Melola Discovery

← Melola Discovery

Akses terbuka Jurnal

Skin Brightening Effects of Ascorbic Acid with ACTISOLV™ Integration: A Longitudinal Analysis Using Repeated Measures ANOVA

Jurnal Matematika, Statistika dan Komputasi · Vol. 22 No. 2 (2026) · hlm. 395–406

DOI
10.20956/j.v22i2.47838
ISSN
2614-8811, 1858-1382
Terbit
2026-01-10
Penerbit
Department of Mathematics, Hasanuddin University
Bahasa
en
Lisensi
creativecommons.org/licenses/by/4.0

Abstrak

Ascorbic Acid is a well-established active ingredient recognized for its efficacy in skin brightening and its antioxidant properties. However, its low chemical stability in cosmetic formulations remains a significant limitation. In response to this challenge, the patent-pending ACTISOLV™ formulation technology has been developed to enhance the stability of Ascorbic Acid, improving its resistance to oxidation and effectiveness in inhibiting melanin production. This study contributes to the advancement of sustainable cosmetic science through the development of more stable, eco-friendly, and sustainable skincare products. This study aimed to evaluate the longitudinal effects of a cream containing 20% Ascorbic Acid formulated with ACTISOLV™ on skin brightness. This study used longitudinal experimental data analyzed by Repeated Measures ANOVA. The results demonstrated a statistically significant increase in skin brightness over time (p-value = 0.000 < 0.05). Posthoc analysis revealed that skin brightness at weeks 6 and 12 differed significantly from baseline. However, no significant difference was found between the control and treatment groups and no significant interaction was observed between time and treatment group. These findings suggest that the observed improvement in skin brightness occurred similarly in both groups, indicating no additional effect attributable to the test formulation.

Kata kunci

Jaringan kolaborasi para penulis

40 penulis · 128 tautan kepenulisan bersama · menampilkan 40 yang paling banyak terhubung

Arahkan kursor atau ketuk sebuah nama untuk menyorot rekan penulisnya. Klik dua kali untuk membuka halaman penulis.

  • Universitas Airlangga
  • Afiliasi tidak diketahui
  • Organisasi berbeda
  • Organisasi sama
  • Afiliasi tidak diketahui
  • Garis lebih tebal = lebih banyak artikel bersama · lingkaran lebih besar = lebih banyak artikel
Tampilkan sebagai tabel
Rekan penulisOrganisasiArtikel bersama
Suliyanto SuliyantoUniversitas Airlangga5
Elly AnaUniversitas Airlangga3
Anisah Nabilah GhasaniUniversitas Airlangga3
Nur ChamidahUniversitas Airlangga2
Ardi KurniawanUniversitas Airlangga2
Sediono SedionoUniversitas Airlangga2
Najwa Khoir AldawiyahUniversitas Airlangga2
Berliani LarasatiUniversitas Airlangga1
Qumadha Zaenal AbidinAfiliasi tidak diketahui1
Juan Krisfigo PrasetyoUniversitas Airlangga1
Alma Khalisa RahmaUniversitas Airlangga1
Steven SoewignjoUniversitas Airlangga1
Ni Wayan Widya Septia SariUniversitas Airlangga1
Andini Putri MedianiUniversitas Airlangga1
M. Aqil Zaidan KamilUniversitas Airlangga1
Rosidun Nindyo PratiwiUniversitas Airlangga1
Nathania FauziahUniversitas Airlangga1
Bimo Okta SyahputraUniversitas Airlangga1
Ahmad Wahyu FirmandaUniversitas Airlangga1
Galuh Cahya NugrahaUniversitas Airlangga1
Billy Christandy SuyonoUniversitas Airlangga1
Idrus SyahzaqiUniversitas Airlangga1
Muhammad Rosyid Ridho Az ZuhroUniversitas Airlangga1
Tentri Ryan RahmanitaUniversitas Airlangga1
Kimberly Maserati SiagianUniversitas Airlangga1
Nadinta Kasih AmaliaUniversitas Airlangga1
Nadya Lovita Hana TrisaUniversitas Airlangga1
Gabriella Agnes BudijonoUniversitas Airlangga1
Rere Fetri DamanikUniversitas Airlangga1
Azizah Atsariyyah ZhafiraUniversitas Airlangga1
Azzah Nazhifa Wina RamadhaniAfiliasi tidak diketahui1
Aulia RamadhantiAfiliasi tidak diketahui1
M. Nabil SaputraUniversitas Airlangga1

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/jmsk/oai, pertama di-harvest 5 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Skin Brightening Effects of Ascorbic Acid with ACTISOLV™ Integration: A Longitudinal Analysis Using Repeated Measures ANOVA</dc:title>
	<dc:creator xml:lang="en">Amelia, Dita</dc:creator>
	<dc:creator xml:lang="en">Suliyanto, Suliyanto</dc:creator>
	<dc:creator xml:lang="en">Mahadesyawardani, Arinda</dc:creator>
	<dc:creator xml:lang="en">Azizah, Nur</dc:creator>
	<dc:creator xml:lang="en">Ariyawan, Jovansha</dc:creator>
	<dc:creator xml:lang="en">Adiputra, R. Arya Januarta</dc:creator>
	<dc:creator xml:lang="en">Adyatma, Irsyad Yoga</dc:creator>
	<dc:subject xml:lang="en">Ascorbic Acid</dc:subject>
	<dc:subject xml:lang="en">Longitudinal Data</dc:subject>
	<dc:subject xml:lang="en">Repeated Measures ANOVA</dc:subject>
	<dc:subject xml:lang="en">Skin Brightening</dc:subject>
	<dc:description xml:lang="en">Ascorbic Acid is a well-established active ingredient recognized for its efficacy in skin brightening and its antioxidant properties. However, its low chemical stability in cosmetic formulations remains a significant limitation. In response to this challenge, the patent-pending ACTISOLV™ formulation technology has been developed to enhance the stability of Ascorbic Acid, improving its resistance to oxidation and effectiveness in inhibiting melanin production. This study contributes to the advancement of sustainable cosmetic science through the development of more stable, eco-friendly, and sustainable skincare products. This study aimed to evaluate the longitudinal effects of a cream containing 20% Ascorbic Acid formulated with ACTISOLV™ on skin brightness. This study used longitudinal experimental data analyzed by Repeated Measures ANOVA. The results demonstrated a statistically significant increase in skin brightness over time (p-value = 0.000 &amp;lt; 0.05). Posthoc analysis revealed that skin brightness at weeks 6 and 12 differed significantly from baseline. However, no significant difference was found between the control and treatment groups and no significant interaction was observed between time and treatment group. These findings suggest that the observed improvement in skin brightness occurred similarly in both groups, indicating no additional effect attributable to the test formulation.</dc:description>
	<dc:publisher xml:lang="en">Department of Mathematics, Hasanuddin University</dc:publisher>
	<dc:date>2026-01-10</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/jmsk/article/view/47838</dc:identifier>
	<dc:identifier>10.20956/j.v22i2.47838</dc:identifier>
	<dc:source xml:lang="en">Jurnal Matematika, Statistika dan Komputasi; Vol. 22 No. 2 (2026): JANUARY 2026; 395-406</dc:source>
	<dc:source>2614-8811</dc:source>
	<dc:source>1858-1382</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/jmsk/article/view/47838/13992</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2026 Jurnal Matematika, Statistika dan Komputasi</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by/4.0</dc:rights>
</oai_dc:dc>