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The Effect of Exercise Training as Adjuvant Treatment on Functional Capacity in Congenital Heart Disease with Negative Vaso Reactivity Test Pulmonary Hypertension Patient at Saiful Anwar Hospital Malang

Heart Science Journal · Vol. 4 No. 3 (2023) · pp. 12–16

DOI
10.21776/ub.hsj.2023.004.03.3
ISSN
2721-9984, 2721-9976
Published
2023-07-01
Publisher
Universitas Brawijaya
Language
en

Abstract

BackgroundPulmonary hypertension associated with congenital heart disease (CHD) is an important subgroup that accounts for approximately 11% of all patients with PAH. Physical limitations are one of the main symptoms of hemodynamic changes in patients with PH. Objective This study aimed to evaluate the effect of physical exercise therapy for 12 weeks as an additional therapy with PDE-5 inhibitors on the functional capacity of patients with Congenital Heart Disease accompanied by Pulmonary Artery Hypertension (CHD – PH). MethodThis research was an analytic experimental study with a prospective cohort research method. This study used data sources obtained from medical records to adjust subjects based on inclusion and exclusion criteria, initial cardiac training test examination data was carried out at IPJT in patients selected as subjects. The patient's clinical outcomes were followed in the next 12 weeks. ResultThis research was conducted on 16 samples divided into two groups, namely the control and study groups. The evaluation after 12 weeks found that there was an increase in mileage as measured through the 6MWT submaximal test and a better duration of physical activity in the study group tested through the Endurance Shuttle Walk Test (ESWT). This is consistent with the effect of physical exercise, which suppresses systemic inflammation and causes vasodilation, thereby increasing oxygen delivery to the tissues. This causes more optimal aerobic metabolism and reduces lactate production. So that the patient did not quickly feel tired during activities. However, there was no significant increase in the Incremental Shuttle Walk Test. This could be due to the relatively short training duration of 12 weeks. Conclusion A positive correlation exists between physical exercise and increased functional capacity of patients with CHD who were evaluated using 6MWT and ESWT.

Keywords

Collaboration network of the authors

40 authors · 292 co-authorship links · showing the 40 most connected

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  • University of Brawijaya
  • Affiliation unknown
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Co-authorOrganisationJoint articles
Mohammad Saifur RohmanAffiliation unknown41
Indra PrasetyaAffiliation unknown31
Anna Fuji RahimahAffiliation unknown28
Ardian RizalAffiliation unknown22
Novi KurnianingsihAffiliation unknown21
Budi SatrijoAffiliation unknown21
Djanggan SargowoAffiliation unknown16
Sasmojo WiditoAffiliation unknown15
Valerinna YogibuanaAffiliation unknown10
Yoga WaranugrahaAffiliation unknown5
Muhammad Rizki FadlanAffiliation unknown5
Muhammad FirdausAffiliation unknown5
Wella KarolinaAffiliation unknown5
Lukitasari Ayu GaluhAffiliation unknown4
Ayu Asri Devi AdityawatiAffiliation unknown4
Zainal FathurohimAffiliation unknown4
Teguh AryanugrahaAffiliation unknown4
Dadang HendrawanAffiliation unknown3
Krishna Ari NugrahaAffiliation unknown3
Seprian WidasmaraAffiliation unknown3
Arif WicaksonoAffiliation unknown3
Evit RuspionoAffiliation unknown3
Dion SetiawanAffiliation unknown3
Valerinna Yogibuana Swastika PutriAffiliation unknown3
Lutfi Hafiz ZunardiAffiliation unknown3
Akhmad Isna NurudinullohAffiliation unknown3
Putri Annisa KamilaUniversity of Brawijaya3
Ratna PancasariAffiliation unknown3
Adhika Prastya WikanandaAffiliation unknown3
Imam Mi'raj SuprayogaAffiliation unknown3
Yoseph Budi UtomoAffiliation unknown2
Taufieq Ridlo MakhmudAffiliation unknown2
Faris Wahyu NugrohoAffiliation unknown2
Tonny AdriyantoAffiliation unknown2
Olivia HandayaniAffiliation unknown2

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://heartscience.ub.ac.id/index.php/heartscience/oai, first harvested 8 Nov 2026, last seen 8 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">The Effect of Exercise Training as Adjuvant Treatment on Functional Capacity in Congenital Heart Disease with Negative Vaso Reactivity Test Pulmonary Hypertension Patient at Saiful Anwar Hospital Malang</dc:title>
	<dc:creator xml:lang="en">Pratiwi, Irma Kamelia</dc:creator>
	<dc:creator xml:lang="en">Martini, Heny</dc:creator>
	<dc:creator xml:lang="en">Tjahjono, Cholid Tri</dc:creator>
	<dc:creator xml:lang="en">Anjarwani, Setyasih</dc:creator>
	<dc:creator xml:lang="en">Handari, Saskia Dyah</dc:creator>
	<dc:subject xml:lang="en">Pulmonary arterial hypertension</dc:subject>
	<dc:subject xml:lang="en">congenital heart disease</dc:subject>
	<dc:subject xml:lang="en">exercise training</dc:subject>
	<dc:subject xml:lang="en">functional capacity</dc:subject>
	<dc:description xml:lang="en">BackgroundPulmonary hypertension associated with congenital heart disease (CHD) is an important subgroup that accounts for approximately 11% of all patients with PAH. Physical limitations are one of the main symptoms of hemodynamic changes in patients with PH. Objective This study aimed to evaluate the effect of physical exercise therapy for 12 weeks as an additional therapy with PDE-5 inhibitors on the functional capacity of patients with Congenital Heart Disease accompanied by Pulmonary Artery Hypertension (CHD – PH). MethodThis research was an analytic experimental study with a prospective cohort research method. This study used data sources obtained from medical records to adjust subjects based on inclusion and exclusion criteria, initial cardiac training test examination data was carried out at IPJT in patients selected as subjects. The patient's clinical outcomes were followed in the next 12 weeks. ResultThis research was conducted on 16 samples divided into two groups, namely the control and study groups. The evaluation after 12 weeks found that there was an increase in mileage as measured through the 6MWT submaximal test and a better duration of physical activity in the study group tested through the Endurance Shuttle Walk Test (ESWT). This is consistent with the effect of physical exercise, which suppresses systemic inflammation and causes vasodilation, thereby increasing oxygen delivery to the tissues. This causes more optimal aerobic metabolism and reduces lactate production. So that the patient did not quickly feel tired during activities. However, there was no significant increase in the Incremental Shuttle Walk Test. This could be due to the relatively short training duration of 12 weeks. Conclusion A positive correlation exists between physical exercise and increased functional capacity of patients with CHD who were evaluated using 6MWT and ESWT.</dc:description>
	<dc:publisher xml:lang="en">Universitas Brawijaya</dc:publisher>
	<dc:date>2023-07-01</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://heartscience.ub.ac.id/index.php/heartscience/article/view/10836</dc:identifier>
	<dc:identifier>10.21776/ub.hsj.2023.004.03.3</dc:identifier>
	<dc:source xml:lang="en">Heart Science Journal; Vol. 4 No. 3 (2023): The Essensial Role of the Metabolic Syndrome in the Development of Cardiovascular Disease; 12-16</dc:source>
	<dc:source>2721-9984</dc:source>
	<dc:source>2721-9976</dc:source>
	<dc:source>10.21776/ub.hsj.2023.004.03</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://heartscience.ub.ac.id/index.php/heartscience/article/view/10836/348</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2023 Irma Kamelia Pratiwi, Heny Martini, cholid Tri Tjahjono, Setyasih Anjarwani, Saskia Dyah Handari</dc:rights>
</oai_dc:dc>