa. However, men who have sex with men (MSM) remain a key population with a high burden of HIV infection, including in Indonesia. Pre-exposure prophylaxis (PrEP) has been introduced as an effective strategy for preventing sexually acquired HIV. Its effectiveness depends largely on adherence to the prescribed regimen. Purpose: This study aimed to analyze factors associated with PrEP adherence among MSM at Jumpandang Baru Primary Healthcare Center (Puskesmas Jumpandang Baru). Methods: This quantitative study employed a cross-sectional design. The variables examined included age, educational level, occupation, knowledge, attitude, stigma, social support, and self-efficacy. A total of 130 participants were recruited using accidental sampling, and data were collected through questionnaires. Data were analyzed using Stata, with Pearson’s chi-square test and Fisher’s exact test, as appropriate. Results: Of the 130 respondents, 79 (60.8%) were adherent to PrEP. Occupation (p = 0.008), knowledge (p = 0.008), stigma (p = 0.001), social support (p = 0.001), and self-efficacy (p < 0.001) were significantly associated with PrEP adherence among MSM. Conclusion: Occupation, knowledge, stigma, social support, and self-efficacy were significantly associated with PrEP adherence among MSM at Puskesmas Jumpandang Baru. MSM are encouraged to maintain adherence and communicate regularly with healthcare providers regarding PrEP use. Community health centers should strengthen educational interventions to improve understanding of PrEP and support adherence.

Keywords

Collaboration network of the authors

24 authors · 39 co-authorship links

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  • Universitas Halu Oleo
  • Affiliation unknown
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Co-authorOrganisationJoint articles
Wahiduddin WahiduddinAffiliation unknown3
Indra DwinataAffiliation unknown2
Bakri YusufUniversitas Halu Oleo1
Bahtiar BahtiarUniversitas Halu Oleo1
Hasriany AminUniversitas Halu Oleo1
Rivi HandayaniUniversitas Halu Oleo1
Cecep IbrahimUniversitas Halu Oleo1
Kartini KartiniAffiliation unknown1
Nadhirah NaguAffiliation unknown1
Ansariadi AnsariadiAffiliation unknown1
Alifah Nurjannah TriputriAffiliation unknown1
Sri HartinaAffiliation unknown1
Nurkhalisah HarisAffiliation unknown1
Muh. Arman NyombaAffiliation unknown1
Fitrie Ramadhani ReskiAffiliation unknown1
Ridwan AmiruddinAffiliation unknown1
Alfrida SandaAffiliation unknown1
Lilmawati LilmawatiAffiliation unknown1
Andi Arsunan ArsinAffiliation unknown1
Auwlya Zhafitry HarisAffiliation unknown1
Nur Nasry NoorAffiliation unknown1
Firda Nurul Fadilah FaridAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/hjph/oai, first harvested 2 Nov 2026, last seen 2 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en">DETERMINANTS OF PRE-EXPOSURE PROPHYLAXIS (PREP) ADHERENCE AMONG MEN WHO HAVE SEX WITH MEN AT JUMPANDANG BARU PRIMARY HEALTHCARE CENTER: A CROSS-SECTIONAL STUDY</dc:title>
	<dc:creator xml:lang="en">Arsyam, Nur Inayah Dwiyull Kasbayl</dc:creator>
	<dc:creator xml:lang="en">Rismayanti, Rismayanti</dc:creator>
	<dc:creator xml:lang="id">Arsyam, Nur Inayah Dwiyull Kasbayl</dc:creator>
	<dc:subject xml:lang="en">HIV;</dc:subject>
	<dc:subject xml:lang="en">adherence;</dc:subject>
	<dc:subject xml:lang="en">MSM;</dc:subject>
	<dc:subject xml:lang="en">PrEP;</dc:subject>
	<dc:description xml:lang="en">Background: Globally, HIV transmission occurs predominantly through heterosexual contact, particularly in sub-Saharan Africa. However, men who have sex with men (MSM) remain a key population with a high burden of HIV infection, including in Indonesia. Pre-exposure prophylaxis (PrEP) has been introduced as an effective strategy for preventing sexually acquired HIV. Its effectiveness depends largely on adherence to the prescribed regimen. Purpose: This study aimed to analyze factors associated with PrEP adherence among MSM at Jumpandang Baru Primary Healthcare Center (Puskesmas Jumpandang Baru). Methods: This quantitative study employed a cross-sectional design. The variables examined included age, educational level, occupation, knowledge, attitude, stigma, social support, and self-efficacy. A total of 130 participants were recruited using accidental sampling, and data were collected through questionnaires. Data were analyzed using Stata, with Pearson’s chi-square test and Fisher’s exact test, as appropriate. Results: Of the 130 respondents, 79 (60.8%) were adherent to PrEP. Occupation (p = 0.008), knowledge (p = 0.008), stigma (p = 0.001), social support (p = 0.001), and self-efficacy (p &amp;lt; 0.001) were significantly associated with PrEP adherence among MSM. Conclusion: Occupation, knowledge, stigma, social support, and self-efficacy were significantly associated with PrEP adherence among MSM at Puskesmas Jumpandang Baru. MSM are encouraged to maintain adherence and communicate regularly with healthcare providers regarding PrEP use. Community health centers should strengthen educational interventions to improve understanding of PrEP and support adherence.</dc:description>
	<dc:publisher xml:lang="en">Faculty of Public Health, Hasanuddin University, Makassar</dc:publisher>
	<dc:date>2026-10-22</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/hjph/article/view/44019</dc:identifier>
	<dc:identifier>10.30597/hjph.v7i3.44019</dc:identifier>
	<dc:source xml:lang="en">Hasanuddin Journal of Public Health (HJPH); Vol. 7 No. 3: OCTOBER 2026; 339-353</dc:source>
	<dc:source>2721-2408</dc:source>
	<dc:source>10.30597/hjph.v7i3</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/hjph/article/view/44019/15160</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2026 by author</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by-sa/4.0/</dc:rights>
</oai_dc:dc>