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Factors Associated with Mortality of Intensive Care Unit Patients with Acute Kidney Injury at Cipto Mangunkusumo National Central General Hospital

ACTA MEDICA INDONESIANA · Vol. 51 No. 4 (2020)

ISSN
2338-2732, 0125-9326
Published
2020-02-10
Publisher
The Indonesian Society of Internal Medicine
Language
eng

Abstract

Background: the incidence of acute kidney injury (AKI) in intensive care units is associated with increased mortality, post AKI morbidity and high treatment costs. Research on factors related to mortality of AKI patients in intensive care units in Indonesia, especially Cipto Mangungkusumo General Hospital has never been done. This study aims to determine the prevalence of AKI, mortality rate of AKI patients, and the factors associated with increased mortality of AKI patients in intensive care units in ICU Cipto Mangunkusumo General Hospital. Methods: this is a retrospective cohort study of all patients diagnosed with AKI in the intensive care unit at Cipto Mangunkusumo General Hospital, January 2015 - December 2016. An analysis of bivariate relationships with multvariate with STATA Statistics 15.0 between age > 60 years, sepsis, use of ventilator, ventilator duration, dialysis, oligoanuria, and APACHE II scores at admission with mortality. Results: the prevalence of AKI patients in the intensive care unit was 12.25% (675 of 5511 subjects) and 220 subjects (32.59%) of the 675 analyzed subjects died in the intensive care unit. Factors related to increased mortality in multivariate analysis were sepsis (OR 6,174; IK95% 3,116-12,233), oligoanuria (OR 4,173; IK95% 2,104-8,274), use of ventilator (OR 3,085; IK95% 1,348-7,057), (scores APACHE II at admission) 1/2 [OR 1,597; IK95% 1.154-2.209], and the duration of the ventilator (OR 1.062; IK95% 1.012-1.114). Conclusion: the prevalence of AKI patients and their mortality rate in the intensive care unit of Cipto Mangunkusumo General Hospital obtained 12.25% and 32.59%. Sepsis, oligoanuria, ventilators (APACHE II score at admission) 1/2, and ventilator duration are factors that are significantly associated with increased mortality of AKI patients in intensive care units.

Keywords

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40 authors · 161 co-authorship links · showing the 40 most connected

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Co-authorOrganisationJoint articles
Idrus AlwiAffiliation unknown5
Kuntjoro HarimurtiAffiliation unknown4
Eka GinanjarAffiliation unknown4
Siti SetiatiAffiliation unknown3
Pringgodigdo NugrohoAffiliation unknown3
Hamzah ShatriAffiliation unknown2
Muhammad YaminAffiliation unknown2
Taufik IndrajayaAffiliation unknown2
Sally Aman NasutionAffiliation unknown2
Dita AditianingsihAffiliation unknown2
Dyah PurnamasariAffiliation unknown1
Ahmad Fariz M.Z ZeinAffiliation unknown1
Sally A NasutionAffiliation unknown1
Purwantyastuti PurwantyastutiAffiliation unknown1
Gestina AliskaAffiliation unknown1
Rianto SetiabudiAffiliation unknown1
Anis KaruniawatiAffiliation unknown1
Trisni U DewiAffiliation unknown1
Muhammad K AzwarAffiliation unknown1
Riadi WirawanAffiliation unknown1
Ailinda Theodora TedjaAffiliation unknown1
Fify HenrikaAffiliation unknown1
Esthika DewiastyAffiliation unknown1
Aulia RizkaAffiliation unknown1
Dharmeizar DharmeizarAffiliation unknown1
Mita Hafsah SaraswatiAffiliation unknown1
Meilania SaraswatiAffiliation unknown1
Suzanna ImmanuelAffiliation unknown1
Ikhwan RinaldiAffiliation unknown1
Muhadi MuhadiAffiliation unknown1
Rasco Sandy SihombingAffiliation unknown1
Suhardjono SuhardjonoAffiliation unknown1
Dimas PriantonoAffiliation unknown1
Ketut SuastikaAffiliation unknown1
Pranawa MartosuwignjoAffiliation unknown1
Roy Panusunan SibaraniAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) http://www.actamedindones.org/index.php/ijim/oai, first harvested 8 Nov 2026, last seen 8 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Factors Associated with Mortality of Intensive Care Unit Patients with Acute Kidney Injury at Cipto Mangunkusumo National Central General Hospital</dc:title>
	<dc:creator>Lydia, Aida</dc:creator>
	<dc:creator>Rebecca, Ruth V</dc:creator>
	<dc:creator>Sedono, Rudyanto</dc:creator>
	<dc:creator>Mansjoer, Arif</dc:creator>
	<dc:subject xml:lang="en-US">acute kidney injury</dc:subject>
	<dc:subject xml:lang="en-US">risk factors</dc:subject>
	<dc:subject xml:lang="en-US">intensive care unit</dc:subject>
	<dc:subject xml:lang="en-US">mortality</dc:subject>
	<dc:description xml:lang="en-US">Background: the incidence of acute kidney injury (AKI) in intensive care units is associated with increased mortality, post AKI morbidity and high treatment costs. Research on factors related to mortality of AKI patients in intensive care units in Indonesia, especially Cipto Mangungkusumo General Hospital has never been done. This study aims to determine the prevalence of AKI, mortality rate of AKI patients, and the factors associated with increased mortality of AKI patients in intensive care units in ICU Cipto Mangunkusumo General Hospital. Methods: this is a retrospective cohort study of all patients diagnosed with AKI in the intensive care unit at Cipto Mangunkusumo General Hospital, January 2015 - December 2016. An analysis of bivariate relationships with multvariate with STATA Statistics 15.0 between age &amp;gt; 60 years, sepsis, use of ventilator, ventilator duration, dialysis, oligoanuria, and APACHE II scores at admission with mortality. Results: the prevalence of AKI patients in the intensive care unit was 12.25% (675 of 5511 subjects) and 220 subjects (32.59%) of the 675 analyzed subjects died in the intensive care unit. Factors related to increased mortality in multivariate analysis were sepsis (OR 6,174; IK95% 3,116-12,233), oligoanuria (OR 4,173; IK95% 2,104-8,274), use of ventilator (OR 3,085; IK95% 1,348-7,057), (scores APACHE II at admission) 1/2 [OR 1,597; IK95% 1.154-2.209], and the duration of the ventilator (OR 1.062; IK95% 1.012-1.114). Conclusion: the prevalence of AKI patients and their mortality rate in the intensive care unit of Cipto Mangunkusumo General Hospital obtained 12.25% and 32.59%. Sepsis, oligoanuria, ventilators (APACHE II score at admission) 1/2, and ventilator duration are factors that are significantly associated with increased mortality of AKI patients in intensive care units.</dc:description>
	<dc:publisher xml:lang="en-US">The Indonesian Society of Internal Medicine</dc:publisher>
	<dc:date>2020-02-10</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://www.actamedindones.org/index.php/ijim/article/view/1366</dc:identifier>
	<dc:source xml:lang="en-US">Acta Medica Indonesiana; Vol. 51 No. 4 (2019): Acta Medica Indonesiana; 324</dc:source>
	<dc:source>2338-2732</dc:source>
	<dc:source>0125-9326</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://www.actamedindones.org/index.php/ijim/article/view/1366/pdf</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2020 Acta Medica Indonesiana</dc:rights>
</oai_dc:dc>