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Survivability Rates Based on Molecular Subtype, Stage and Metastasis of 36 months cohort in Breast Cancer Patients

Nusantara Medical Science Journal · Vol. ume (2022) · hlm. 29–38

DOI
10.20956/nmsj.v7i1.20092
ISSN
2597-7288, 2460-9757
Terbit
2022-04-16
Penerbit
Faculty of Medicine, Hasanuddin University.
Bahasa
en
Lisensi
creativecommons.org/licenses/by/4.0

Abstrak

Introduction: Breast cancer treatment is carried out at the early stage of the disease, and a comprehensive assessment of the subtype, stage, and incidence of metastases is required. This study aims to determine breast cancer patients' overall survival (OS) and disease-free survival (DFS) based on subtype, stage, and incidence of metastases. Methods: An observational analytic study with a retrospective cohort design was performed on eligible breast cancer patients at Wahidin Sudirohusodo Hospital from 2016 to 2019. Univariate analysis, and the Kaplan-Meier survival log-rank method (Mantel-Cox), were used to determine differences in survivability rates (OS and DFS) based on subtype, stage, and incidence of metastases. Results: A total of 172 breast cancer patients from 32 years to 84 years with a mean age of 53.5 years. The most subtypes were Luminal A (34.9%) patients, and the least was Luminal B (15.7%) patients. A total of 85 (49.4%) patients survived during these three years, while 87 (50.6%) died. Based on the results of statistical tests in this study, there were no significant differences between the subtypes with DFS and OS, but on the contrary, there was a significant difference between the stage and incidence of metastases with OS and DFS (p<0.05). Conclusions: There were no statistically significant differences between the subtypes with OS and DFS. This study showed a significant difference between the stage and incidence of metastases with OS and DFS

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  • Hasanuddin University
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Rekan penulisOrganisasiArtikel bersama
Haryasena HaryasenaHasanuddin University1
Daniel SampepajungAfiliasi tidak diketahui1
Akhtar Fajar MuzakkirHasanuddin University1
Aussie Fitriani GhaznawieHasanuddin University1
Fathlina FathlinaAfiliasi tidak diketahui1
Ali Aspar MappahyaAfiliasi tidak diketahui1
Abdul Hakim AlkatiriAfiliasi tidak diketahui1
Andi Alfian ZainuddinHasanuddin University1

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/jmednus/oai, pertama di-harvest 5 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">Survivability Rates Based on Molecular Subtype, Stage and Metastasis of 36 months cohort in Breast Cancer Patients</dc:title>
	<dc:creator xml:lang="en">Wijayanto, Adi</dc:creator>
	<dc:creator xml:lang="en">Pieter, John S. L. A.</dc:creator>
	<dc:creator xml:lang="en">Prihantono, P.</dc:creator>
	<dc:creator xml:lang="en">Syamsu, Salman Ardy</dc:creator>
	<dc:creator xml:lang="en">Thaufix, Nilam Smaradhania</dc:creator>
	<dc:creator xml:lang="en">Abdi, Amirullah</dc:creator>
	<dc:description xml:lang="en">Introduction:  Breast cancer treatment is carried out at the early stage of the disease, and a comprehensive assessment of the subtype, stage, and incidence of metastases is required. This study aims to determine breast cancer patients' overall survival (OS) and disease-free survival (DFS) based on subtype, stage, and incidence of metastases. Methods:  An observational analytic study with a retrospective cohort design was performed on eligible breast cancer patients at Wahidin Sudirohusodo Hospital from 2016 to 2019. Univariate analysis, and the Kaplan-Meier survival log-rank method (Mantel-Cox), were used to determine differences in survivability rates (OS and DFS) based on subtype, stage, and incidence of metastases. Results:   A total of 172 breast cancer patients from 32 years to 84 years with a mean age of 53.5 years. The most subtypes were Luminal A (34.9%) patients, and the least was Luminal B (15.7%) patients. A total of 85 (49.4%) patients survived during these three years, while 87 (50.6%) died. Based on the results of statistical tests in this study, there were no significant differences between the subtypes with DFS and OS, but on the contrary, there was a significant difference between the stage and incidence of metastases with OS and DFS (p&amp;lt;0.05). Conclusions:  There were no statistically significant differences between the subtypes with OS and DFS. This study showed a significant difference between the stage and incidence of metastases with OS and DFS</dc:description>
	<dc:publisher xml:lang="en">Faculty of Medicine, Hasanuddin University.</dc:publisher>
	<dc:date>2022-04-16</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/jmednus/article/view/20092</dc:identifier>
	<dc:identifier>10.20956/nmsj.v7i1.20092</dc:identifier>
	<dc:source xml:lang="en">Nusantara Medical Science Journal; Volume 7 Issue 1, January - June 2022; 29-38</dc:source>
	<dc:source>2597-7288</dc:source>
	<dc:source>2460-9757</dc:source>
	<dc:source>10.20956/nmsj.v7i1</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/jmednus/article/view/20092/8106</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2022 Nusantara Medical Science Journal</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by/4.0</dc:rights>
</oai_dc:dc>