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ANTIOXIDANT ACTIVITY AND TOXICITY POLYSACCHARIDE EXTRACT FROM RED ALGAE Eucheuma cottonii AND Eucheuma spinosum

Marina Chimica Acta · Vol. 17 No. 2 (2016)

ISSN
1411-2132
Published
2016-10-31
Publisher
Hasanuddin University
Language
en

Abstract

Red algae Eucheuma cottonii and Eucheuma spinosum which one alternative source of antioxidant and anticancer because contains polysaccharide compound. This research aims to isolate and examine the activity of antioxidant and toxicity polysaccharide extract from red algae Eucheuma cottonii and Eucheuma spinosum. The study was carried out by isolating the polysaccharide extract using water and methanol-ethanol precipitation. Antioxidant activity of crude extract was examined using 1,1-Difenil-2-pikrilhidrazil (DPPH) method, and toxicity test was carried out using Brine Shrimp Lethality Test (BSLT). The research results showed that the crude extract polysaccharide for Eucheuma cottonii and Eucheuma spinosum have strong antioxidant activity with IC50 value of 72,49 ppm and 75,98 ppm. The result of BSLT assay showed that the crude extract polysaccharide has a highest toxicity with LC50 value of 165,88 ppm and 337,21 ppm there are classified as toxic. The crude extract polysaccharide Eucheuma cottonii and Eucheuma spinosum has a potential to be developed as an alternative antioxidant and anticancer agent.

Collaboration network of the authors

40 authors · 98 co-authorship links · showing the 40 most connected

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  • Tadulako University
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Seniwati DaliAffiliation unknown9
Alfian NoorAffiliation unknown6
Abdur Rahman ArifAffiliation unknown3
Muhammad LukmanAffiliation unknown3
Rakhmad ArmusAffiliation unknown3
Hanapi UsmanAffiliation unknown3
Sartika DanialAffiliation unknown2
Muh. Nasrum MassiAffiliation unknown2
Rugaiyah A ArfahAffiliation unknown1
Muhammad ZakirAffiliation unknown1
St Fauziah St FauziahAffiliation unknown1
Prastawa BudiAffiliation unknown1
Baharuddin PatandjengiAffiliation unknown1
Tutik KuswinantiAffiliation unknown1
Irene BrugmanAffiliation unknown1
Nurmujahidin NurmujahidinAffiliation unknown1
Ischaidar IschaidarAffiliation unknown1
Suhaela SuhaelaTadulako University1
Indah RayaAffiliation unknown1
Erna MayasariAffiliation unknown1
Ajuk SaparAffiliation unknown1
Nunuk Hariani SoekamtoAffiliation unknown1
Tri Aryono HadiAffiliation unknown1
Mahdalia MahmudAffiliation unknown1
Eva JohannesAffiliation unknown1
Nur UmrianiAffiliation unknown1
Abdul Rauf PatongAffiliation unknown1
Paulina TabaAffiliation unknown1
Fatahu FatahuAffiliation unknown1
Firdaus FirdausAffiliation unknown1
Nunuk Hariani SoekamtoAffiliation unknown1
Selfi WullurAffiliation unknown1
Leliani LelianiAffiliation unknown1
Leliani RamliAffiliation unknown1
Mashuni MashuniAffiliation unknown1
Abdul Wahid WahabAffiliation unknown1
Muhammad SyahrulAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/mca/oai, first harvested 5 Nov 2026, last seen 5 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en">ANTIOXIDANT ACTIVITY AND TOXICITY POLYSACCHARIDE EXTRACT FROM RED ALGAE Eucheuma cottonii AND Eucheuma spinosum</dc:title>
	<dc:creator xml:lang="en">Muawanah, Muawanah</dc:creator>
	<dc:creator xml:lang="en">Ahmad, Ahyar</dc:creator>
	<dc:creator xml:lang="en">Natsir, Hasnah</dc:creator>
	<dc:description xml:lang="en">Red algae Eucheuma cottonii and Eucheuma spinosum which one alternative source of antioxidant and anticancer because contains polysaccharide compound. This research aims to isolate and examine the activity of antioxidant and toxicity polysaccharide extract from red algae Eucheuma cottonii and Eucheuma spinosum . The study was carried out by isolating the polysaccharide extract using water and methanol-ethanol precipitation. Antioxidant activity of crude extract was examined using 1,1-Difenil-2-pikrilhidrazil (DPPH) method, and toxicity test was carried out using Brine Shrimp Lethality Test (BSLT). The research results showed that the crude extract polysaccharide for Eucheuma cottonii and Eucheuma spinosum have strong antioxidant activity with IC50 value of 72,49 ppm and 75,98 ppm. The result of BSLT assay showed that the crude extract polysaccharide has a highest toxicity with LC50 value of 165,88 ppm and 337,21 ppm there are classified as toxic. The crude extract polysaccharide Eucheuma cottonii and Eucheuma spinosum has a potential to be developed as an alternative antioxidant and anticancer agent.</dc:description>
	<dc:publisher xml:lang="en">Hasanuddin University</dc:publisher>
	<dc:date>2016-10-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/mca/article/view/1123</dc:identifier>
	<dc:source xml:lang="en">Marina Chimica Acta; Vol. 17 No. 2 (2016): Volume 17 No. 2 (2016)</dc:source>
	<dc:source>1411-2132</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/mca/article/view/1123/691</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2016 Marina Chimica Acta</dc:rights>
</oai_dc:dc>