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Determinants of Dengue Hemorrhagic Fever Deaths: A Hospital-Based Cross-Sectional Study

Journal of Health Education · Vol. 9 No. 1 (2024) · hlm. 62–71

ISSN
2528-2905, 2527-4252
Terbit
2024-07-26
Penerbit
Universitas Negeri Semarang
Bahasa
eng

Abstrak

Background: The increase in the dengue mortality rate in Indonesia and its risk factors which must be addressed immediately. Brebes Hospital, a hospital that is the primary referral for health centers and clinics in Brebes Regency, has a dengue mortality rate (Case Fatality Rate) of 7.88%, contributing to the first death rate in Brebes Regency. Data related to dengue deaths, such as comorbidities and hematocrit levels in dengue patients, were unavailable at the provincial and Brebes district levels, especially at Brebes Hospital. This study aims to determine the determinants of dengue death in inpatients at Brebes Hospital. Methods: This cross-sectional study used medical record data of dengue inpatients from September 2021 to August 2022, with as many as 138 respondents using a simple random sampling technique. The research instrument is an observation sheet, including age, gender, incidence of thrombocytopenia, hypotension, hematocrit levels, hemoglobin levels, diabetes mellitus status, hypertension status, comorbidities, and LOS. The data were analyzed in univariate, bivariate with the chi-square test, and multivariate with a logistic regression test. Results: The bivariate analysis results showed that the variables of hypertension status, DM status, thrombocytopenia, hematocrit levels, and the presence of comorbid diseases were associated with dengue mortality (p<0.01). Multivariate analysis showed that after controlling for other variables, the risk of comorbid diseases was significant 27.54 times (p-value <0.001; AOR= 27.54; 95% CI= 7.21-105.07), and hematocrit levels were at risk of 4.96 times increasing dengue mortality (p-value = 0.005; AOR= 4.69; 95% CI= 1.59-13.83). Conclusion: Hematocrit levels and the presence of comorbid diseases are critical determinants of dengue case mortality. The central comorbid diseases are hypertension, diabetes, and stroke. These two factors must be the primary concern of the clinicians in charge of patients in anticipation of an emergency.

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Maulina IstighfarohAfiliasi tidak diketahui3
Sri Ratna RahayuAfiliasi tidak diketahui3
Irwan BudionoAfiliasi tidak diketahui2
Tandiyo RahayuAfiliasi tidak diketahui2
Nur SiyamAfiliasi tidak diketahui2
Mahalul AzamAfiliasi tidak diketahui1
Yuni WijayantiAfiliasi tidak diketahui1
Alfiana Ainun NisaAfiliasi tidak diketahui1
Seti Tyas KusumawardaniAfiliasi tidak diketahui1
Andry AkhiruyantoAfiliasi tidak diketahui1
Taufiq HidayahAfiliasi tidak diketahui1
Faiqotunnuriyah FaiqotunnuriyahAfiliasi tidak diketahui1
Adinda Yustika SeftianiAfiliasi tidak diketahui1
Avida FebianiAfiliasi tidak diketahui1
Afrilia Khusnul FitrianiAfiliasi tidak diketahui1
Lidya AngelinaAfiliasi tidak diketahui1
Retno WulandariAfiliasi tidak diketahui1
Eky Fadhildansyah AzharAfiliasi tidak diketahui1
Sofwan IndarjoState University of Semarang1
Muhammad AzinarAfiliasi tidak diketahui1
Zahra Amalia GardynaAfiliasi tidak diketahui1
Anna NugrahaniAfiliasi tidak diketahui1
Yemima Eka Sabat ThaniaAfiliasi tidak diketahui1
Alviar WahdaniahAfiliasi tidak diketahui1
Selva Dwi PrahastiAfiliasi tidak diketahui1
Rhanindra Aviana Yumna ShafiraAfiliasi tidak diketahui1
Silvi YantiAfiliasi tidak diketahui1
Diah HasanahAfiliasi tidak diketahui1
Wita Istiqomah TristantiAfiliasi tidak diketahui1
Widya Hary CahyatiAfiliasi tidak diketahui1
Michael Yong Hwa ChiaAfiliasi tidak diketahui1
Sukma AnandyagunaAfiliasi tidak diketahui1
Putri Royan DivaAfiliasi tidak diketahui1
Anggit Aprindrian PrehamuktiAfiliasi tidak diketahui1
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Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://journal.unnes.ac.id/journals/jhealthedu/oai, pertama di-harvest 6 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Determinants of Dengue Hemorrhagic Fever Deaths: A Hospital-Based Cross-Sectional Study</dc:title>
	<dc:creator xml:lang="en">Mailiana, Rizki</dc:creator>
	<dc:creator xml:lang="en">Fauzi, Lukman</dc:creator>
	<dc:subject xml:lang="en">Dengue Hemorrhagic Fever</dc:subject>
	<dc:subject xml:lang="en">Mortality</dc:subject>
	<dc:subject xml:lang="en">Risk Factors</dc:subject>
	<dc:subject xml:lang="en">Medical Records</dc:subject>
	<dc:description xml:lang="en">Background: The increase in the dengue mortality rate in Indonesia and its risk factors which must be addressed immediately. Brebes Hospital, a hospital that is the primary referral for health centers and clinics in Brebes Regency, has a dengue mortality rate (Case Fatality Rate) of 7.88%, contributing to the first death rate in Brebes Regency. Data related to dengue deaths, such as comorbidities and hematocrit levels in dengue patients, were unavailable at the provincial and Brebes district levels, especially at Brebes Hospital. This study aims to determine the determinants of dengue death in inpatients at Brebes Hospital. Methods: &amp;nbsp;This cross-sectional study used medical record data of dengue inpatients from September 2021 to August 2022, with as many as 138 respondents using a simple random sampling technique. The research instrument is an observation sheet, including age, gender, incidence of thrombocytopenia, hypotension, hematocrit levels, hemoglobin levels, diabetes mellitus status, hypertension status, comorbidities, and LOS. The data were analyzed in univariate, bivariate with the chi-square test, and multivariate with a logistic regression test. Results: The bivariate analysis results showed that the variables of hypertension status, DM status, thrombocytopenia, hematocrit levels, and the presence of comorbid diseases were associated with dengue mortality (p&amp;lt;0.01). Multivariate analysis showed that after controlling for other variables, the risk of comorbid diseases was significant 27.54 times (p-value &amp;lt;0.001; AOR= 27.54; 95% CI= 7.21-105.07), and hematocrit levels were at risk of 4.96 times increasing dengue mortality (p-value = 0.005; AOR= 4.69; 95% CI= 1.59-13.83). Conclusion: Hematocrit levels and the presence of comorbid diseases are critical determinants of dengue case mortality. The central comorbid diseases are hypertension, diabetes, and stroke. These two factors must be the primary concern of the clinicians in charge of patients in anticipation of an emergency.
&amp;nbsp;</dc:description>
	<dc:publisher xml:lang="en">Universitas Negeri Semarang</dc:publisher>
	<dc:date>2024-07-26</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unnes.ac.id/journals/jhealthedu/article/view/10056</dc:identifier>
	<dc:source xml:lang="en">Journal of Health Education; Vol. 9 No. 1 (2024); 62-71</dc:source>
	<dc:source>2528-2905</dc:source>
	<dc:source>2527-4252</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journal.unnes.ac.id/journals/jhealthedu/article/view/10056/1042</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2024 Journal of Health Education</dc:rights>
</oai_dc:dc>