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Exercise Intervention for Chronic Pain Management, Muscle Strengthening, and Functional Score in Obese Patients with Chronic Musculoskeletal Pain: A Systematic Review and Meta-analysis

ACTA MEDICA INDONESIANA · Vol. 50 No. 4 (2019)

ISSN
2338-2732, 0125-9326
Published
2019-01-11
Publisher
The Indonesian Society of Internal Medicine
Language
eng

Abstract

Background: obesity and osteoarthritis have strong inter-relationship with multi-factorial mechanism that caused pain and leads to decreased quality of life. Exercise has been identified as prevention and management against obesity and joint pain. This systematic review aims to assess the effect between exercises compared to diet group for chronic pain management, physical and mental function in obese patients with chronic musculoskeletal problem. Methods: we performed a systematic search of Randomized Control Trial studies from Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE; EBSCO; SCIENCEDIRECT (Elsevier); SCOPUS, grey literature, trial registry, ongoing study for published studies, and from the ClinicalTrial.gov, thesis of rehabilitation medicine in RSCM, and proceeding books for unpublished studies that was last updated on November 2016. Risk of bias was assessed using Cochrane risk-of-bias tool and data were analyzed using Review Manager 2014. Results: one study showed no difference in pain reduction (assessed using VAS) between two groups. Two studies showed improvement in physical function measured using 6MWT in exercise group at 6 and 18 months with mean difference 28.12 [11.20, 45.04] and 26.21 [9.01, 43.41]. There was no significant effects observed for Mental and Physical Function based on SF-36 after 6 months (1 study) and 18 months (2 studies) observation, with mean difference 1.10 [-0.79, 2.99] and 0.08 [-1.53, 1.70] respectively for Mental Function score and -0.30 [-2.54, 1.94] and -0.36 [-2.30, 1.57] respectively for Physical Function score. Conclusion: exercise can improve physical function objectively, but could not reduce pain in obese patients with chronic musculoskeletal problem subjectively.

Keywords

Collaboration network of the authors

38 authors · 139 co-authorship links

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  • Institut Teknologi Sepuluh Nopember
  • Affiliation unknown
  • Different organisations
  • Same organisation
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Co-authorOrganisationJoint articles
Siti SetiatiAffiliation unknown4
Kuntjoro HarimurtiAffiliation unknown2
Andwi Setiawan KokokAffiliation unknown2
Indah Suci WidyaheningAffiliation unknown2
Arief KurniawanInstitut Teknologi Sepuluh Nopember1
Ikhwanuliman PuteraAffiliation unknown1
M. Gema RamadhanAffiliation unknown1
Shafira AnindyaAffiliation unknown1
Natalia R SutantoAffiliation unknown1
F. Nikodemus HoseaAffiliation unknown1
Purwita W LaksmiAffiliation unknown1
Euphemia SetoAffiliation unknown1
F.H. IdrisAffiliation unknown1
M. MansyurAffiliation unknown1
Sidartawan SoegondoAffiliation unknown1
Pradana SoewondoAffiliation unknown1
Joedo PrihartonoAffiliation unknown1
Nafrialdi NafrialdiAffiliation unknown1
Purwita Wijaya LaksmiAffiliation unknown1
Wasilah RochmahAffiliation unknown1
Muhammad K AzwarAffiliation unknown1
Eka Dian SafitriAffiliation unknown1
Respati W RanakusumaAffiliation unknown1
Siti Rizny F SaldiAffiliation unknown1
Jessica MarsigitAffiliation unknown1
Widyaningsih WidyaningsihAffiliation unknown1
Dyah PurnamasariAffiliation unknown1
Alida R HarahapAffiliation unknown1
Noto DwimartutieAffiliation unknown1
Ani Retno PrijantiAffiliation unknown1
I Dewa Putu PramantaraAffiliation unknown1
Maria Regina RachmawatiAffiliation unknown1
Binar SasonoAffiliation unknown1
Melinda HariniAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) http://www.actamedindones.org/index.php/ijim/oai, first harvested 8 Nov 2026, last seen 8 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">Exercise Intervention for Chronic Pain Management, Muscle Strengthening, and Functional Score in Obese Patients with Chronic Musculoskeletal Pain: A Systematic Review and Meta-analysis</dc:title>
	<dc:creator>Tamin, Tirza Z</dc:creator>
	<dc:creator>Murdana, Nyoman</dc:creator>
	<dc:creator>Pitoyo, Yupitri</dc:creator>
	<dc:creator>Safitri, Eka D</dc:creator>
	<dc:subject xml:lang="en-US">Exercises intervention</dc:subject>
	<dc:subject xml:lang="en-US">Chronic pain management</dc:subject>
	<dc:subject xml:lang="en-US">Functional score</dc:subject>
	<dc:subject xml:lang="en-US">Quality of life</dc:subject>
	<dc:subject xml:lang="en-US">Systematic review</dc:subject>
	<dc:subject xml:lang="en-US">rheumatology</dc:subject>
	<dc:description xml:lang="en-US">Background: obesity and osteoarthritis have strong inter-relationship with multi-factorial mechanism that caused pain and leads to decreased quality of life. Exercise has been identified as prevention and management against obesity and joint pain. This systematic review aims to assess the effect between exercises compared to diet group for chronic pain management, physical and mental function in obese patients with chronic musculoskeletal problem. Methods: we performed a systematic search of Randomized Control Trial studies from Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE; EBSCO; SCIENCEDIRECT (Elsevier); SCOPUS, grey literature, trial registry, ongoing study for published studies, and from the ClinicalTrial.gov, thesis of rehabilitation medicine in RSCM, and proceeding books for unpublished studies that was last updated on November 2016. Risk of bias was assessed using Cochrane risk-of-bias tool and data were analyzed using Review Manager 2014. Results: one study showed no difference in pain reduction (assessed using VAS) between two groups. Two studies showed improvement in physical function measured using 6MWT in exercise group at 6 and 18 months with mean difference 28.12 [11.20, 45.04] and 26.21 [9.01, 43.41]. There was no significant effects observed for Mental and Physical Function based on SF-36 after 6 months (1 study) and 18 months (2 studies) observation, with mean difference 1.10 [-0.79, 2.99] and 0.08 [-1.53, 1.70] respectively for Mental Function score and -0.30 [-2.54, 1.94]  and -0.36 [-2.30, 1.57] respectively for Physical Function score. Conclusion: exercise can improve physical function objectively, but could not reduce pain in obese patients with chronic musculoskeletal problem subjectively.</dc:description>
	<dc:publisher xml:lang="en-US">The Indonesian Society of Internal Medicine</dc:publisher>
	<dc:date>2019-01-11</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US">systematic review and meta analysis, randomized control trial study</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://www.actamedindones.org/index.php/ijim/article/view/854</dc:identifier>
	<dc:source xml:lang="en-US">Acta Medica Indonesiana; Vol. 50 No. 4 (2018): Acta Medica Indonesiana; 299</dc:source>
	<dc:source>2338-2732</dc:source>
	<dc:source>0125-9326</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://www.actamedindones.org/index.php/ijim/article/view/854/pdf</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2019 Acta Medica Indonesiana</dc:rights>
</oai_dc:dc>