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Factors Associated with Hepatitis B and Hepatitis C among Infected Patients in Indonesia and Their Knowledge and Attitude: A Multicenter Observational Study

ACTA MEDICA INDONESIANA · Vol. 56 No. 2 (2024)

ISSN
2338-2732, 0125-9326
Published
2024-07-16
Publisher
The Indonesian Society of Internal Medicine
Language
eng

Abstract

Background: Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infections are global health problems, including in Indonesia. The purpose of this study was to assess the knowledge and attitudes about HBV and HCV infection among infected patients in Indonesia. Methods: This cross-sectional study used a questionnaire survey. The questionnaire was adapted and translated into Indonesian language, and trialed with 27 HBV and 27 HCV patients. The final validated questionnaire was later used in the target population. Patients diagnosed with Hepatitis B or Hepatitis C were included. The patients were enrolled from November 2019 until February 2020 in sixteen multicenter locations. Multivariate analysis with logistic regression was conducted to determine the factors that are associated with the knowledge and attitude among HBV and HCV patients toward their illness. Results: A total of 931 HBV patients and 254 HCV patients were included in this survey. The proportion of infected patients with adequate knowledge of Hepatitis B and Hepatitis C was 72.1% and 53.9%, respectively. Positive attitudes about Hepatitis B and Hepatitis C were 28.5% and 41.3%, respectively. Multivariate analysis revealed that higher education level, higher income level, diagnosis duration of more than 5 years, and receiving of antiviral therapy were independent factors associated with adequate knowledge about Hepatitis B among HBV patients. Among HCV patients, independent factors associated with adequate knowledge about Hepatitis C were being married, higher education level, higher income level, and receiving antiviral therapy. Moreover, older age and receiving of antiviral therapy were independent factors associated with positive attitudes towards Hepatitis B among HBV patients. However, only higher education level was found to be an independent factor associated with positive attitudes towards Hepatitis C among HCV patients. Conclusion: The knowledge and attitude of patients regarding HBV and HCV were quite low among infected patients in Indonesia.

Keywords

Collaboration network of the authors

40 authors · 298 co-authorship links · showing the 40 most connected

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Co-authorOrganisationJoint articles
Rino Alvani GaniAffiliation unknown12
Andri Sanityoso SulaimanAffiliation unknown10
Chyntia Olivia Maurine JasirwanAffiliation unknown8
Kemal Fariz KalistaAffiliation unknown8
Cosmas Rinaldi A LesmanaAffiliation unknown7
Andri SanityosoAffiliation unknown5
Ikhwan RinaldiAffiliation unknown5
Lutfie LutfieAffiliation unknown4
Marcellus SimadibrataAffiliation unknown4
Sally Aman NasutionAffiliation unknown4
Evy YunihastutiAffiliation unknown4
Muhammad Begawan BestariAffiliation unknown4
Muhammad MiftahussururAffiliation unknown3
Titong SugihartonoAffiliation unknown3
Rino A GaniAffiliation unknown3
Siti SetiatiAffiliation unknown3
Hamzah ShatriAffiliation unknown3
Cleopas Martin RumendeAffiliation unknown3
Pringgodigdo NugrohoAffiliation unknown3
Adityo SusiloAffiliation unknown3
Esthika DewiastyAffiliation unknown2

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) http://www.actamedindones.org/index.php/ijim/oai, first harvested 8 Nov 2026, last seen 8 Nov 2026.
Original metadata (oai_dc)
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	<dc:title xml:lang="en-US">Factors Associated with Hepatitis B and Hepatitis C among Infected Patients in Indonesia and Their Knowledge and Attitude: A Multicenter Observational Study</dc:title>
	<dc:creator>Kurniawan, Juferdy</dc:creator>
	<dc:creator>Aprilicia, Gita</dc:creator>
	<dc:creator>Purnomo, Hery Djagat</dc:creator>
	<dc:creator>Permatawedi, Cecilia O</dc:creator>
	<dc:creator>Kholili, Ulfa</dc:creator>
	<dc:creator>Karo-Karo, Tehar</dc:creator>
	<dc:creator>Widita, Haris</dc:creator>
	<dc:creator>Darmayani, Aritantri</dc:creator>
	<dc:creator>Widodo, Arif Nur</dc:creator>
	<dc:creator>Agustanti, Nenny</dc:creator>
	<dc:creator>Miro, Saptino</dc:creator>
	<dc:creator>Suyata, Suyata</dc:creator>
	<dc:creator>Yusuf, Fauzi</dc:creator>
	<dc:creator>Triwikatmani, Catharina</dc:creator>
	<dc:creator>Mustika, Syifa</dc:creator>
	<dc:creator>Bachtiar, Rini R</dc:creator>
	<dc:creator>Gosal, Fandy</dc:creator>
	<dc:creator>Mariadi, I Ketut</dc:creator>
	<dc:creator>Hasan, Irsan</dc:creator>
	<dc:subject xml:lang="en-US">Knowledge</dc:subject>
	<dc:subject xml:lang="en-US">Attitude</dc:subject>
	<dc:subject xml:lang="en-US">Hepatitis B</dc:subject>
	<dc:subject xml:lang="en-US">Hepatitis C</dc:subject>
	<dc:subject xml:lang="en-US">internal medicine</dc:subject>
	<dc:subject xml:lang="en-US">hepatology</dc:subject>
	<dc:subject xml:lang="en-US">public health</dc:subject>
	<dc:description xml:lang="en-US">Background: Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infections are global health problems, including in Indonesia. The purpose of this study was to assess the knowledge and attitudes about HBV and HCV infection among infected patients in Indonesia. Methods: This cross-sectional study used a questionnaire survey. The questionnaire was adapted and translated into Indonesian language, and trialed with 27 HBV and 27 HCV patients. The final validated questionnaire was later used in the target population. Patients diagnosed with Hepatitis B or Hepatitis C were included. The patients were enrolled from November 2019 until February 2020 in sixteen multicenter locations. Multivariate analysis with logistic regression was conducted to determine the factors that are associated with the knowledge and attitude among HBV and HCV patients toward their illness. Results: A total of 931 HBV patients and 254 HCV patients were included in this survey. The proportion of infected patients with adequate knowledge of Hepatitis B and Hepatitis C was 72.1% and 53.9%, respectively. Positive attitudes about Hepatitis B and Hepatitis C were 28.5% and 41.3%, respectively. Multivariate analysis revealed that higher education level, higher income level, diagnosis duration of more than 5 years, and receiving of antiviral therapy were independent factors associated with adequate knowledge about Hepatitis B among HBV patients. Among HCV patients, independent factors associated with adequate knowledge about Hepatitis C were being married, higher education level, higher income level, and receiving antiviral therapy. Moreover, older age and receiving of antiviral therapy were independent factors associated with positive attitudes towards Hepatitis B among HBV patients. However, only higher education level was found to be an independent factor associated with positive attitudes towards Hepatitis C among HCV patients. Conclusion: The knowledge and attitude of patients regarding HBV and HCV were quite low among infected patients in Indonesia.</dc:description>
	<dc:publisher xml:lang="en-US">The Indonesian Society of Internal Medicine</dc:publisher>
	<dc:date>2024-07-16</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://www.actamedindones.org/index.php/ijim/article/view/2448</dc:identifier>
	<dc:source xml:lang="en-US">Acta Medica Indonesiana; Vol. 56 No. 2 (2024): Acta Medica Indonesiana; 155</dc:source>
	<dc:source>2338-2732</dc:source>
	<dc:source>0125-9326</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://www.actamedindones.org/index.php/ijim/article/view/2448/pdf</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2024 Juferdy Kurniawan</dc:rights>
</oai_dc:dc>