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IN VITRO PHARMACOLOGICAL ACTIVITY TEST OF TELANG FLOWER KOMBUCHA AS ANTIBACTERIAL Vibrio Cholerae AND Shigella dysenteriae THROUGH FERMENTATION BIOTECHNOLOGY METHOD

BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan · Vol. 11 No. 2 (2025) · hlm. 130–146

DOI
10.22373/biotik.v11i2.17427
ISSN
2549-1768, 2337-9812
Terbit
2025-09-23
Penerbit
Universitas Islam Negeri Ar-Raniry
Bahasa
eng
Lisensi
creativecommons.org/licenses/by-sa/4.0

Abstrak

Diarrhea that occurs in the digestive tract is a big problem for human intestinal health. This can be caused by the activity of pathogenic bacteria in the form of Vibrio cholera and Shigella dysinteriae. In this study, kombucha has been shown to have pharmacological activity in vitro in inhibiting the growth of Vibrio cholera and Shigella dysinteriae bacteria at all sugar concentrations. The purpose of this study was to determine the in vitro pharmacological activity of the butterfly pea flower kombucha in inhibiting the growth of the two test bacteria consisting of a sugar concentration of 20%, 30% and 40%. The method for testing the inhibition of both bacterial growth tests is disc diffusion. One way ANOVA and post hoc analysis are one of the quantitative test methods used in this study of the average diameter of the inhibition zone of teal flower kombucha from various sugar concentrations. The results of this study have proven based on a one-way ANOVA with each P value> 0.05 and then continued through post hoc analysis concluded that the telang flower kombucha at a concentration of 40% is the best treatment in inhibiting the growth of both test bacteria where the concentration is significantly different from sugar concentration 20% and 30%.

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  • Universitas Sembilanbelas November Kolaka
  • Institut Kesehatan Helvetia
  • Insitut Kesehatan Immanuel
  • Universitas Jambi
  • Universitas Mathla'ul Anwar Banten
  • Diponegoro University
  • National Research and Innovation Agency
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Rekan penulisOrganisasiArtikel bersama
Hari HariadiNational Research and Innovation Agency4
Ayu SafitriTanjungpura University2
Barolym Tri PamungkasMulawarman University2
Muhammad AndryInstitut Kesehatan Helvetia2
Lucky Dita AgustiansyahAfiliasi tidak diketahui2
Fajar HidayantoUniversitas Merdeka Pasuruan2
Agusriyadin AgusriyadinUniversitas Sembilanbelas November Kolaka1
La Ode Abdul Fajar HasiduUniversitas Sembilanbelas November Kolaka1
Akhmad Fadli IbrahimUniversitas Sembilanbelas November Kolaka1
Arif Eka PrasetyaUniversitas Sembilanbelas November Kolaka1
Asni AsniAfiliasi tidak diketahui1
Azhar Aras MubarakUniversitas Sembilanbelas November Kolaka1
Sudarwin KamurUniversitas Sembilanbelas November Kolaka1
Gaby Nanda KharismaUniversitas Sembilanbelas November Kolaka1
Edwin PermanaUniversitas Jambi1
Dhian Eka WijayaUniversitas Jambi1
Martina Asti RahayuUniversitas Jambi1
Moh NabawiUniversitas Jambi1
Afrimanisa AfrimanisaAfiliasi tidak diketahui1
Boima SitumeangPadjadjaran University1
Muhammad Mutfi Amin ShidqiAfiliasi tidak diketahui1
Khairani FitriInstitut Kesehatan Helvetia1
Tetty Noverita KhairaniInstitut Kesehatan Helvetia1
Muhammad AndryInstitut Kesehatan Helvetia1
Muhammad Amin NasutionUniversitas Muslim Nusantara Al Washliyah1
Muhammad Fauzan LubisUniversitas Sumatera Utara1
Jashima UkhtiaInstitut Kesehatan Helvetia1
Asysyifa RianaInsitut Kesehatan Immanuel1
Yuliati WidiastutiInsitut Kesehatan Immanuel1
Iriyanti HarunInsitut Kesehatan Immanuel1
Galuh Chandra IrawanDiponegoro University1
Lanny TantieInsitut Kesehatan Immanuel1
Kartika AnzaniInsitut Kesehatan Immanuel1
Andri Tri CahyonoAfiliasi tidak diketahui1

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Sumber metadata: OAI-PMH (metadata jurnal) https://jurnal.ar-raniry.ac.id/index.php/biotik/oai, pertama di-harvest 6 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">IN VITRO PHARMACOLOGICAL ACTIVITY TEST OF TELANG FLOWER KOMBUCHA AS ANTIBACTERIAL Vibrio Cholerae AND Shigella dysenteriae THROUGH FERMENTATION BIOTECHNOLOGY METHOD</dc:title>
	<dc:creator xml:lang="en">Somantri, Ucu Wandi</dc:creator>
	<dc:creator xml:lang="en">Fadillah, M Fariz</dc:creator>
	<dc:creator xml:lang="en">Rezaldi, Firman</dc:creator>
	<dc:creator xml:lang="en">Pruschia, Isti Dwi</dc:creator>
	<dc:creator xml:lang="en">Margarisa, Dwiyarina</dc:creator>
	<dc:creator xml:lang="en">Maharani, Maharani</dc:creator>
	<dc:subject xml:lang="en">Kombucha</dc:subject>
	<dc:subject xml:lang="en">Telang Flower</dc:subject>
	<dc:subject xml:lang="en">Vibrio cholerae</dc:subject>
	<dc:subject xml:lang="en">Shigella dysenteriae</dc:subject>
	<dc:description xml:lang="en">Diarrhea that occurs in the digestive tract is a big problem for human intestinal health. This can be caused by the activity of pathogenic bacteria in the form of Vibrio cholera and Shigella dysinteriae. In this study, kombucha has been shown to have pharmacological activity in vitro in inhibiting the growth of Vibrio cholera and Shigella dysinteriae bacteria at all sugar concentrations. The purpose of this study was to determine the in vitro pharmacological activity of the butterfly pea flower kombucha in inhibiting the growth of the two test bacteria consisting of a sugar concentration of 20%, 30% and 40%. The method for testing the inhibition of both bacterial growth tests is disc diffusion. One way ANOVA and post hoc analysis are one of the quantitative test methods used in this study of the average diameter of the inhibition zone of teal flower kombucha from various sugar concentrations. The results of this study have proven based on a one-way ANOVA with each P value&amp;gt; 0.05 and then continued through post hoc analysis concluded that the telang flower kombucha at a concentration of 40% is the best treatment in inhibiting the growth of both test bacteria where the concentration is significantly different from sugar concentration 20% and 30%.</dc:description>
	<dc:publisher xml:lang="en">Universitas Islam Negeri Ar-Raniry</dc:publisher>
	<dc:date>2025-09-23</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:format>application/vnd.openxmlformats-officedocument.wordprocessingml.document</dc:format>
	<dc:identifier>https://jurnal.ar-raniry.ac.id/index.php/biotik/article/view/17427</dc:identifier>
	<dc:identifier>10.22373/biotik.v11i2.17427</dc:identifier>
	<dc:source xml:lang="en">BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan; Vol. 11 No. 2 (2023): JURNAL BIOTIK; 130-146</dc:source>
	<dc:source xml:lang="id">Biotik; Vol 11 No 2 (2023): JURNAL BIOTIK; 130-146</dc:source>
	<dc:source>2549-1768</dc:source>
	<dc:source>2337-9812</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://jurnal.ar-raniry.ac.id/index.php/biotik/article/view/17427/pdf</dc:relation>
	<dc:relation>https://jurnal.ar-raniry.ac.id/index.php/biotik/article/view/17427/11343</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2023 firman rezaldi</dc:rights>
	<dc:rights xml:lang="en">http://creativecommons.org/licenses/by-sa/4.0</dc:rights>
</oai_dc:dc>