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Journal SINTA 1

Reactivation of Hepatitis B Virus Associated with Chemotherapy and Immunosuppressive Agent

ACTA MEDICA INDONESIANA · Vol. 45 No. 1 (2013)

ISSN
2338-2732, 0125-9326
Published
2013-01-01
Publisher
The Indonesian Society of Internal Medicine
Language
eng

Abstract

Hepatitis B virus (HBV) reactivation after chemotherapy or immunosuppressive therapy is a serious cause of liver-related morbidity and mortality. The mechanism of HBV reactivation is still unclear, but it is believed due to the suppression of immune response hence increasing the viral load. No uniform diagnostic criteria are available, HBV reactivation can be confirmed by an increase in serum HBV-DNA level. There are many consensus regarding this issue, including the type and duration of nucleoside analogue therapy which need to be understood as not all chronic hepatitis B patients will lead to HBV reactivation. Recently, there has been an increased awareness of reactivation of occult hepatitis B virus, especially in hepatitis B virus endemic area, including Indonesia as part of Asia Pacific region. Preempative antiviral therapy was the best approach to prevent the HBV reactivation. Key words: hepatitis B virus reactivation, chemotherapy, immunosuppressive

Collaboration network of the authors

40 authors · 146 co-authorship links · showing the 40 most connected

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

  • Universitas Halu Oleo
  • University of Indonesia
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Juferdy KurniawanAffiliation unknown8
Rino Alvani GaniAffiliation unknown5
Laniyati HamijoyoAffiliation unknown4
Andri SanityosoAffiliation unknown3
Cosmas Rinaldi A LesmanaAffiliation unknown3
Chyntia Olivia Maurine JasirwanAffiliation unknown3
Kemal Fariz KalistaAffiliation unknown3
Andri Sanityoso SulaimanAffiliation unknown3
Ikhwan RinaldiAffiliation unknown3
Gita ApriliciaAffiliation unknown3
Rino A GaniAffiliation unknown2
Hamzah ShatriAffiliation unknown2
Siti SetiatiAffiliation unknown2
Guntur DarmawanAffiliation unknown2
Andhika RachmanAffiliation unknown2
Ratna SupiyahUniversitas Halu Oleo1
Suharty RoslanUniversitas Halu Oleo1
Rosa LesmanaAffiliation unknown1
Efa Ayu NabilaAffiliation unknown1
Harry AgustianAffiliation unknown1
Sipah AudiahAffiliation unknown1
Adam FaturahmanAffiliation unknown1
Maulana SuryaminAffiliation unknown1
C. Rinaldi A LesmanaAffiliation unknown1
Parlindungan SiregarAffiliation unknown1
Felix F WidjajaAffiliation unknown1
Paramita KhairanAffiliation unknown1
Telly KameliaAffiliation unknown1
Marcellus SimadibrataAffiliation unknown1
Em YunirUniversity of Indonesia1
Dharmeizar DharmeizarAffiliation unknown1
Ika Prasetya WijayaAffiliation unknown1
Winfrey PangestuAffiliation unknown1
Lutfie LutfieAffiliation unknown1
Ignatius Bima PrasetyaAffiliation unknown1
Wismandari WisnuAffiliation unknown1
Cleopas Martin RumendeAffiliation unknown1
Trinugroho Heri FadjariAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) http://www.actamedindones.org/index.php/ijim/oai, first harvested 8 Nov 2026, last seen 8 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">Reactivation of Hepatitis B Virus Associated with Chemotherapy and Immunosuppressive Agent</dc:title>
	<dc:creator>Wijaya, Indra</dc:creator>
	<dc:creator>Hasan, Irsan</dc:creator>
	<dc:description xml:lang="en-US">Hepatitis B virus (HBV) reactivation after chemotherapy or immunosuppressive therapy is a serious cause of liver-related morbidity and mortality. The mechanism of HBV reactivation is still unclear, but it is believed due to the suppression of immune response hence increasing the viral load. No uniform diagnostic criteria are available, HBV reactivation can be confirmed by an increase in serum HBV-DNA level. There are many consensus regarding this issue, including the type and duration of nucleoside analogue therapy which need to be understood as not all chronic hepatitis B patients will lead to HBV reactivation. Recently, there has been an increased awareness of reactivation of occult hepatitis B virus, especially in hepatitis B virus endemic area, including Indonesia as part of Asia Pacific region. Preempative antiviral therapy was the best approach to prevent the HBV reactivation. Key words: hepatitis B virus reactivation, chemotherapy, immunosuppressive</dc:description>
	<dc:publisher xml:lang="en-US">The Indonesian Society of Internal Medicine</dc:publisher>
	<dc:date>2013-01-01</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://www.actamedindones.org/index.php/ijim/article/view/123</dc:identifier>
	<dc:source xml:lang="en-US">Acta Medica Indonesiana; Vol. 45 No. 1 (2013)</dc:source>
	<dc:source>2338-2732</dc:source>
	<dc:source>0125-9326</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://www.actamedindones.org/index.php/ijim/article/view/123/118</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2016 Indonesian Journal of internal Medicine</dc:rights>
</oai_dc:dc>