Periode Waktu Inisiasi Anti-Retroviral Terapi (ART) Berhubungan dengan Perbedaan Outcome dan Tingkat Kadar CD4 pada Kasus HIV Positif

Putri, Wayan Citra Wulan Sucipta; Sawitri, Anak Agung Sagung; Sari, Komang Ayu Kartika

doi:10.30597/mkmi.v14i3.4123

Akses terbuka Jurnal

Periode Waktu Inisiasi Anti-Retroviral Terapi (ART) Berhubungan dengan Perbedaan Outcome dan Tingkat Kadar CD4 pada Kasus HIV Positif

Media Kesehatan Masyarakat Indonesia · Vol. 14 No. 3 (2018) · hlm. 217–224

DOI: 10.30597/mkmi.v14i3.4123
ISSN: 2356-4067, 0216-2482
Terbit: 2018-09-20
Penerbit: Faculty of Public Health, Hasanuddin University, Makassar
Bahasa: en
Lisensi: creativecommons.org/licenses/by-nc-sa/4.0

Abstrak

Early ART (Anti Retroviral Therapy) treatment at higher CD4 levels is believed to provide better outcomes.This study aims to determine the differences in outcomes and levels of CD4 levels based on the initiation periodof ART in HIV positive patients. This is a retrospective study, using secondary data to see differences in outcomes(CD4, morbidity, morbidity, lost to follow-up) of patients based on time-span status of ART initiation. The studypopulation was all HIV-positive patients who were or had undergone antiretroviral therapy in Denpasar City. Atotal of 312 patients were included in the study according to the criteria. The results showed that the proportionof subjects who had a CD4 cell rise of only 0-99sel/mm3 tended to be greater in the group who started ART morethan 12 weeks compared to those who started ART 12 weeks down (44.7% vs 36.7%). Vice versa, the proportionof subjects who had a CD4 increase ≥100 cells/mm3 was greater in the ART initiation group ≤12 weeks (73.3% vs55.3%) p=0.046. The proportion of subjects who died and lost to follow up was greater in the subjects who startedART over 12 weeks than the opposite (respectively 11% and 24.2% vs 5% and 12.7%, p=0.003). Significant differenceswere also seen, the proportion of subjects who were still on HAART was greater in the group of subjects whoinitiated HAART ≤12 weeks (64.8% vs 82.4%, p=0.003).

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Udayana University
Australian National University
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Rekan penulis	Organisasi	Artikel bersama
Putu Cintya Denny Yuliyatni	Udayana University	1
Ni Made Setiawati	Afiliasi tidak diketahui	1
Cokorda Bagus Jaya Lesmana	Udayana University	1
I Made Bakta	Udayana University	1
I Nyoman Sutarsa	Australian National University	1
Tuti Parwati Merati	Udayana University	1
Dewa Nyoman Wirawan	Udayana University	1
Pande Putu Januraga	Udayana University	1
I Made Ady Wirawan	Udayana University	1
Ni Wayan Tianing	Udayana University	1
Ni Made Utami Dwipayanti	Afiliasi tidak diketahui	1
Ni Made Swasti Wulanyani	Udayana University	1
Dyah Kanya Wati	Udayana University	1
Desak Putu Yuli Kurniati	Udayana University	1
Ni Luh Putu Rita Primayuni	Udayana University	1

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/mkmi/oai, pertama di-harvest 5 Nov 2026, terakhir terlihat 8 Nov 2026.

Metadata asli (oai_dc)

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	<dc:title xml:lang="en">Periode Waktu Inisiasi Anti-Retroviral Terapi (ART) Berhubungan dengan Perbedaan Outcome dan Tingkat Kadar CD4 pada Kasus HIV Positif</dc:title>
	<dc:creator xml:lang="en">Putri, Wayan Citra Wulan Sucipta</dc:creator>
	<dc:creator xml:lang="en">Sawitri, Anak Agung Sagung</dc:creator>
	<dc:creator xml:lang="en">Sari, Komang Ayu Kartika</dc:creator>
	<dc:subject xml:lang="en">HIV</dc:subject>
	<dc:subject xml:lang="en">CD4</dc:subject>
	<dc:subject xml:lang="en">ART</dc:subject>
	<dc:subject xml:lang="en">waktu inisiasi</dc:subject>
	<dc:description xml:lang="en">Early ART (Anti Retroviral Therapy) treatment at higher CD4 levels is believed to provide better outcomes.This study aims to determine the differences in outcomes and levels of CD4 levels based on the initiation periodof ART in HIV positive patients. This is a retrospective study, using secondary data to see differences in outcomes(CD4, morbidity, morbidity, lost to follow-up) of patients based on time-span status of ART initiation. The studypopulation was all HIV-positive patients who were or had undergone antiretroviral therapy in Denpasar City. Atotal of 312 patients were included in the study according to the criteria. The results showed that the proportionof subjects who had a CD4 cell rise of only 0-99sel/mm3 tended to be greater in the group who started ART morethan 12 weeks compared to those who started ART 12 weeks down (44.7% vs 36.7%). Vice versa, the proportionof subjects who had a CD4 increase ≥100 cells/mm3 was greater in the ART initiation group ≤12 weeks (73.3% vs55.3%) p=0.046. The proportion of subjects who died and lost to follow up was greater in the subjects who startedART over 12 weeks than the opposite (respectively 11% and 24.2% vs 5% and 12.7%, p=0.003). Significant differenceswere also seen, the proportion of subjects who were still on HAART was greater in the group of subjects whoinitiated HAART ≤12 weeks (64.8% vs 82.4%, p=0.003).</dc:description>
	<dc:publisher xml:lang="en">Faculty of Public Health, Hasanuddin University, Makassar</dc:publisher>
	<dc:date>2018-09-20</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/mkmi/article/view/4123</dc:identifier>
	<dc:identifier>10.30597/mkmi.v14i3.4123</dc:identifier>
	<dc:source xml:lang="en">Media Kesehatan Masyarakat Indonesia; Vol. 14 No. 3: SEPTEMBER 2018; 217-224</dc:source>
	<dc:source>2356-4067</dc:source>
	<dc:source>0216-2482</dc:source>
	<dc:source>10.30597/mkmi.v14i3</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/mkmi/article/view/4123/pdf</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2018 Wayan Citra Wulan Sucipta Putri, Anak Agung Sagung Sawitri, Komang Ayu Kartika Sari</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by-nc-sa/4.0</dc:rights>
</oai_dc:dc>