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Right Ventricle Free Wall Longitudinal Strain in Cancer Patients Following Chemotherapy

Nusantara Medical Science Journal · Vol. ume (2023) · pp. 38–46

DOI
10.20956/nmsj.v8i1.26648
ISSN
2597-7288, 2460-9757
Published
2023-08-02
Publisher
Faculty of Medicine, Hasanuddin University.
Language
en
License
creativecommons.org/licenses/by/4.0

Abstract

Introduction: The survival rate of cancer patients was high due to chemotherapy, but it can cause cardiotoxicity and increase morbidity and mortality. Most studies on cancer therapy-related cardiac dysfunction (CTRCD) focus more on the left ventricle. This study assesses chemotherapy's effect on the right ventricle, namely the right ventricle free wall longitudinal strain (RVFWLS). Methods: This study is a prospective cohort conducted from January to December 2022 on thirty-four cancer patients undergoing chemotherapy at Dr Wahidin Sudirohusodo Hospital Makassar. The RVFWLS was assessed before and after chemotherapy using echocardiographic. Result: The RVFWLS value after one cycle chemotherapy decreased compared pre-chemotherapy (4.40±4.84; p=0.001). Conclusion: The effect of chemotherapy is a decrease the RVFWLS value after the first cycle of chemotherapy. It should be considered for echocardiographic evaluation, especially the RVFWLS value every cycle of chemotherapy.

Collaboration network of the authors

34 authors · 105 co-authorship links

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  • Hasanuddin University
  • Affiliation unknown
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Co-authorOrganisationJoint articles
Idar MappangaraHasanuddin University2
Muzakkir AmirAffiliation unknown2
Sumin SuminAffiliation unknown1
Khairawati KhairawatiAffiliation unknown1
Haryasena HaryasenaAffiliation unknown1
Daniel SampepajungAffiliation unknown1
Burhanuddin BaharAffiliation unknown1
Peter KaboAffiliation unknown1
Akhtar F. MuzakkirAffiliation unknown1
Khalid SalehAffiliation unknown1
Frizt A. TandeanAffiliation unknown1
Zainab AzisAffiliation unknown1
M. Husni CangaraAffiliation unknown1
Syarifuddin WahidAffiliation unknown1
Nita MarianaAffiliation unknown1
Upik A. MiskadAffiliation unknown1
Cahyono KaelanAffiliation unknown1
Rina MasadahAffiliation unknown1
Jane Magdalena KalatikuAffiliation unknown1
Berti J NelwanAffiliation unknown1
Djumadi AchmadAffiliation unknown1
Zaenab DjafarAffiliation unknown1
Andi Muhammad Akram KastiranAffiliation unknown1
Melda WarlianiAffiliation unknown1
Rini Rachmawarni BachtiarAffiliation unknown1
Rahmawati Minhajat1Affiliation unknown1
Sri JayantiAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/jmednus/oai, first harvested 5 Nov 2026, last seen 5 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Right Ventricle Free Wall Longitudinal Strain in Cancer Patients Following Chemotherapy</dc:title>
	<dc:creator xml:lang="en">Ghaznawie, Aussie Fitriani</dc:creator>
	<dc:creator xml:lang="en">Muzakkir, Akhtar Fajar</dc:creator>
	<dc:creator xml:lang="en">Fathlina, F.</dc:creator>
	<dc:creator xml:lang="en">Mappahya, Ali Aspar</dc:creator>
	<dc:creator xml:lang="en">Alkatiri, Abdul Hakim</dc:creator>
	<dc:creator xml:lang="en">Zainuddin, Andi Alfian</dc:creator>
	<dc:creator xml:lang="en">Prihantono, Prihantono</dc:creator>
	<dc:description xml:lang="en">Introduction: The survival rate of cancer patients was high due to chemotherapy, but it can cause cardiotoxicity and increase morbidity and mortality. Most studies on cancer therapy-related cardiac dysfunction (CTRCD) focus more on the left ventricle. This study assesses chemotherapy's effect on the right ventricle, namely the right ventricle free wall longitudinal strain (RVFWLS).
Methods: This study is a prospective cohort conducted from January to December 2022 on thirty-four cancer patients undergoing chemotherapy at Dr Wahidin Sudirohusodo Hospital Makassar. The RVFWLS was assessed before and after chemotherapy using 
echocardiographic. 
Result: The RVFWLS value after one cycle chemotherapy decreased compared pre-chemotherapy (4.40±4.84; p=0.001). Conclusion: The effect of chemotherapy is a decrease the RVFWLS value after the first cycle of chemotherapy. It should be considered for echocardiographic evaluation, especially the RVFWLS value every cycle of chemotherapy.</dc:description>
	<dc:publisher xml:lang="en">Faculty of Medicine, Hasanuddin University.</dc:publisher>
	<dc:date>2023-08-02</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/jmednus/article/view/26648</dc:identifier>
	<dc:identifier>10.20956/nmsj.v8i1.26648</dc:identifier>
	<dc:source xml:lang="en">Nusantara Medical Science Journal; Volume 8 Issue 1, January - June 2023; 38-46</dc:source>
	<dc:source>2597-7288</dc:source>
	<dc:source>2460-9757</dc:source>
	<dc:source>10.20956/nmsj.v8i1</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/jmednus/article/view/26648/10181</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2023 Nusantara Medical Science Journal</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by/4.0</dc:rights>
</oai_dc:dc>