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KADAR ENZIM KOLINESTERASE TIKUS WISTAR (Rattus norvegicus) YANG TERPAPAR SIPERMETRIN

Jurnal IPTEKS Pemanfaatan Sumberdaya Perikanan · Vol. 3 No. 5 (2017)

DOI
10.20956/jipsp.v3i5.2081
ISSN
2614-5014, 2355-729X
Published
2017-07-16
Publisher
Hasanuddin University
Language
en

Abstract

Sipermetrin bersifat neurotoksin dan dapat mempengaruhi kadar enzim kolinesterase. Sipermetrin ditemukan terdapat pada produk Jambal Roti dengan kadar yang melebihi batas maksimum residu yang diperkenankan SNI dan CAC. Penelitian ini bertujuan untuk mengetahui pengaruh sipermetrin terhadap kadar enzim kolinesterase Tikus Wistar (Rattus norvegicus). Tikus diberi perlakuan paparan sipermetrin dengan dosis 0,00 mg/kg (K-), 0,05 mg/kg, 0,60 mg/kg, 1,10 mg/kg, 1,60 mg/kg, 2,15 mg/kg dan daging ikan yangmengandung sipermetrin 1,73 mg/kg (kontrol positif: K+). Kadar enzim kolinesterase darah tikus ditetapkan berdasarkan metode Enzymatic Photometric. Hasil menunjukkan bahwa sipermetrin berpengaruh terhadap penurunan kadar enzim kolinesterase Tikus Wistar. Kadar enzim kolinesterase terendah pada perlakuan paparan sipermetrin dosis 2,15 mg/kg yaitu 4059.9 U/L.

Collaboration network of the authors

40 authors · 141 co-authorship links · showing the 40 most connected

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Co-authorOrganisationJoint articles
Metusalach MetusalachAffiliation unknown9
. SyahrulAffiliation unknown3
Nur HafifahAffiliation unknown2
Elmi N. ZainuddinAffiliation unknown2
Syahrul SyahrulAffiliation unknown2
Kasmiati KasmiatiAffiliation unknown2
Ophirtus SumuleAffiliation unknown2
Mufti Hatur RahmiAffiliation unknown2
Yuniwaty HalimAffiliation unknown1
Ratna HandayaniAffiliation unknown1
Shella Trey LamtoroAffiliation unknown1
Asyhabul QaffiAffiliation unknown1
Wahdanial FitriAffiliation unknown1
Mufti Hatur Rahmi TahirAffiliation unknown1
Rara PasolangAffiliation unknown1
Nur Rezki FitrianiAffiliation unknown1
Ahmad DaniAffiliation unknown1
Gebi MassingAffiliation unknown1
Maria Cecelia PeniAffiliation unknown1
Yenni Cahya SikalaAffiliation unknown1
Sulfina AbriantiAffiliation unknown1
Syafiqah Mangkawani CanengAffiliation unknown1
Rendy Nugraha BidanganAffiliation unknown1
Marcellino Eliah MinangaAffiliation unknown1
Ilham JayaAffiliation unknown1
Muhammad Dalvi MustafaAffiliation unknown1
Marlina AhmadAffiliation unknown1
Ryan Ma’rup RamadhanAffiliation unknown1
Alisha Shafa AzzahraAffiliation unknown1
INA SUNDARIAffiliation unknown1
Jecly PaembonanAffiliation unknown1
Nur Fauzi ZaahirahAffiliation unknown1
Muh Naufal BissawabAffiliation unknown1
Kevin Putra SenawiAffiliation unknown1
Syeli Novita Putri EmbutatobaAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.unhas.ac.id/index.php/iptekspsp/oai, first harvested 5 Nov 2026, last seen 5 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en">KADAR ENZIM KOLINESTERASE TIKUS WISTAR (Rattus norvegicus) YANG TERPAPAR SIPERMETRIN</dc:title>
	<dc:creator xml:lang="en">Amir, Nursinah</dc:creator>
	<dc:creator xml:lang="en">Suprayitno, Eddy</dc:creator>
	<dc:creator xml:lang="en">Hardoko, Hardoko</dc:creator>
	<dc:creator xml:lang="en">Nursyam, Happy</dc:creator>
	<dc:creator xml:lang="en">Fahrul, Fahrul</dc:creator>
	<dc:description xml:lang="en">Sipermetrin  bersifat  neurotoksin  dan  dapat  mempengaruhi  kadar  enzim kolinesterase. Sipermetrin ditemukan terdapat pada produk Jambal Roti dengan kadar yang melebihi batas maksimum residu yang diperkenankan SNI dan CAC. Penelitian ini bertujuan untuk mengetahui pengaruh sipermetrin terhadap kadar enzim kolinesterase Tikus Wistar (Rattus norvegicus). Tikus diberi perlakuan paparan sipermetrin dengan dosis 0,00 mg/kg (K-), 0,05 mg/kg, 0,60 mg/kg, 1,10 mg/kg, 1,60 mg/kg, 2,15 mg/kg dan daging ikan yangmengandung sipermetrin 1,73 mg/kg (kontrol positif : K+). Kadar enzim kolinesterase darah tikus ditetapkan berdasarkan metode Enzymatic Photometric.  Hasil menunjukkan bahwa sipermetrin berpengaruh terhadap penurunan kadar enzim kolinesterase Tikus Wistar.  Kadar enzim kolinesterase terendah pada perlakuan paparan sipermetrin dosis 2,15 mg/kg yaitu 4059.9 U/L.</dc:description>
	<dc:publisher xml:lang="en">Hasanuddin University</dc:publisher>
	<dc:date>2017-07-16</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Research article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unhas.ac.id/index.php/iptekspsp/article/view/2081</dc:identifier>
	<dc:identifier>10.20956/jipsp.v3i5.2081</dc:identifier>
	<dc:source xml:lang="en">Jurnal IPTEKS Pemanfaatan Sumberdaya Perikanan; Vol. 3 No. 5 (2016)</dc:source>
	<dc:source>2614-5014</dc:source>
	<dc:source>2355-729X</dc:source>
	<dc:source>10.20956/jipsp.v3i5</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://journal.unhas.ac.id/index.php/iptekspsp/article/view/2081/1758</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2017 Jurnal IPTEKS Pemanfaatan Sumberdaya Perikanan</dc:rights>
</oai_dc:dc>