Melola Discovery

← Melola Discovery

Open access Jurnal

An Antioxidant and Toxicity Test as Anticancer of Jewawut Extract (Setaria italica L.) Local Varieties of West Sulawesi

Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) · Vol. ume No. 2 (2024) · pp. 85–90

DOI
10.70561/ica.v17i2.40506
ISSN
2655-6049, 2085-014X
Published
2024-12-30
Publisher
Hasanuddin University
Language
en
License
creativecommons.org/licenses/by-sa/4.0

Abstract

Jewawut (Setaria italica L.) is a local plant that is widely found and consumed by the people of West Sulawesi. This cereal plant has various benefits, one of which is as an anticancer. So this study aims to determine the antioxidant and anticancer potential of methanol extract of Jewawut (Setaria italica L.). This research includes phytochemical test of secondary metabolites, antioxidant activity test with 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and identification of anticancer potential based on toxicity test with Brine Shrimp Lethality Test (BSLT) method. The results showed that the methanol extract of Jewawut (Setaria italica L.) contained secondary metabolite compounds including alkaloids, flavonoids, tannins, saponins, steroids and terpenoids. The extract has very weak antioxidant activity with an IC50 value of 4104.63 ppm and has potential as an anticancer with a toxicity value (LC50) of 41.65 μg/mL which means the toxicity is very strong.

Collaboration network of the authors

7 authors · 11 co-authorship links

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Firdaus FirdausAffiliation unknown1
Nunuk Hariani SoekamtoAffiliation unknown1
Syadza FirdausiahAffiliation unknown1
Nunuk Hariani SoekamtoAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/ica/oai, first harvested 5 Nov 2026, last seen 5 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">An Antioxidant and Toxicity Test as Anticancer of Jewawut Extract (Setaria italica L.) Local Varieties of West Sulawesi</dc:title>
	<dc:creator xml:lang="en">Tahar, Musrifah</dc:creator>
	<dc:creator xml:lang="en">Wahid, Masyitha</dc:creator>
	<dc:creator xml:lang="en">Hakim, Sufyan </dc:creator>
	<dc:description xml:lang="en">Jewawut (Setaria italica L.) is a local plant that is widely found and consumed by the people of West Sulawesi. This cereal plant has various benefits, one of which is as an anticancer. So this study aims to determine the antioxidant and anticancer potential of methanol extract of Jewawut (Setaria italica L.). This research includes phytochemical test of secondary metabolites, antioxidant activity test with 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and identification of anticancer potential based on toxicity test with Brine Shrimp Lethality Test (BSLT) method. The results showed that the methanol extract of Jewawut (Setaria italica L.) contained secondary metabolite compounds including alkaloids, flavonoids, tannins, saponins, steroids and terpenoids. The extract has very weak antioxidant activity with an IC50 value of 4104.63 ppm and has potential as an anticancer with a toxicity value (LC50) of 41.65 μg/mL which means the toxicity is very strong.</dc:description>
	<dc:publisher xml:lang="en">Hasanuddin University</dc:publisher>
	<dc:date>2024-12-30</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/ica/article/view/40506</dc:identifier>
	<dc:identifier>10.70561/ica.v17i2.40506</dc:identifier>
	<dc:source xml:lang="en">Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta); Volume 17, No 2: December 2024; 85-90</dc:source>
	<dc:source>2655-6049</dc:source>
	<dc:source>2085-014X</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/ica/article/view/40506/12440</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2024 Musrifah Tahar</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by-sa/4.0</dc:rights>
</oai_dc:dc>