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The Effect of Edamame milk on Triglyceride Levels in Diabetes Wistar Rats

Sports Medicine Curiosity Journal · Vol. 1 No. 2 (2022) · hlm. 59–64

DOI
10.15294/smcj.v1i2.61645
ISSN
2962-6382, 2962-6374
Terbit
2022-11-30
Penerbit
Universitas Negeri Semarang
Bahasa
eng

Abstrak

Type 2 diabetes is a hyperglycemic disease caused by cell insensitivity due to increasing blood glucose levels due to reduced insulin secretion. Hyperglycemia conditions have the risk to increase triglyceride levels in type 2 diabetes. Edamame milk contained isoflavones that had potential to reduce triglyceride level. To find out the effect of given edamame milk on triglyceride levels in type 2 diabetes wistar rats. A true experimental with pre-post randomized control group design towards 24 type 2 diabetes wistar rats in 4 groups. Groups K(+), P1 and P2 were induced Streptozotocin 45 mg/kgBW and Nicotinamide 110 mg/kgBW. P1 and P2 groups were given edamame milk at a dose of 1,8 ml/200grBW and 3,6 ml/200grBW for 28 days. Blood samples were taken through a retro-orbitalis plexus. Triglyceride levels were tested pre and post intervention using the GPO-PAP method. Data analysis had used Paired T test and One Way ANOVA test with Post hoc follow-up test. Triglyceride levels in P1 and P2 groups had significant differences (p<0,05) against the control groups. Edamame milk could reduce triglyceride levels of groups P1 and P2 at dose 1,8 ml/200grBW and 3,6 ml/200grBW. P2 was the highest group reduced in triglyceride levels up to 29,41±3,55 mg/dL. Edamame milk could reduced triglycerides levels in 28 days. Given an edamame milk at a dose 3,6 ml/200grBW more efficient to reduce triglyceride levels in type 2 diabestes rats significantly

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Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">The Effect of Edamame milk on Triglyceride Levels in Diabetes Wistar Rats</dc:title>
	<dc:creator>Ajeng, Dhea</dc:creator>
	<dc:creator>Ardiaria, Martha</dc:creator>
	<dc:creator>Kurniawati, Dewi Marfu’ah</dc:creator>
	<dc:creator>Ayustaningwarno, Fitriyono</dc:creator>
	<dc:description xml:lang="en-US">Type 2 diabetes is a hyperglycemic disease caused by cell insensitivity due to increasing blood glucose levels due to reduced insulin secretion. Hyperglycemia conditions have the risk to increase triglyceride levels in type 2 diabetes. Edamame milk contained isoflavones that had potential to reduce triglyceride level. To find out the effect of given edamame milk on triglyceride levels in type 2 diabetes wistar rats. A true experimental with pre-post randomized control group design towards 24 type 2 diabetes wistar rats in 4 groups. Groups K(+), P1 and P2 were induced Streptozotocin 45 mg/kgBW and Nicotinamide 110 mg/kgBW. P1 and P2 groups were given edamame milk at a dose of 1,8 ml/200grBW and 3,6 ml/200grBW for 28 days. Blood samples were taken through a retro-orbitalis plexus. Triglyceride levels were tested pre and post intervention using the GPO-PAP method. Data analysis had used Paired T test and One Way ANOVA test with Post hoc follow-up test. Triglyceride levels in P1 and P2 groups had significant differences (p&amp;lt;0,05) against the control groups. Edamame milk could reduce triglyceride levels of groups P1 and P2 at dose 1,8 ml/200grBW and 3,6 ml/200grBW. P2 was the highest group reduced in triglyceride levels up to 29,41±3,55 mg/dL. Edamame milk could reduced triglycerides levels in 28 days. Given an edamame milk at a dose 3,6 ml/200grBW more efficient to reduce triglyceride levels in type 2 diabestes rats significantly</dc:description>
	<dc:publisher xml:lang="en-US">Universitas Negeri Semarang</dc:publisher>
	<dc:date>2022-11-30</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unnes.ac.id/sju/smcj/article/view/61645</dc:identifier>
	<dc:identifier>10.15294/smcj.v1i2.61645</dc:identifier>
	<dc:source xml:lang="en-US">Sports Medicine Curiosity Journal; Vol 1 No 2 (2022): October 2022; 59-64</dc:source>
	<dc:source>2962-6382</dc:source>
	<dc:source>2962-6374</dc:source>
	<dc:source>10.15294/smcj.v1i2</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journal.unnes.ac.id/sju/smcj/article/view/61645/23032</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2022 Sports Medicine Curiosity Journal</dc:rights>
</oai_dc:dc>