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Characteristic of the neutrophil-to-lymphocyte ratio (NLR) in patients with chronic low back pain

Proceedings Academic Universitas Jambi · Vol. 1 No. 2 (2025) · hlm. 994–1000

DOI
10.22437/proca.v1i2.50525
Terbit
2025-11-30
Penerbit
LPPM Universitas Jambi
Bahasa
en
Lisensi
creativecommons.org/licenses/by/4.0

Abstrak

Background: Chronic low back pain (LBP) constitutes a worldwide public health issue that substantially impacts a considerable segment of the adult demographic. The Neutrophil-to-Lymphocyte Ratio (NLR) is recognized as a significant inflammatory biomarker for multiple health conditions, including musculoskeletal disorders like low back pain (LBP). Objective: The assessment of NLR in patients with LBP has aimed to identify a potential biomarker for elucidating the mechanisms underlying inflammation and chronic pain. Methods: This research is a cross-sectional analytical study. All samples in this study underwent a complete blood cell count examination. The neutrophil-to-lymphocyte ratio is calculated by dividing the neutrophil count by the lymphocyte count in routine blood test results. Statistical tests were conducted using SPSS software. Results: This study involved 31 participants. The analysis of the NLR indicated that 77.4% of participants were categorized as moderate, whereas 22.6% were classified as high. Furthermore, 18 individuals (58.06%) reported experiencing moderate pain (NPRS 4-6), while 13 individuals (41.94%) indicated severe pain (NPRS 7-10). Conclusion: This study found 77.4% of subjects had moderate NLR. Despite moderate to severe pain, their systemic inflammatory response had not fully established, as shown by a lack of NLR increase.

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Tia Wida EkaputriAfiliasi tidak diketahui3
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Mara Imam Taufiq SiregarUniversitas Jambi1
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Rita HalimUniversitas Jambi1
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Sumber metadata: OAI-PMH (metadata jurnal) https://online-journal.unja.ac.id/index.php/PROCA/oai, pertama di-harvest 6 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Characteristic of the neutrophil-to-lymphocyte ratio (NLR) in patients with chronic low back pain</dc:title>
	<dc:creator xml:lang="en">Istarini, Attiya</dc:creator>
	<dc:creator xml:lang="en">Lipinwati</dc:creator>
	<dc:creator xml:lang="en">Hanina</dc:creator>
	<dc:creator xml:lang="en">Justitia, Budi</dc:creator>
	<dc:creator xml:lang="en">Fitriyanti</dc:creator>
	<dc:subject xml:lang="en">Neutrophil-to-Lymphocyte Ratio (NLR); Chronic Low Back Pain (LBP); Inflammatory responses</dc:subject>
	<dc:description xml:lang="en">Background: Chronic low back pain (LBP) constitutes a worldwide public health issue that substantially impacts a considerable segment of the adult demographic. The Neutrophil-to-Lymphocyte Ratio (NLR) is recognized as a significant inflammatory biomarker for multiple health conditions, including musculoskeletal disorders like low back pain (LBP). Objective: The assessment of NLR in patients with LBP has aimed to identify a potential biomarker for elucidating the mechanisms underlying inflammation and chronic pain. Methods: This research is a cross-sectional analytical study. All samples in this study underwent a complete blood cell count examination. The neutrophil-to-lymphocyte ratio is calculated by dividing the neutrophil count by the lymphocyte count in routine blood test results. Statistical tests were conducted using SPSS software. Results: This study involved 31 participants. The analysis of the NLR indicated that 77.4% of participants were categorized as moderate, whereas 22.6% were classified as high. Furthermore, 18 individuals (58.06%) reported experiencing moderate pain (NPRS 4-6), while 13 individuals (41.94%) indicated severe pain (NPRS 7-10). Conclusion: This study found 77.4% of subjects had moderate NLR. Despite moderate to severe pain, their systemic inflammatory response had not fully established, as shown by a lack of NLR increase.</dc:description>
	<dc:publisher xml:lang="en">LPPM Universitas Jambi</dc:publisher>
	<dc:date>2025-11-30</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://online-journal.unja.ac.id/PROCA/article/view/50525</dc:identifier>
	<dc:identifier>10.22437/proca.v1i2.50525</dc:identifier>
	<dc:source xml:lang="en">Proceedings Academic Universitas Jambi; Vol. 1 No. 2 (2025): The 6th Jambi Medicine and Health Science International Conference (JAMHESIC); 994-1000</dc:source>
	<dc:source>10.22437/proca.v1i2</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://online-journal.unja.ac.id/PROCA/article/view/50525/22723</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2025 Attiya Istarini, Lipinwati, Hanina, Budi Justitia, Fitriyanti</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by/4.0</dc:rights>
</oai_dc:dc>