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Optimizing Deep Learning Models with Custom ReLU for Breast Cancer Histopathology Image Classification

Scientific Journal of Informatics · Vol. 11 No. 3 (2024) · hlm. 849–862

DOI
10.15294/sji.v11i3.12722
ISSN
2407-7658, 2460-0040
Terbit
2024-11-06
Penerbit
Universitas Negeri Semarang
Bahasa
eng

Abstrak

Purpose: The prompt identification of breast cancer is crucial in preventing the considerable damage inflicted by this dangerous form of cancer, which is widely happened across the globe. This study seeks to refine the efficacy of a deep learning-driven approach for the precise diagnosis of breast cancer by employing diverse bespoke Rectified Linear Units (ReLU) to improve the model's performance and reduce inaccuracies within the system. Method: This study focuses on analyzing a deep learning approach utilizing the BreakHis dataset with 7,909 images, incorporating changes to the ReLU activation function across different pre-trained CNN models. It then evaluates performance through measurement such as accuracy, precision, recall, and F1-Score. Result: Based on our experiment results, it can be shown that the DenseNet201 models with a custom LeakyReLU excel beyond the typical ReLU, achieving the highest accuracy, recall, and F1-Score at 99.21%, 99.21%, and 99.11%, respectively. Simultaneously, ResNet152, utilizing LessNegativeReLU (α=0.05), achieved the highest precision at 99.11%. The VGG11 model exhibited the most notable performance enhancement, with improvements ranging from 1.39% to 1.59%. Novelty: The research is original in optimizing a model for accurate breast cancer diagnosis. The proposed model is superior to the model utilizing the default activation function. This finding indicates that the study significantly enhances performance while effectively minimizing errors, thereby necessitating further exploration into the effectiveness of the customized activation function when applied to other medical imaging modalities.

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26 penulis · 73 tautan kepenulisan bersama · 14 lintas organisasi

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  • Universitas Dian Nuswantoro
  • Institut Teknologi Sepuluh Nopember
  • State University of Semarang
  • Universitas Sains dan Teknologi Komputer
  • University of Malaya
  • Afiliasi tidak diketahui
  • Organisasi berbeda
  • Organisasi sama
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Tampilkan sebagai tabel
Rekan penulisOrganisasiArtikel bersama
Cinantya ParamitaUniversitas Dian Nuswantoro2
Waskitho WibisonoInstitut Teknologi Sepuluh Nopember1
Muchammad HusniInstitut Teknologi Sepuluh Nopember1
Edi Jaya KusumaUniversitas Dian Nuswantoro1
Ririn NurmandhaniAfiliasi tidak diketahui1
Lenci AryaniAfiliasi tidak diketahui1
Ika PantiawatiAfiliasi tidak diketahui1
Guruh Fajar ShidikAfiliasi tidak diketahui1
Ririn NurmandhaniUniversitas Dian Nuswantoro1
Lenci AryaniUniversitas Dian Nuswantoro1
Ika PantiawatiUniversitas Dian Nuswantoro1
Suprapto .Afiliasi tidak diketahui1
AmaliaAfiliasi tidak diketahui1
Khalivio Rahmyanto PutraUniversitas Dian Nuswantoro1
Aries Gilang SaputraUniversitas Dian Nuswantoro1
Purwanto PurwantoUniversitas Dian Nuswantoro1
Pulung Nurtantio AndonoUniversitas Dian Nuswantoro1
Sindhu RakasiwiUniversitas Sains dan Teknologi Komputer1
Shier Nee SawUniversity of Malaya1
Muhammad Ivan RafsanjaniUniversitas Dian Nuswantoro1
Oktavian Andi Cahya NugrahaUniversitas Dian Nuswantoro1
Catur SupriyantoUniversitas Dian Nuswantoro1

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Sumber metadata: OAI-PMH (metadata jurnal) https://journal.unnes.ac.id/journals/sji/oai, pertama di-harvest 6 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc)
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Optimizing Deep Learning Models with Custom ReLU for Breast Cancer Histopathology Image Classification</dc:title>
	<dc:creator xml:lang="en">Nugroho, Wahyu Adi</dc:creator>
	<dc:creator xml:lang="en">Supriyanto, Catur</dc:creator>
	<dc:creator xml:lang="en">Pujiono, Pujiono</dc:creator>
	<dc:creator xml:lang="en">Shidik, Guruh Fajar</dc:creator>
	<dc:subject xml:lang="en">Activation function</dc:subject>
	<dc:subject xml:lang="en">Breast cancer</dc:subject>
	<dc:subject xml:lang="en">Convolutional neural network</dc:subject>
	<dc:subject xml:lang="en">Custom ReLU</dc:subject>
	<dc:subject xml:lang="en">Deep learning</dc:subject>
	<dc:description xml:lang="en">Purpose: The prompt identification of breast cancer is crucial in preventing the considerable damage inflicted by this dangerous form of cancer, which is widely happened across the globe. This study seeks to refine the efficacy of a deep learning-driven approach for the precise diagnosis of breast cancer by employing diverse bespoke Rectified Linear Units (ReLU) to improve the model's performance and reduce inaccuracies within the system.
Method: This study focuses on analyzing a deep learning approach utilizing the BreakHis dataset with 7,909 images, incorporating changes to the ReLU activation function across different pre-trained CNN models. It then evaluates performance through measurement such as accuracy, precision, recall, and F1-Score.
Result: Based on our experiment results, it can be shown that the DenseNet201 models with a custom LeakyReLU excel beyond the typical ReLU, achieving the highest accuracy, recall, and F1-Score at 99.21%, 99.21%, and 99.11%, respectively. Simultaneously, ResNet152, utilizing LessNegativeReLU (α=0.05), achieved the highest precision at 99.11%. The VGG11 model exhibited the most notable performance enhancement, with improvements ranging from 1.39% to 1.59%.
Novelty: The research is original in optimizing a model for accurate breast cancer diagnosis. The proposed model is superior to the model utilizing the default activation function. This finding indicates that the study significantly enhances performance while effectively minimizing errors, thereby necessitating further exploration into the effectiveness of the customized activation function when applied to other medical imaging modalities.</dc:description>
	<dc:publisher xml:lang="en">Universitas Negeri Semarang</dc:publisher>
	<dc:date>2024-11-06</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unnes.ac.id/journals/sji/article/view/12722</dc:identifier>
	<dc:identifier>10.15294/sji.v11i3.12722</dc:identifier>
	<dc:source xml:lang="en">Scientific Journal of Informatics; Vol. 11 No. 3: Special Issue; 849-862</dc:source>
	<dc:source>2407-7658</dc:source>
	<dc:source>2460-0040</dc:source>
	<dc:source>10.15294/sji.v11i3</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journal.unnes.ac.id/journals/sji/article/view/12722/1976</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2024 Scientific Journal of Informatics</dc:rights>
</oai_dc:dc>