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Patterns of guideline directed medical therapy (GDMT) in congestive heart failure patients at RSUD. Raden Mattaher Jambi

Proceedings Academic Universitas Jambi · Vol. 1 No. 2 (2025) · hlm. 860–868

DOI
10.22437/proca.v1i2.50457
Terbit
2025-11-30
Penerbit
LPPM Universitas Jambi
Bahasa
en
Lisensi
creativecommons.org/licenses/by/4.0

Abstrak

Background: Congestive heart failure (CHF) is a condition with a high mortality rate and a significant economic burden, requiring comprehensive and systematic therapeutic management. Guideline-Directed Medical Therapy (GDMT) recommends four pillars of therapy for patients with heart failure with reduced left ventricular ejection fraction: renin-angiotensin-aldosterone system (RAAS) inhibitors, beta-blockers, mineralocorticoid receptor antagonists (MRAs), and SGLT2 inhibitors, with diuretics used in certain conditions. Objective: This study aims to obtain a pattern of Guideline-Directed Medical Therapy (GDMT) in congestive heart failure patients at RSUD.Raden Matther Jamb Methods: This retrospective observational study describes the pattern of GDMT use in congestive heart failure patients at RSUD.Raden Matther Jambi during January–July 2025. Results: The results show that from 99 congestive heart failure patients, 70% received bisoprolol (beta-blocker), 34% received RAAS inhibitors (ACEi/ARB), and 4% received ARNI. MRAs were used by 27% of patients, and SGLT2 inhibitor use was not found. Conclusion: These findings indicate barriers to GDMT implementation related to healthcare financing policies, limited access to generic and innovator drugs, and patient adherence to therapeutic regimens.

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Sumber metadata: OAI-PMH (metadata jurnal) https://online-journal.unja.ac.id/index.php/PROCA/oai, pertama di-harvest 6 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">Patterns of guideline directed medical therapy (GDMT) in congestive heart failure patients at RSUD. Raden Mattaher Jambi</dc:title>
	<dc:creator xml:lang="en">Sadli, Nurul Kamilah</dc:creator>
	<dc:creator xml:lang="en">Perawati, Santi</dc:creator>
	<dc:creator xml:lang="en">Astuti, Novia Tri</dc:creator>
	<dc:creator xml:lang="en">Neldi, Vina</dc:creator>
	<dc:creator xml:lang="en">Astuti, Novia Tri</dc:creator>
	<dc:creator xml:lang="en">Pondawinata, Marizki</dc:creator>
	<dc:subject xml:lang="en">Congestive Heart Failure (CHF); Guideline-Directed Medical Therapy (GDMT); Drug Utilization Pattern; Beta-Blocker; Renin-Angiotensin-Aldosteron System (RAAS) Inhibitor; Mineralocorticoid Receptor Antagonists (MRA); Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i)</dc:subject>
	<dc:description xml:lang="en">Background: Congestive heart failure (CHF) is a condition with a high mortality rate and a significant economic burden, requiring comprehensive and systematic therapeutic management. Guideline-Directed Medical Therapy (GDMT) recommends four pillars of therapy for patients with heart failure with reduced left ventricular ejection fraction: renin-angiotensin-aldosterone system (RAAS) inhibitors, beta-blockers, mineralocorticoid receptor antagonists (MRAs), and SGLT2 inhibitors, with diuretics used in certain conditions. Objective: This study aims to obtain a pattern of Guideline-Directed Medical Therapy (GDMT) in congestive heart failure patients at RSUD.Raden Matther Jamb Methods: This retrospective observational study describes the pattern of GDMT use in congestive heart failure patients at RSUD.Raden Matther Jambi during January–July 2025. Results: The results show that from 99 congestive heart failure patients, 70% received bisoprolol (beta-blocker), 34% received RAAS inhibitors (ACEi/ARB), and 4% received ARNI. MRAs were used by 27% of patients, and SGLT2 inhibitor use was not found. Conclusion: These findings indicate barriers to GDMT implementation related to healthcare financing policies, limited access to generic and innovator drugs, and patient adherence to therapeutic regimens.</dc:description>
	<dc:publisher xml:lang="en">LPPM Universitas Jambi</dc:publisher>
	<dc:date>2025-11-30</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://online-journal.unja.ac.id/PROCA/article/view/50457</dc:identifier>
	<dc:identifier>10.22437/proca.v1i2.50457</dc:identifier>
	<dc:source xml:lang="en">Proceedings Academic Universitas Jambi; Vol. 1 No. 2 (2025): The 6th Jambi Medicine and Health Science International Conference (JAMHESIC); 860-868</dc:source>
	<dc:source>10.22437/proca.v1i2</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://online-journal.unja.ac.id/PROCA/article/view/50457/22691</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2025 Nurul Kamilah Sadli, Santi Perawati, Novia Tri Astuti, Vina Neldi, Novia Tri Astuti, Marizki Pondawinata</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by/4.0</dc:rights>
</oai_dc:dc>