Melola Discovery

← Melola Discovery

Jurnal

Characterization of Compounds From Extract of Leaf Cloroform Melochia umbellata (Houtt.) Stapf var. Degrabrata K. and Test Antihiperglicemic Activities

Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) · Vol. ume No. 2 (2019) · pp. 1–10

DOI
10.70561/ica.v10i2.6650
ISSN
2655-6049, 2085-014X
Published
2019-05-30
Publisher
Hasanuddin University
Language
en

Abstract

A research on the characterization of the chloroform extract of leaves of M. umbellata (Houtt.) stapf var. degrabrata K. and activity test as antihyperglycemic has been done. This study aimed to isolate and characterize compounds from chloroform extract and determine the optimum concentration of chloroform extract in reducing blood glucose levels. Isolation compound from chloroform extract has been done by maceration, fractionation and purification. Based on the data of IR and NMR spectroscopic, compounds isolated from this research were β-sitosterol and fatty acid compound consisting of 25 carbon atoms. The glucose tolerance test, concentration of 6% showed a decrease in glucose levels almost equivalent with drug glibenclamide as comparator.

Keywords

Collaboration network of the authors

17 authors · 34 co-authorship links

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Ahyar AhmadAffiliation unknown2
Firdaus FirdausAffiliation unknown2
Hasnah NatsirAffiliation unknown2
Sulastrianah SulastrianahAffiliation unknown1
Eka Suci FitriaAffiliation unknown1
Seniwati DaliAffiliation unknown1
Eva JohannesAffiliation unknown1
ABDUL KARIMAffiliation unknown1
Rosmawaty RosmawatyAffiliation unknown1
Beddu JawahirAffiliation unknown1
Selfi WullurAffiliation unknown1
Muhammad ZakirAffiliation unknown1
Payapo Irfa ApriliyantiAffiliation unknown1
Musrifah TaharAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/ica/oai, first harvested 5 Nov 2026, last seen 5 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Characterization of Compounds From Extract of Leaf Cloroform Melochia umbellata (Houtt.) Stapf var. Degrabrata K.   and Test Antihiperglicemic Activities</dc:title>
	<dc:creator xml:lang="en">Imran, Imran</dc:creator>
	<dc:creator xml:lang="en">Hariani Soekamto, Nunuk</dc:creator>
	<dc:creator xml:lang="en">Usman, Hanapi</dc:creator>
	<dc:subject xml:lang="en">β-sitosterol</dc:subject>
	<dc:subject xml:lang="en">Glucose tolerance test</dc:subject>
	<dc:subject xml:lang="en">chloroform extract</dc:subject>
	<dc:subject xml:lang="en">and Melochia umbellate</dc:subject>
	<dc:description xml:lang="en">A research on the characterization of the chloroform extract of leaves of M. umbellata (Houtt.) stapf var. degrabrata K. and activity test as antihyperglycemic has been done. This study aimed to isolate and characterize compounds from chloroform extract and determine the optimum concentration of chloroform extract in  reducing blood glucose levels. Isolation compound from chloroform extract has been done by maceration, fractionation and purification. Based on the data of IR and NMR spectroscopic, compounds isolated from this research were β-sitosterol and fatty acid compound consisting of 25 carbon atoms. The glucose tolerance test, concentration of 6% showed a decrease in glucose levels almost equivalent with drug glibenclamide as comparator. </dc:description>
	<dc:publisher xml:lang="en">Hasanuddin University</dc:publisher>
	<dc:date>2019-05-30</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/ica/article/view/6650</dc:identifier>
	<dc:identifier>10.70561/ica.v10i2.6650</dc:identifier>
	<dc:source xml:lang="en">Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta); Volume 10, No.2: December 2017; 1-10</dc:source>
	<dc:source>2655-6049</dc:source>
	<dc:source>2085-014X</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/ica/article/view/6650/3620</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2017 Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta)</dc:rights>
</oai_dc:dc>