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Metabolite profile of 25% ethanol extract of Areca nut (Areca catechu) which has potential as an anti-inflammatory

Proceedings Academic Universitas Jambi · Vol. 1 No. 2 (2025) · hlm. 443–451

DOI
10.22437/proca.v1i2.50267
Terbit
2025-11-26
Penerbit
LPPM Universitas Jambi
Bahasa
en
Lisensi
creativecommons.org/licenses/by/4.0

Abstrak

Background: The areca nut plant has been preclinically tested for its pharmacological effects. A 25% ethanol extract is one type of extract suspected to have pharmacological potential. Objective: The purpose of this research is to describe the results of secondary metabolite profiles using LC-MS, which hopefully can provide an overview for further development. Methods: Extraction using the maceration method, then phytochemical screening, and preparation with methanol and DCM, then injected as much as 5 µl into UPLC-QToF-MS/MS, then analyzed with Masslynx 4.1 and Chemspider software. Results: The results have shown that the extract contained 12 compounds, several of which have the potential to be anti-inflammatory. Conclusion: Literature studies have several compounds that have the potential to be anti-inflammatory.

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Sumber metadata: OAI-PMH (metadata jurnal) https://online-journal.unja.ac.id/index.php/PROCA/oai, pertama di-harvest 6 Nov 2026, terakhir terlihat 6 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">Metabolite profile of 25% ethanol extract of Areca nut (Areca catechu) which has potential as an anti-inflammatory</dc:title>
	<dc:creator xml:lang="en">Humaryanto</dc:creator>
	<dc:creator xml:lang="en">Fairuz</dc:creator>
	<dc:creator xml:lang="en">Kasmadi, Fathnur Sani</dc:creator>
	<dc:creator xml:lang="en">Hanina</dc:creator>
	<dc:creator xml:lang="en">Perkasa, Tengku Arief Buana</dc:creator>
	<dc:subject xml:lang="en">Metabolites</dc:subject>
	<dc:subject xml:lang="en">Extract</dc:subject>
	<dc:subject xml:lang="en">Ethanol 25%</dc:subject>
	<dc:subject xml:lang="en">Areca catechu</dc:subject>
	<dc:description xml:lang="en">Background: The areca nut plant has been preclinically tested for its pharmacological effects. A 25% ethanol extract is one type of extract suspected to have pharmacological potential. Objective: The purpose of this research is to describe the results of secondary metabolite profiles using LC-MS, which hopefully can provide an overview for further development. Methods: Extraction using the maceration method, then phytochemical screening, and preparation with methanol and DCM, then injected as much as 5 µl into UPLC-QToF-MS/MS, then analyzed with Masslynx 4.1 and Chemspider software. Results: The results have shown that the extract contained 12 compounds, several of which have the potential to be anti-inflammatory. Conclusion: Literature studies have several compounds that have the potential to be anti-inflammatory.</dc:description>
	<dc:publisher xml:lang="en">LPPM Universitas Jambi</dc:publisher>
	<dc:date>2025-11-26</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://online-journal.unja.ac.id/PROCA/article/view/50267</dc:identifier>
	<dc:identifier>10.22437/proca.v1i2.50267</dc:identifier>
	<dc:source xml:lang="en">Proceedings Academic Universitas Jambi; Vol. 1 No. 2 (2025): The 6th Jambi Medicine and Health Science International Conference (JAMHESIC); 443-451</dc:source>
	<dc:source>10.22437/proca.v1i2</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://online-journal.unja.ac.id/PROCA/article/view/50267/22603</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2025 Humaryanto, Fairuz, Fathnur Sani Kasmadi, Hanina, Tengku Arief Buana Perkasa</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by/4.0</dc:rights>
</oai_dc:dc>