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UJI RESISTENSI Mycobacterium tuberculosis TERHADAP OBAT ANTI TUBERKULOSIS (OAT) DENGAN METODE PENIPISAN

Life Science · Vol. 2 No. 1 (2012)

ISSN
2528-5009, 2252-6277
Terbit
2012-12-28
Penerbit
Universitas Negeri Semarang
Bahasa
eng

Abstrak

The purpose of this research is to find out the reaction of M. tuberculosis resistance to OAT whit dilution method. This research is exploration research with post randomized controlled design. Each sample made as suspension with Mc Farland 1 turbidity then experimented with PNB to detect Mycobacterium Other Than Tuberculosis (MOTT). Negative result of PNB experiment then resistance experimented. Resistance experiment grown in Lowenstein-Jeensen (L-J) medium as control and were mixed is L-J medium which had been added with each OAT that is Isoniazid 0,2 mg/L, Rifampisin 40 mg/L, Streptomisin 4 mg/L dan Etambutanol 2 mg/L. Experiment result of PNB shows that there are five negative sample and one MOTT positive sample. Resistance experiment with dilution shows that there are 5 sensitive samples to OAT. From the research it can be concluded that by dilution method is not really influencing M. tuberculosis resistance experiment to OAT.

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Sumber metadata: OAI-PMH (metadata jurnal) https://journal.unnes.ac.id/sju/index.php/UnnesJLifeSci/oai, pertama di-harvest 5 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc)
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	<dc:title xml:lang="en-US">UJI RESISTENSI Mycobacterium tuberculosis TERHADAP OBAT ANTI TUBERKULOSIS (OAT) DENGAN METODE PENIPISAN</dc:title>
	<dc:creator>Widayanti, Erna</dc:creator>
	<dc:creator>Harnina Bintari, Siti</dc:creator>
	<dc:creator>-, Darwani</dc:creator>
	<dc:description xml:lang="en-US">The purpose of this research is to find out the reaction of M. tuberculosis resistance to OAT whit dilution method. This research is exploration research with post randomized controlled design. Each sample made as suspension with Mc Farland 1 turbidity then experimented with PNB to detect Mycobacterium Other Than Tuberculosis (MOTT). Negative result of PNB experiment then resistance experimented. Resistance experiment grown in Lowenstein-Jeensen (L-J) medium as control and were mixed is L-J medium which had been added with each OAT that is Isoniazid 0,2 mg/L, Rifampisin 40 mg/L, Streptomisin 4 mg/L dan Etambutanol 2 mg/L. Experiment result of PNB shows that there are five negative sample and one MOTT positive sample. Resistance experiment with dilution shows that there are 5 sensitive samples to OAT. From the research it can be concluded that by dilution method is not really influencing M. tuberculosis resistance experiment to OAT.</dc:description>
	<dc:publisher xml:lang="en-US">Universitas Negeri Semarang</dc:publisher>
	<dc:date>2012-12-28</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unnes.ac.id/sju/UnnesJLifeSci/article/view/1546</dc:identifier>
	<dc:source xml:lang="en-US">Life Science; Vol 2 No 1 (2013)</dc:source>
	<dc:source>2528-5009</dc:source>
	<dc:source>2252-6277</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journal.unnes.ac.id/sju/UnnesJLifeSci/article/view/1546/1495</dc:relation>
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