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A Preliminary Study of Bioactivity and Identification of Secondary Metabolite Functional Groups in Extracts of Agelas nakamurai Hoshino Sponge from Spermonde Archipelago, Indonesia

Marina Chimica Acta · Vol. 14 No. 2 (2013)

ISSN
1411-2132
Published
2013-10-01
Publisher
Hasanuddin University
Language
en

Abstract

Uji pendahuluan bioaktivitas dan identifikasi gugus fungsi metabolit sekunder ekstrak dalam metanol, n-heksan and metilen klorida dari spons Agelas nakamurai Hoshino, asal pulau Kapoposang, kepulauan Spermonde telah dilakukan. Juga test bioaktivitas dilakukan menggunakan Artemia salina (LC50) untuk mendapatkan konsentrasi letalnya. Hasilnya LC50 adalah 187.932 ppm yang menunjukkan potensi ekstrak sebagai obat anti kanker. Identifikasi komponen dengan reagensia spesifik seperti Lieberman- Burchard, Mayer, Wagner, Dragendorff dan Salkowski ditambah hasil analisis FTIR menunjukkan kandungan komponen ekstrak seperti alkaloid, steroid and terpenoid. Karakteristik pita serapan alkaloid adalah for alkaloid adalah stretching NH at 3600 to 3400 cm-1 dan stretching pendukung C-N at 1250 to 1930 cm-1. Komponen spesifik untuk Agelas nakamurai adalah substitusi bromo dalam alkaloid yang ditandai oleh munculnya pita serapan C-Br medium pada 760 to 745 cm-1.

Collaboration network of the authors

40 authors · 100 co-authorship links · showing the 40 most connected

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  • Tadulako University
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Maming GaffarAffiliation unknown14
Muhammad ZakirAffiliation unknown11
Ahyar AhmadAffiliation unknown9
Tjodi HarlimAffiliation unknown7
Maming MamingAffiliation unknown6
Muhammad LukmanAffiliation unknown5
Nursiah La NafieAffiliation unknown4
Nicole de VoogdAffiliation unknown4
Lydia MelawatyAffiliation unknown3
Rakhmad ArmusAffiliation unknown3
Paulina TabaAffiliation unknown2
Ismail MarzukiAffiliation unknown2
Waode RustiahAffiliation unknown2
Asma AssaAffiliation unknown2
Hafiludin UliAffiliation unknown2
Fredryk Welliam MandeyAffiliation unknown2
Firdaus FirdausAffiliation unknown2
Saefuddin .Affiliation unknown1
Ahmad ZainiAffiliation unknown1
ZarlinaAffiliation unknown1
Ahmad FaizalAffiliation unknown1
Shinta WerorilangiAffiliation unknown1
Akbar TahirAffiliation unknown1
M. Farid SamawiAffiliation unknown1
Waode Nur RahmaniahAffiliation unknown1
Rahmawati RahmawatiAffiliation unknown1
M Natsir DjideAffiliation unknown1
Febby KurniatyAffiliation unknown1
Anita Nur RamadhaniAffiliation unknown1
Rahmawati RahmawatiAffiliation unknown1
Suhaela SuhaelaTadulako University1
Usman UsmanAffiliation unknown1
Sukmawati SukmawatiAffiliation unknown1
Firdaus ZentaAffiliation unknown1
Musa RamangAffiliation unknown1
Gita Permata SariAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/mca/oai, first harvested 5 Nov 2026, last seen 5 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en">A Preliminary Study of Bioactivity and Identification of Secondary Metabolite Functional Groups in Extracts of Agelas nakamurai Hoshino Sponge from Spermonde Archipelago, Indonesia</dc:title>
	<dc:creator xml:lang="en">Sapar, Ajuk</dc:creator>
	<dc:creator xml:lang="en">Noor, Alfian</dc:creator>
	<dc:creator xml:lang="en">Soekamto, Nunuk Hariani</dc:creator>
	<dc:creator xml:lang="en">Hadi, Tri Aryono</dc:creator>
	<dc:description xml:lang="en">Uji pendahuluan bioaktivitas dan identifikasi gugus fungsi metabolit sekunder ekstrak dalam metanol, n-heksan and metilen klorida dari spons Agelas nakamurai Hoshino, asal pulau Kapoposang, kepulauan Spermonde telah dilakukan. Juga test bioaktivitas dilakukan menggunakan Artemia salina (LC50) untuk mendapatkan  konsentrasi letalnya.  Hasilnya  LC50  adalah 187.932  ppm   yang  menunjukkan potensi ekstrak sebagai obat anti kanker. Identifikasi komponen dengan reagensia spesifik seperti Lieberman- Burchard, Mayer, Wagner, Dragendorff dan Salkowski ditambah hasil analisis FTIR menunjukkan kandungan komponen ekstrak seperti alkaloid, steroid and terpenoid. Karakteristik pita serapan alkaloid adalah for alkaloid adalah stretching NH at 3600 to 3400 cm-1 dan stretching pendukung C-N at 1250 to 1930 cm-1. Komponen spesifik untuk Agelas nakamurai adalah substitusi bromo dalam alkaloid yang ditandai oleh munculnya pita serapan  C-Br medium pada 760 to 745 cm-1.</dc:description>
	<dc:publisher xml:lang="en">Hasanuddin University</dc:publisher>
	<dc:date>2013-10-01</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
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	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/mca/article/view/971</dc:identifier>
	<dc:source xml:lang="en">Marina Chimica Acta; Vol. 14 No. 2 (2013): Volume 14 No. 2 (2013)</dc:source>
	<dc:source>1411-2132</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/mca/article/view/971/616</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2016 Marina Chimica Acta</dc:rights>
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