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Prevalence and Risk Factors and Efforts to Reduce Dengue Fever and Dengue Hemorrhagic Fever Infections at PKU Muhammadiyah Gamping Hospital, Yogyakarta

Media Kesehatan Masyarakat Indonesia · Vol. 21 No. 4 (2025) · hlm. 370–378

DOI
10.65844/mkmi.v21i4.47066
ISSN
2356-4067, 0216-2482
Terbit
2025-12-31
Penerbit
Faculty of Public Health, Hasanuddin University, Makassar
Bahasa
en
Lisensi
creativecommons.org/licenses/by-nc-sa/4.0/

Abstrak

The incidence of Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) has increased sharply in recent decades, making these infections endemic in several parts of the world. The purpose of this study was to analyze the prevalence, risk factors, and efforts to reduce DF and DHF infections at PKU Muhammadiyah Gamping Hospital, Yogyakarta. This study employed an observational cross-sectional design. The study sample consisted of patients diagnosed with DF or DHF at general hospitals in Yogyakarta between January 2019 and December 2023 who met the inclusion and exclusion criteria. Patients with a DF or DHF diagnosis but incomplete data were excluded. Sampling was conducted using a consecutive sampling method, retrieving information from patient data recorded in medical records. The research obtained ethical approval from the PKU Muhammadiyah Gamping Hospital Ethics Committee under permit number 054/KEP-PKU/II/2024. A p-value of 0.005 indicates a correlation between the incidence of DF DHF and liver illness. The value of OR is 4.660. A p-value of 0.006 indicates a correlation between the occurrence of DF DHF and corticosteroid therapy. This study found that the incidence of Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) was correlated with diabetes, hypertension, kidney disease, and asthma/chronic lung disease, which were protective factors. However, liver disease and a history of corticosteroid therapy were identified as significant risk factors. These findings suggest that impaired liver function and long-term corticosteroid use may impair the immune response, increasing susceptibility to dengue infection and its severe manifestations. Therefore, clinical management and prevention strategies should prioritize monitoring of patients with liver impairment or those undergoing corticosteroid therapy, especially in dengue-endemic areas.

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  • Muhammadiyah University of Yogyakarta
  • University of Cyberjaya
  • University of Indonesia
  • Afiliasi tidak diketahui
  • Organisasi berbeda
  • Organisasi sama
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Rekan penulisOrganisasiArtikel bersama
K. KuntamanAfiliasi tidak diketahui1
WJ. PudjirahardjoAfiliasi tidak diketahui1
Prima WidayaniAfiliasi tidak diketahui1
Tri Wulandari KesetyaningsihAfiliasi tidak diketahui1
Warih Andan PuspitosariAfiliasi tidak diketahui1
Kellyana KellyanaAfiliasi tidak diketahui1
Amal Chalik SjaafAfiliasi tidak diketahui1
Adang BachtiarAfiliasi tidak diketahui1
Merita AriniAfiliasi tidak diketahui1
Anhari AchadiUniversity of Indonesia1

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/mkmi/oai, pertama di-harvest 5 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">Prevalence and Risk Factors and Efforts to Reduce Dengue Fever and Dengue Hemorrhagic Fever Infections at PKU Muhammadiyah Gamping Hospital, Yogyakarta</dc:title>
	<dc:creator xml:lang="en">Kusbaryanto, Kusbaryanto</dc:creator>
	<dc:creator xml:lang="en">bin Abdurrahman , Abdurrasyid</dc:creator>
	<dc:creator xml:lang="en">Listiowati , Ekorini</dc:creator>
	<dc:creator xml:lang="en">Alam Romadhon , Yusuf</dc:creator>
	<dc:creator xml:lang="en">Rosyida , Aisyah</dc:creator>
	<dc:subject xml:lang="en">Prevalence</dc:subject>
	<dc:subject xml:lang="en">Risk Factors</dc:subject>
	<dc:subject xml:lang="en">Dengue Fever</dc:subject>
	<dc:subject xml:lang="en">Dengue Hemorrhagic Fever</dc:subject>
	<dc:subject xml:lang="en">Hospital</dc:subject>
	<dc:description xml:lang="en">The incidence of Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) has increased sharply in recent decades, making these infections endemic in several parts of the world. The purpose of this study was to analyze the prevalence, risk factors, and efforts to reduce DF and DHF infections at PKU Muhammadiyah Gamping Hospital, Yogyakarta. This study employed an observational cross-sectional design. The study sample consisted of patients diagnosed with DF or DHF at general hospitals in Yogyakarta between January 2019 and December 2023 who met the inclusion and exclusion criteria. Patients with a DF or DHF diagnosis but incomplete data were excluded. Sampling was conducted using a consecutive sampling method, retrieving information from patient data recorded in medical records. The research obtained ethical approval from the PKU Muhammadiyah Gamping Hospital Ethics Committee under permit number 054/KEP-PKU/II/2024. A p-value of 0.005 indicates a correlation between the incidence of DF DHF and liver illness. The value of OR is 4.660. A p-value of 0.006 indicates a correlation between the occurrence of DF DHF and corticosteroid therapy. This study found that the incidence of Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) was correlated with diabetes, hypertension, kidney disease, and asthma/chronic lung disease, which were protective factors. However, liver disease and a history of corticosteroid therapy were identified as significant risk factors. These findings suggest that impaired liver function and long-term corticosteroid use may impair the immune response, increasing susceptibility to dengue infection and its severe manifestations. Therefore, clinical management and prevention strategies should prioritize monitoring of patients with liver impairment or those undergoing corticosteroid therapy, especially in dengue-endemic areas.</dc:description>
	<dc:publisher xml:lang="en">Faculty of Public Health, Hasanuddin University, Makassar</dc:publisher>
	<dc:date>2025-12-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/mkmi/article/view/47066</dc:identifier>
	<dc:identifier>10.65844/mkmi.v21i4.47066</dc:identifier>
	<dc:source xml:lang="en">Media Kesehatan Masyarakat Indonesia; Vol. 21 No. 4: DECEMBER 2025; 370-378</dc:source>
	<dc:source>2356-4067</dc:source>
	<dc:source>0216-2482</dc:source>
	<dc:source>10.30597/mkmi.v21i4</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/mkmi/article/view/47066/14092</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2025 by author</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by-nc-sa/4.0/</dc:rights>
</oai_dc:dc>