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Analysis of Serum Glutamate Pyruvate Transaminase (SGPT) and Serum Glutamate Oxaloacetate Transaminase (SGOT) Levels in the Blood of Rat Offspring (Rattus norvegicus) Treated with Soybean (Glycine max L.) Extract and Zinc

Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan · Vol. 14 No. 1 (2026) · hlm. 31–37

DOI
10.22437/jmj.v14i1.41788
ISSN
2580-6874, 2339-269X
Terbit
2026-05-14
Penerbit
FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI
Bahasa
en

Abstrak

Background: The liver is the largest metabolic organ and plays an important role in the body. Nutritional fulfilment is one factor in maintaining liver health. Liver function can be evaluated by measuring the levels of SGPT and SGOT enzymes in the blood. Soybean juice and zinc can support liver health by keeping SGPT and SGOT enzyme levels normal. Methods: This study was conducted between October and December 2024 at the Zoology Laboratory of the University of Lampung. This study used a Completely Randomized Design (CRD) included four treatment groups. Each treatment included five mice: control (K), treatment 1 (P1)- induced Soybean juice 0,6 mL/kg body weight (P2) induced Soybean 0,3 mL/kg body weight and Zinc 0,3 mL/kg body weight, and (P3) induced Soybean 0,6 mL/kg body weight and Zinc 0,6 mL/kg body weight for 14 days. Normal and homogeneous data were analyzed using analysis of variance (ANOVA) to determine whether the treatment's effect was significant. Differences were considered statistically significant at p < 0.05. Duncan's multiple interval post hoc test (=5%) was used to identify the most effective treatment. Result: Based on the results of the one-way ANOVA test with a 95% confidence interval, the average SGPT and SGOT levels in the K, P1, P2, and P3 treatments differ significantly. The average SGPT levels above show that the P2 and P3 groups experienced a significant decrease compared to the K and P1 treatments. Conclusion: Analysis of variance (ANOVA) showed that administering soya juice and zinc at an optimum dose of 1.2 mL/kg body weight can affect and maintain normal SGPT and SGOT levels.

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13 penulis · 51 tautan kepenulisan bersama · 1 lintas organisasi

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  • Lampung University
  • Universitas Muslim Indonesia
  • Afiliasi tidak diketahui
  • Organisasi berbeda
  • Organisasi sama
  • Afiliasi tidak diketahui
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Rekan penulisOrganisasiArtikel bersama
Sulastri SulastriUniversitas Muslim Indonesia1
Muhammad Al-HafidzAfiliasi tidak diketahui1
Yuniastini YuniastiniLampung University1
Purwati PurwatiAfiliasi tidak diketahui1
Antun RahmadiAfiliasi tidak diketahui1
Wien WiratmokoAfiliasi tidak diketahui1
Iradah Lia PrasetioAfiliasi tidak diketahui1
Fannia Khairani MzAfiliasi tidak diketahui1
Mohammad Hafid HakAfiliasi tidak diketahui1

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://online-journal.unja.ac.id/index.php/kedokteran/oai, pertama di-harvest 6 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Analysis of Serum Glutamate Pyruvate Transaminase (SGPT) and Serum Glutamate Oxaloacetate Transaminase (SGOT) Levels in the Blood of Rat Offspring (Rattus norvegicus) Treated with Soybean (Glycine max L.) Extract and Zinc</dc:title>
	<dc:creator xml:lang="en">Hafidz, Muhammad Al Hafidz</dc:creator>
	<dc:creator xml:lang="en">Busman, Hendri</dc:creator>
	<dc:creator xml:lang="en">Kanedi, M. Kanedi</dc:creator>
	<dc:creator xml:lang="en">Widiastuti, Endang Linirin</dc:creator>
	<dc:subject xml:lang="en">Liver</dc:subject>
	<dc:subject xml:lang="en">SGPT</dc:subject>
	<dc:subject xml:lang="en">SGOT</dc:subject>
	<dc:subject xml:lang="en">Soyabean</dc:subject>
	<dc:subject xml:lang="en">Zinc</dc:subject>
	<dc:description xml:lang="en">Background: The liver is the largest metabolic organ and plays an important role in the body. Nutritional fulfilment is one factor in maintaining liver health. Liver function can be evaluated by measuring the levels of SGPT and SGOT enzymes in the blood. Soybean juice and zinc can support liver health by keeping SGPT and SGOT enzyme levels normal.
Methods: This study was conducted between October and December 2024 at the Zoology Laboratory of the University of Lampung. This study used a Completely Randomized Design (CRD) included four treatment groups. Each treatment included five mice: control (K), treatment 1 (P1)- induced Soybean juice 0,6 mL/kg body weight (P2) induced Soybean 0,3 mL/kg body weight and Zinc 0,3 mL/kg body weight, and (P3) induced Soybean 0,6 mL/kg body weight and Zinc 0,6 mL/kg body weight for 14 days. Normal and homogeneous data were analyzed using analysis of variance (ANOVA) to determine whether the treatment's effect was significant. Differences were considered statistically significant at p &amp;lt; 0.05. Duncan's multiple interval post hoc test (=5%) was used to identify the most effective treatment.
Result: Based on the results of the one-way ANOVA test with a 95% confidence interval, the average SGPT and SGOT levels in the K, P1, P2, and P3 treatments differ significantly. The average SGPT levels above show that the P2 and P3 groups experienced a significant decrease compared to the K and P1 treatments.
Conclusion: Analysis of variance (ANOVA) showed that administering soya juice and zinc at an optimum dose of 1.2 mL/kg body weight can affect and maintain normal SGPT and SGOT levels.</dc:description>
	<dc:publisher xml:lang="en">FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI</dc:publisher>
	<dc:date>2026-05-14</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://online-journal.unja.ac.id/kedokteran/article/view/41788</dc:identifier>
	<dc:identifier>10.22437/jmj.v14i1.41788</dc:identifier>
	<dc:source xml:lang="en">Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan; Vol. 14 No. 1 (2026): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan; 31-37</dc:source>
	<dc:source>2580-6874</dc:source>
	<dc:source>2339-269X</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://online-journal.unja.ac.id/kedokteran/article/view/41788/24311</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2026 Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan</dc:rights>
</oai_dc:dc>