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A Turn-off Fluorescent Chemosensor for Detecting Formaldehyde Based on Pyridine Derivative

al Kimiya: Jurnal Ilmu Kimia dan Terapan · Vol. 10 No. 2 (2023) · pp. 107–113

DOI
10.15575/ak.v10i2.25573
ISSN
2407-1927, 2407-1897
Published
2023-12-31
Publisher
Department of Chemistry, Faculty of Science and Technology, UIN Sunan Gunung Djati Bandung
Language
eng

Abstract

Formaldehyde in solution, commonly known as formalin, is often utilized. In Indonesia, there is widespread misuse of formalin as a food preservative. Formaldehyde has been identified as a carcinogenic substance by the International Agency for Research on Cancer (IARC) and the Environmental Protection Agency (EPA). Based on this background, the present study developed a sensor compound capable of detecting formaldehyde obviously. The compound 3'-(4-(3,4-dimethoxyphenyl)pyridine-2,6-diyl)dianiline (ChP-2A) has been successfully synthesized through the reduction reaction of the compound 4-(3,4-dimethoxyphenyl)-2,6-bis(3-nitrophenyl)pyridine (ChP-0A) using 80% hydrazine hydrate and 10% Pd/C as a catalyst. The ChP-2A compound in acetonitrile exhibits a significant decrease in fluorescence intensity (turn-off) after the addition of formaldehyde, and it has been successfully applied in the form of a test paper for the detection of formaldehyde qualitatively

Keywords

Collaboration network of the authors

40 authors · 128 co-authorship links · 1 across different organisations · showing the 40 most connected

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

  • Hasanuddin University
  • Institut Teknologi Kalimantan
  • Universitas Sulawesi Barat
  • State University of Semarang
  • University of Indonesia
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Agung PutraAffiliation unknown5
Iffan AlifAffiliation unknown2
Titiek SumarawatiAffiliation unknown2
Salma Yasmine AzzaharaAffiliation unknown2
Destyariani Liana PutriInstitut Teknologi Kalimantan1
Muhammad Khaisar WirawanInstitut Teknologi Kalimantan1
Nurul HidayahInstitut Teknologi Kalimantan1
Siti SulemanAffiliation unknown1
Andhika Hayyu PratamaAffiliation unknown1
Fabelyn Gandryal MistipaAffiliation unknown1
Muhammad Fakhri ArdyansyahAffiliation unknown1
Hans Julio PratamaAffiliation unknown1
Fabelyn Gandryal Mistipa AvinHasanuddin University1
Siti Arifaini SulemanHasanuddin University1
Andhika Hayyu PratamaHasanuddin University1
Muhammad Fakhri ArdyansyahHasanuddin University1
Nurul HidayahHasanuddin University1
Hans Julio PratamaHasanuddin University1
Nurfadilah NurfadilahHasanuddin University1
Haris HarisUniversitas Sulawesi Barat1
Dinil QaiyimahAffiliation unknown1
Misdar AmdahAffiliation unknown1
Mulianti MuliantiAffiliation unknown1
Nasrul NasrulAffiliation unknown1
As'adi AbdullahAffiliation unknown1
Elis TambaruHasanuddin University1
Ari YuniastutiState University of Semarang1
Edi WaluyoAffiliation unknown1
Wisnu SunartoAffiliation unknown1
Sri WardaniAffiliation unknown1
Siti NurrohmahUniversity of Indonesia1
Rodia SyamwilAffiliation unknown1
Mohamad MuspawiAffiliation unknown1
Firman FirmanHasanuddin University1
Arda Trisnawaty PanjaitanAffiliation unknown1
Fanny Angelika ManullangAffiliation unknown1
Friska Mawira ManullangAffiliation unknown1
Widya Patricia Utama NahampunAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.uinsgd.ac.id/index.php/ak/oai, first harvested 7 Nov 2026, last seen 8 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">A Turn-off Fluorescent Chemosensor for Detecting Formaldehyde Based on Pyridine Derivative</dc:title>
	<dc:creator>Hidayah, Nurul</dc:creator>
	<dc:creator>Purwono, Bambang</dc:creator>
	<dc:subject xml:lang="en-US">Pyridine</dc:subject>
	<dc:subject xml:lang="en-US">Formaldehyde</dc:subject>
	<dc:subject xml:lang="en-US">Fluorescence</dc:subject>
	<dc:subject xml:lang="en-US">Turn-off</dc:subject>
	<dc:subject xml:lang="en-US">Formalin</dc:subject>
	<dc:description xml:lang="en-US">Formaldehyde in solution, commonly known as formalin, is often utilized. In Indonesia, there is widespread misuse of formalin as a food preservative. Formaldehyde has been identified as a carcinogenic substance by the International Agency for Research on Cancer (IARC) and the Environmental Protection Agency (EPA). Based on this background, the present study developed a sensor compound capable of detecting formaldehyde obviously. The compound 3'-(4-(3,4-dimethoxyphenyl)pyridine-2,6-diyl)dianiline (ChP-2A) has been successfully synthesized through the reduction reaction of the compound 4-(3,4-dimethoxyphenyl)-2,6-bis(3-nitrophenyl)pyridine (ChP-0A) using 80% hydrazine hydrate and 10% Pd/C as a catalyst. The ChP-2A compound in acetonitrile exhibits a significant decrease in fluorescence intensity (turn-off) after the addition of formaldehyde, and it has been successfully applied in the form of a test paper for the detection of formaldehyde qualitatively</dc:description>
	<dc:publisher xml:lang="en-US">Department of Chemistry, Faculty of Science and Technology, UIN Sunan Gunung Djati Bandung</dc:publisher>
	<dc:date>2023-12-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/vnd.openxmlformats-officedocument.wordprocessingml.document</dc:format>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.uinsgd.ac.id/index.php/ak/article/view/25573</dc:identifier>
	<dc:identifier>10.15575/ak.v10i2.25573</dc:identifier>
	<dc:source xml:lang="en-US">al Kimiya: Jurnal Ilmu Kimia dan Terapan; Vol. 10 No. 2 (2023): al Kimiya: Jurnal Ilmu Kimia dan Terapan; 107-113</dc:source>
	<dc:source>2407-1927</dc:source>
	<dc:source>2407-1897</dc:source>
	<dc:source>10.15575/ak.v10i2</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journal.uinsgd.ac.id/index.php/ak/article/view/25573/13240</dc:relation>
	<dc:relation>https://journal.uinsgd.ac.id/index.php/ak/article/view/25573/10225</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2023 Nurul Hidayah</dc:rights>
</oai_dc:dc>