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Efektivitas Ekstrak Daun Eceng Gondok Eichornia crassipes Sebagai Bahan Antikanker pada Sel Tumor MCF-7 dengan Metode In Vitro dan In Silico

Jurnal Ilmu Alam dan Lingkungan · Vol. 12 No. 1 (2021)

DOI
10.70561/jal.v12i1.13095
ISSN
2549-8819, 2086-4604
Published
2021-03-01
Publisher
Universitas Hasanuddin
Language
en

Abstract

The use of water hyacinth Eichhornia crassipes bioactive compounds has been developed, including as an anti-cancer base material. This study aims to examine the potential of water hyacinth leaf extract on MCF-7 tumor cells with the MTT method and the affinity of the water hyacinth leaf compound using molecular docking methods. The results showed the effect of water hyacinth leaf extract on MCF-7 cancer cell death due to the active compounds stigmasterol and phytol, while the docking results showed the best binding affinity value on stigmasterol and its receptor 1QR1 which was -9.4.

Collaboration network of the authors

40 authors · 124 co-authorship links · showing the 40 most connected

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  • Sunan Kalijaga State Islamic University Yogyakarta
  • Universitas Sulawesi Tenggara
  • Institut Agama Islam Negeri Kendari
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Sjafaraenan SjafaraenanAffiliation unknown9
Elis TambaruAffiliation unknown7
Magdalena LitaayAffiliation unknown3
Rosana AgusAffiliation unknown3
SjafaraenanAffiliation unknown2
Slamet SantosaAffiliation unknown2
Willem MokaAffiliation unknown2
Baharuddin PatandjengiAffiliation unknown2
Resti Ura’Affiliation unknown2
Fahruddin FahruddinSunan Kalijaga State Islamic University Yogyakarta2
Nur HaedarAffiliation unknown2
Ulfah Nur AmaliahAffiliation unknown1
Munif S HasanAffiliation unknown1
Syahribulan SyahribulanAffiliation unknown1
Nur Ramaliani SamsulAffiliation unknown1
Evy Noviana NovianaAffiliation unknown1
Herwin HerwinUniversitas Sulawesi Tenggara1
Jennyta Dhewi Darmansyah TanjungAffiliation unknown1
Jennyta Dhewi Darmansyah TanjungAffiliation unknown1
Handayani LolodatuAffiliation unknown1
Arfan SabranAffiliation unknown1
Siti Nadya WulandariAffiliation unknown1
Henra -Affiliation unknown1
Abdul SalamInstitut Agama Islam Negeri Kendari1
Fuad GaniAffiliation unknown1
Zaraswati DwyanaAffiliation unknown1
Muhammad Ruslan UmarAffiliation unknown1
Nur Umriani P UmarAffiliation unknown1
Nenis SardianiAffiliation unknown1
Mutia Putri JamaluddinAffiliation unknown1
M. Bayu MarioAffiliation unknown1
Tutik KuswinantiAffiliation unknown1
Ramdani RamdaniAffiliation unknown1
Afriyanda AfriyandaAffiliation unknown1
Olivia Datu ParungAffiliation unknown1
Hanapi UsmanAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/jai2/oai, first harvested 5 Nov 2026, last seen 5 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Efektivitas Ekstrak Daun Eceng Gondok Eichornia crassipes Sebagai Bahan Antikanker pada Sel Tumor MCF-7 dengan Metode In Vitro dan In Silico</dc:title>
	<dc:creator xml:lang="en">Eva Johannes</dc:creator>
	<dc:creator xml:lang="en">Andi Ilham Latunra</dc:creator>
	<dc:creator xml:lang="en">Tuwo, Mustika</dc:creator>
	<dc:creator xml:lang="en">Sry Sukmawaty</dc:creator>
	<dc:description xml:lang="en">The use of water hyacinth Eichhornia crassipes bioactive compounds has been developed, including as an anti-cancer base material. This study aims to examine the potential of water hyacinth leaf extract on MCF-7 tumor cells with the MTT method and the affinity of the water hyacinth leaf compound using molecular docking methods. The results showed the effect of water hyacinth leaf extract on MCF-7 cancer cell death due to the active compounds stigmasterol and phytol, while the docking results showed the best binding affinity value on stigmasterol and its receptor 1QR1 which was -9.4.</dc:description>
	<dc:publisher xml:lang="en">Universitas Hasanuddin</dc:publisher>
	<dc:date>2021-03-01</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/jai2/article/view/13095</dc:identifier>
	<dc:identifier>10.70561/jal.v12i1.13095</dc:identifier>
	<dc:source xml:lang="en">Jurnal Ilmu Alam dan Lingkungan; Vol. 12 No. 1 (2021): Jurnal Ilmu Alam dan Lingkungan</dc:source>
	<dc:source>2549-8819</dc:source>
	<dc:source>2086-4604</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/jai2/article/view/13095/6552</dc:relation>
</oai_dc:dc>