Melola Discovery

← Melola Discovery

Akses terbuka Jurnal

Potential Toxicity of Legundi Leaf Extract (Vitex Trifolia L) Using the Brine Shrimp Lethality Test (BSLT) Method

Journal of The Indonesian Society of Integrated Chemistry · Vol. 16 No. 1 (2024) · hlm. 21–28

DOI
10.22437/jisic.v16i1.33115
ISSN
2621-5543, 2085-1715
Terbit
2024-06-30
Penerbit
Pendidikan Kimia FKIP Universitas Jambi
Bahasa
en
Lisensi
creativecommons.org/licenses/by/4.0

Abstrak

Many natural products can be used as starting points in developing modern medicines because of their capabilities in pharmacological activities. Vitex trifolia L is an herbal plant that has been used to treat diseases such as fever, inflammation, colds, irregular menstruation, and diseases related to the female reproductive organs. This study aims to identify the cytotoxic ability of Vitex trifolia L leaf extract using the Brine Shrimp Lethality Test (BSLT) method. Extraction was carried out by maceration and fractionation methods, followed by phytochemical assay and cytotoxic assay using BSLT method. The results showed that the n-hexane extract had a moderate cytotoxic effect (LC50 241 µg/ml), the methanol extract included in the low toxic category (LC50 995 µg/ml) and the other two extracts involved in the non-toxic category (ethyl acetate and butanol).

Jaringan kolaborasi para penulis

28 penulis · 122 tautan kepenulisan bersama · 50 lintas organisasi

Arahkan kursor atau ketuk sebuah nama untuk menyorot rekan penulisnya. Klik dua kali untuk membuka halaman penulis.

  • Andalas University
  • IPB University
  • Diponegoro University
  • Bandung Institute of Technology
  • Padjadjaran University
  • Khairun University
  • Universitas Jambi
  • Afiliasi tidak diketahui
  • Organisasi berbeda
  • Organisasi sama
  • Afiliasi tidak diketahui
  • Garis lebih tebal = lebih banyak artikel bersama · lingkaran lebih besar = lebih banyak artikel
Tampilkan sebagai tabel
Rekan penulisOrganisasiArtikel bersama
Yulia Eka PutriAndalas University3
Syukri SyukriAndalas University2
Upita SeptianiAndalas University2
Kevin SeptiogaAndalas University1
Syukri AriefAndalas University1
Fadhil FerdianAndalas University1
Yetria RildaAndalas University1
Yosie AndrianiAfiliasi tidak diketahui1
Neviaty Putri ZamaniIPB University1
Elfahmi ElfahmiBandung Institute of Technology1
Inna Puspa AyuIPB University1
Beginer SubhanIPB University1
Lalu M. Iqbal SaniIPB University1
Novriyandi HanifIPB University1
Muhammad Hasan BashariPadjadjaran University1
Nebuchadnezzar AkbarKhairun University1
Ni Kadek Dita CahyaniDiponegoro University1
Dondy ArafatIPB University1
Siti Zanuba AisyahIPB University1
Emil SalimAndalas University1
Adlis SantoniAndalas University1
Melvi MuharmiUniversitas Jambi1
Tio Putra WendariAndalas University1
Retno Dyah WulandariAndalas University1
R. RefinelAndalas University1

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://online-journal.unja.ac.id/index.php/jisic/oai, pertama di-harvest 6 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Potential Toxicity of Legundi Leaf Extract (Vitex Trifolia L) Using the Brine Shrimp Lethality Test (BSLT) Method</dc:title>
	<dc:creator xml:lang="en">Arifah, Zil</dc:creator>
	<dc:creator xml:lang="en">Efdi, Mai</dc:creator>
	<dc:creator xml:lang="en">Syafrizayanti, Syafrizayanti</dc:creator>
	<dc:description xml:lang="en">Many natural products can be used as starting points in developing modern medicines because of their capabilities in pharmacological activities. Vitex trifolia L is an herbal plant that has been used to treat diseases such as fever, inflammation, colds, irregular menstruation, and diseases related to the female reproductive organs. This study aims to identify the cytotoxic ability of Vitex trifolia L leaf extract using the Brine Shrimp Lethality Test (BSLT) method. Extraction was carried out by maceration and fractionation methods, followed by phytochemical assay and cytotoxic assay using BSLT method. The results showed that the n-hexane extract had a moderate cytotoxic effect (LC50 241 µg/ml), the methanol extract included in the low toxic category (LC50 995 µg/ml) and the other two extracts involved in the non-toxic category (ethyl acetate and butanol).</dc:description>
	<dc:publisher xml:lang="en">Pendidikan Kimia FKIP Universitas Jambi</dc:publisher>
	<dc:date>2024-06-30</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://online-journal.unja.ac.id/jisic/article/view/33115</dc:identifier>
	<dc:identifier>10.22437/jisic.v16i1.33115</dc:identifier>
	<dc:source xml:lang="en">Journal of The Indonesian Society of Integrated Chemistry; Vol. 16 No. 1 (2024): Journal of The Indonesian Society of Integrated Chemistry; 21-28</dc:source>
	<dc:source>2621-5543</dc:source>
	<dc:source>2085-1715</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://online-journal.unja.ac.id/jisic/article/view/33115/18447</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2024 Zil Arifah, Mai Efdi1 &amp; Syafrizayanti</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by/4.0</dc:rights>
</oai_dc:dc>