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Senyawa Bioaktif Trichoderma erinaceum dan Trichoderma koningiopsis Serta Potensinya Sebagai Antibakteri

Life Science · Vol. 11 No. 2 (2022) · pp. 120–131

ISSN
2528-5009, 2252-6277
Published
2022-11-30
Publisher
Universitas Negeri Semarang
Language
eng

Abstract

Trichoderma erinaceum and Trichoderma koningiopsis are lignocellulolytic mold isolated from the Universitas Negeri Semarang which are thought to produce bioactive compounds and have potential as antibacterials. The purpose of this study was to determine the types of bioactive compounds produced by T. erinaceum and T. koningiopsis and to test their antibacterial activity. The crude extracts of Trichoderma erinaceum (TE) and Trichoderma koningiopsis (TK) were tested for their bioactive compounds by chemical test tube including alkaloid, phenolic, flavonoid, steroid/terpenoid, tannin, and saponin tests. Furthermore, antibacterial tests were carried out on Escherichia coli and Bacillus subtilis using the paper disc diffusion method. Chemical tube test showed that TE and TK produced bioactive compounds in the form of flavonoids, phenolics, terpenoids, and tannins. The results of the antibacterial activity test showed that TE inhibited the growth of E. coli more strongly than B. subtilis with diameter inhibition zone 5.3 mm and 4.3 mm, respectively, while TK inhibited the growth of B. subtilis more strongly than E. coli with diameter inhibition zone 5.3 mm and 3.4 mm, respectively. This study shows that T. erinaceum and T. koningiopsis produce bioactive compounds that have potential as antibacterials with weak-moderate inhibitory responses. Trichoderma erinaceum dan Trichoderma koningiopsis merupakan isolat kapang lignoselulolitik yang diisolasi dari lingkungan Universitas Negeri Semarang yang diduga dapat menghasilkan senyawa bioaktif dan berpotensi sebagai antibakteri. Tujuan dari penelitian ini adalah untuk mengetahui jenis senyawa bioaktif yang dihasilkan oleh T. erinaceum dan T. koningiopsis serta uji aktivitas antibakterinya. Ekstrak kasar Trichoderma erinaceum (TE) dan Trichoderma koningiopsis (TK) diuji kandungan senyawa bioaktifnya dengan uji tabung kimiawi meliputi uji alkaloid, fenolik, flavonoid, steroid/terpenoid, tanin, dan saponin. Selanjutnya, uji antibakteri dilakukan terhadap Escherichia coli dan Bacillus subtilis dengan metode difusi kertas cakram. Uji tabung kimiawi menunjukkan bahwa TE dan TK menghasilkan senyawa bioaktif berupa flavonoid, fenolik, terpenoid, dan tanin. Hasil uji aktivitas antibakteri menunjukkan TE lebih kuat menghambat pertumbuhan bakteri E.coli dibandingkan B. subtilis dengan diameter zona hambat 5,3 mm dan 4,3 mm secara berturut-turut, sedangkan TK lebih kuat menghambat pertumbuhan bakteri B. subtilis dibandingkan E. coli dengan diameter zona hambat 5,3 mm dan 3,4 mm secara berturut-turut. Penelitian ini menunjukkan bahwa T. erinaceum dan T. koningiopsis menghasilkan senyawa bioaktif yang berpotensi sebagai antibakteri dengan respon hambatan lemah-sedang. Keywords: Antibacterial; Bioactive compounds; Trichoderma Antibakteri; Senyawa bioaktif;; Trichoderma

Collaboration network of the authors

40 authors · 137 co-authorship links · 1 across different organisations · showing the 40 most connected

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

  • State University of Semarang
  • Diponegoro University
  • Universitas Sumatera Utara
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Siti Harnina BintariAffiliation unknown20
Ibnul MubarokAffiliation unknown4
Dyah Rini IndriyantiState University of Semarang3
Ghani WalandipaAffiliation unknown3
Priyantini WidiyaningrumAffiliation unknown2
Maria Ayu PuspitaAffiliation unknown2
Nunung Eni ElawatiAffiliation unknown2
Andhina Putri HeriyantiDiponegoro University2
Edi KurniawanUniversitas Sumatera Utara2
Sucihatiningsih Dian Wisika PrajantiState University of Semarang2
Niken SubektiState University of Semarang2
Ning SetiatiAffiliation unknown2
Ely RudyatmiAffiliation unknown2
Hasyim AbdurrasyidAffiliation unknown2
Mutiara Bintang RamadaniAffiliation unknown2
Astrid FarmayatiAffiliation unknown2
Lusi Maswahyu AndriyaniAffiliation unknown2
SunyotoAffiliation unknown2
Ernallah YatiAffiliation unknown1
Aura Tirsa MelindaAffiliation unknown1
Rahimma Artantia AnandaAffiliation unknown1
Orchida Puspa JelitaAffiliation unknown1
Delia Alifia FarrezaAffiliation unknown1
Supriyadi SupriyadiAffiliation unknown1
Kusmuriyanto KusmuriyantoAffiliation unknown1
Mochamad Nur SholikhinAffiliation unknown1
Nishfa MufatihahAffiliation unknown1
Sriyadi SriyadiAffiliation unknown1
Rusyida AuliyaAffiliation unknown1
Naeli Tamin QonitaAffiliation unknown1
Previanda ArditamaAffiliation unknown1
Fira Putri Nur AwwaliaAffiliation unknown1
Nana Kariada Tri MartutiAffiliation unknown1
Elfrida Theresia SiburianAffiliation unknown1
Nur Rahayu UtamiAffiliation unknown1
Stella FlorensiaAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.unnes.ac.id/sju/index.php/UnnesJLifeSci/oai, first harvested 5 Nov 2026, last seen 5 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">Senyawa Bioaktif Trichoderma erinaceum dan Trichoderma koningiopsis	Serta Potensinya Sebagai Antibakteri</dc:title>
	<dc:creator>Sulaiha, Siti</dc:creator>
	<dc:creator>Mustikaningtyas, Dewi</dc:creator>
	<dc:creator>Widiatningrum, Talitha</dc:creator>
	<dc:creator>Dewi, Pramesti</dc:creator>
	<dc:description xml:lang="en-US">Trichoderma erinaceum and Trichoderma koningiopsis are lignocellulolytic mold isolated from the Universitas Negeri Semarang which are thought to produce bioactive compounds and have potential as antibacterials. The purpose of this study was to determine the types of bioactive compounds produced by T. erinaceum and T. koningiopsis and to test their antibacterial activity. The crude extracts of Trichoderma erinaceum (TE) and Trichoderma koningiopsis (TK) were tested for their bioactive compounds by chemical test tube including alkaloid, phenolic, flavonoid, steroid/terpenoid, tannin, and saponin tests. Furthermore, antibacterial tests were carried out on Escherichia coli and Bacillus subtilis using the paper disc diffusion method. Chemical tube test showed that TE and TK produced bioactive compounds in the form of flavonoids, phenolics, terpenoids, and tannins. The results of the antibacterial activity test showed that TE inhibited the growth of E. coli more strongly than B. subtilis with diameter inhibition zone 5.3 mm and 4.3 mm, respectively, while TK inhibited the growth of B. subtilis more strongly than E. coli with diameter inhibition zone 5.3 mm and 3.4 mm, respectively. This study shows that T. erinaceum and T. koningiopsis produce bioactive compounds that have potential as antibacterials with weak-moderate inhibitory responses.
&amp;nbsp;
Trichoderma erinaceum dan Trichoderma koningiopsis merupakan isolat kapang lignoselulolitik yang diisolasi dari lingkungan Universitas Negeri Semarang yang diduga dapat menghasilkan senyawa bioaktif dan berpotensi sebagai antibakteri. Tujuan dari penelitian ini adalah untuk mengetahui jenis senyawa bioaktif yang dihasilkan oleh T. erinaceum dan T. koningiopsis serta uji aktivitas antibakterinya. Ekstrak kasar Trichoderma erinaceum (TE) dan Trichoderma koningiopsis (TK) diuji kandungan senyawa bioaktifnya dengan uji tabung kimiawi meliputi uji alkaloid, fenolik, flavonoid, steroid/terpenoid, tanin, dan saponin. Selanjutnya, uji antibakteri dilakukan terhadap Escherichia coli dan Bacillus subtilis dengan metode difusi kertas cakram. Uji tabung kimiawi menunjukkan bahwa TE dan TK menghasilkan senyawa bioaktif berupa flavonoid, fenolik, terpenoid, dan tanin. Hasil uji aktivitas antibakteri menunjukkan TE lebih kuat menghambat pertumbuhan bakteri E.coli dibandingkan B. subtilis dengan diameter zona hambat 5,3 mm dan 4,3 mm secara berturut-turut, sedangkan TK lebih kuat menghambat pertumbuhan bakteri B. subtilis dibandingkan E. coli dengan diameter zona hambat 5,3 mm dan 3,4 mm secara berturut-turut. Penelitian ini menunjukkan bahwa T. erinaceum dan T. koningiopsis menghasilkan senyawa bioaktif yang berpotensi sebagai antibakteri dengan respon hambatan lemah-sedang.
Keywords: Antibacterial; Bioactive compounds; Trichoderma Antibakteri; Senyawa bioaktif;; Trichoderma</dc:description>
	<dc:publisher xml:lang="en-US">Universitas Negeri Semarang</dc:publisher>
	<dc:date>2022-11-30</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
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	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unnes.ac.id/sju/UnnesJLifeSci/article/view/64380</dc:identifier>
	<dc:source xml:lang="en-US">Life Science; Vol 11 No 2 (2022): November 2022; 120-131</dc:source>
	<dc:source>2528-5009</dc:source>
	<dc:source>2252-6277</dc:source>
	<dc:source>10.15294/lifesci.v11i2</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journal.unnes.ac.id/sju/UnnesJLifeSci/article/view/64380/23345</dc:relation>
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