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The Relationship Between fragmented QRS Complexes (fQRS) and the Severity of Coronary Artery Lesion in Coronary Artery Disease: A Cross-sectional Study

ACTA MEDICA INDONESIANA · Vol. 54 No. 3 (2022)

ISSN
2338-2732, 0125-9326
Published
2022-09-24
Publisher
The Indonesian Society of Internal Medicine
Language
eng

Abstract

Background: The severity of coronary artery lesion is commonly used as a predictor of mortality, major adverse cardiovascular event, and revascularization in coronary artery disease (CAD). Fragmented QRS complex (fQRS) is used as a marker of myocardial ischemia in patients with CAD. The relationship between the two should be studied further. The objective of this study was to determine the relationship between fQRS and the severity of coronary lesion in patients with CAD. Methods: A cross-sectional study was conducted at Cipto Mangunkusumo Hospital Jakarta. Secondary data were taken from 172 patients with CAD who underwent percutaneous coronary intervention (PCI) from January to June 2018 with total sampling. Patients were divided into two groups based on the existence of fQRS. Demographic, clinical, and corangiography characteristics (Gensini score, total vascular lesion, and vascular lesion significance) were studied. Data were analyzed using agreement test and chi-square. Results: fQRS was present in 94 subjects (54.6%). Bivariate analysis showed a significant difference between fQRS with mild-moderate Gensini score as well as mild-severe Gensini score (kappa = 0.721 and 0.820; p<0.001), fQRS with significant CAD (kappa = 0.670; p<0.001), and fQRS with multivessel CAD (kappa = 0.787; p<0.001). Conclusion: There is a significant relationship between fQRS and the degree of severity of coronary lesion in CAD patients.

Keywords

Collaboration network of the authors

40 authors · 259 co-authorship links · showing the 40 most connected

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  • University of Indonesia
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
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Co-authorOrganisationJoint articles
Sally Aman NasutionAffiliation unknown8
Kuntjoro HarimurtiAffiliation unknown6
Lugyanti SukrismanAffiliation unknown5
Simon SalimAffiliation unknown5
Muhammad YaminAffiliation unknown4
Rudi PutrantoAffiliation unknown4
Ikhwan RinaldiAffiliation unknown4
Siti SetiatiAffiliation unknown4
Evy YunihastutiAffiliation unknown4
Hamzah ShatriAffiliation unknown4
Sukamto KoesnoeAffiliation unknown4
Yulianto YuliantoAffiliation unknown3
Idrus AlwiAffiliation unknown3
Arif MansjoerAffiliation unknown3
Em YunirUniversity of Indonesia3
Pringgodigdo NugrohoAffiliation unknown3
Annisa Puspitasari NachrowiAffiliation unknown3
Nurul Inayah RahmaniAffiliation unknown3
Rudy HidayatAffiliation unknown3
Zahra Nuril AnwarAffiliation unknown3
Alvina WidhaniAffiliation unknown2
Anshari Saifuddin HasibuanAffiliation unknown2
Indra WijayaAffiliation unknown2
Dyah PurnamasariAffiliation unknown2
Ni Made HustriniAffiliation unknown2
Dono AntonoAffiliation unknown2
Lusiani RusdiAffiliation unknown2
Cosphiadi IrawanAffiliation unknown2
Noto DwimartutieAffiliation unknown2
Aru W SudoyoAffiliation unknown1
Nata P Hardjo LugitoAffiliation unknown1
Andree KurniawanAffiliation unknown1
Rizki YaruntradhaniAffiliation unknown1
T. Djumhana AtmakusumaAffiliation unknown1
Karmel L TambunanAffiliation unknown1
Shufrie EffendiAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) http://www.actamedindones.org/index.php/ijim/oai, first harvested 8 Nov 2026, last seen 8 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">The Relationship Between fragmented QRS Complexes (fQRS) and the Severity of Coronary Artery Lesion  in Coronary Artery Disease: A Cross-sectional Study</dc:title>
	<dc:creator>Wijaya, Ika Prasetya</dc:creator>
	<dc:creator>Ginanjar, Eka</dc:creator>
	<dc:creator>Rachman, Andhika</dc:creator>
	<dc:creator>Aini, M Hafiz</dc:creator>
	<dc:subject xml:lang="en-US">coronary artery disease</dc:subject>
	<dc:subject xml:lang="en-US">fragmented QRS</dc:subject>
	<dc:subject xml:lang="en-US">Gensini score</dc:subject>
	<dc:description xml:lang="en-US">Background: The severity of coronary artery lesion is commonly used as a predictor of mortality, major adverse cardiovascular event, and revascularization in coronary artery disease (CAD). Fragmented QRS complex (fQRS) is used as a marker of myocardial ischemia in patients with CAD. The relationship between the two should be studied further. The objective of this study was to determine the relationship between fQRS and the severity of coronary lesion in patients with CAD. Methods: A cross-sectional study was conducted at Cipto Mangunkusumo Hospital Jakarta. Secondary data were taken from 172 patients with CAD who underwent percutaneous coronary intervention (PCI) from January to June 2018 with total sampling. Patients were divided into two groups based on the existence of fQRS. Demographic, clinical, and corangiography characteristics (Gensini score, total vascular lesion, and vascular lesion significance) were studied. Data were analyzed using agreement test and chi-square. Results: fQRS was present in 94 subjects (54.6%). Bivariate analysis showed a significant difference between fQRS with mild-moderate Gensini score as well as mild-severe Gensini score (kappa = 0.721 and 0.820; p&amp;lt;0.001), fQRS with significant CAD (kappa = 0.670; p&amp;lt;0.001), and fQRS with multivessel CAD (kappa = 0.787; p&amp;lt;0.001). Conclusion: There is a significant relationship between fQRS and the degree of severity of coronary lesion in CAD patients. </dc:description>
	<dc:publisher xml:lang="en-US">The Indonesian Society of Internal Medicine</dc:publisher>
	<dc:date>2022-09-24</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://www.actamedindones.org/index.php/ijim/article/view/1920</dc:identifier>
	<dc:source xml:lang="en-US">Acta Medica Indonesiana; Vol. 54 No. 3 (2022): Acta Medica Indonesiana; 349</dc:source>
	<dc:source>2338-2732</dc:source>
	<dc:source>0125-9326</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://www.actamedindones.org/index.php/ijim/article/view/1920/pdf</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2022 Eka Ginanjar</dc:rights>
</oai_dc:dc>