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Neutrophil-Lymphocyte Ratio value as a predictor of Troponin Elevation in patients with Non-ST Segment Elevation Acute Coronary Syndrome

Heart Science Journal · Vol. 5 No. 1 (2024) · pp. 4–9

DOI
10.21776/ub/hsj.2024.005.01.2
ISSN
2721-9984, 2721-9976
Published
2024-01-31
Publisher
Universitas Brawijaya
Language
en

Abstract

Acute coronary syndrome (ACS) is a prominent contributor to mortality and morbidity on a global scale, consistently ranking within the top five primary causes. Inflammation is one of the many elements that have a role in the pathophysiology of the development and destabilization of plaque atherosclerosis in ACS. Troponin is a component of a biomarker that signals damage to the heart muscle in ACS patients; however, at the present time, not all medical facilities are able to perform troponin testing. An acute myocardial infarction begins with an initial inflammatory process that generates proinflammatory cytokines at the cellular level. This can be evaluated by the NLR through peripheral blood tests. The NLR as an indication of systemic inflammation has been demonstrated to be associated with poor clinical outcomes, an increased risk of complications, and mortality in ACS patients. In addition, several studies showed that the NLR has prognostic value in patients with ACS. The NLR is a mix of inflammatory markers, which can be a predictor of increased troponin in cases of non-ST segment elevation acute coronary syndrome (NSTEACS) in an emergency room.

Keywords

Collaboration network of the authors

40 authors · 295 co-authorship links · showing the 40 most connected

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  • University of Brawijaya
  • Affiliation unknown
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  • Same organisation
  • Affiliation unknown
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Co-authorOrganisationJoint articles
Mohammad Saifur RohmanAffiliation unknown52
Ardian RizalAffiliation unknown34
Budi SatrijoAffiliation unknown29
Cholid Tri TjahjonoAffiliation unknown22
Heny MartiniAffiliation unknown21
Novi KurnianingsihAffiliation unknown19
Djanggan SargowoAffiliation unknown18
Wella KarolinaAffiliation unknown11
Sasmojo WiditoAffiliation unknown11
Valerinna YogibuanaAffiliation unknown10
Nikhen NoverikeAffiliation unknown5
Imelda KrisnasariAffiliation unknown5
Muhammad Rizki FadlanAffiliation unknown5
Putri Annisa KamilaUniversity of Brawijaya4
Ayu Asri Devi AdityawatiAffiliation unknown4
Tri AstiawatiAffiliation unknown4
Valerinna Yogibuana Swastika PutriAffiliation unknown4
Teguh AryanugrahaAffiliation unknown4
Hayla Iqda MillisaniAffiliation unknown3
Lukitasari Ayu GaluhAffiliation unknown3
Danti Utami SetyowatiAffiliation unknown3
Yoseph Budi UtomoAffiliation unknown3
Yoga WaranugrahaAffiliation unknown3
Anita Surya SantosoAffiliation unknown3
Krishna Ari NugrahaAffiliation unknown3
Seprian WidasmaraAffiliation unknown3
Diah Ivana SariAffiliation unknown3
Fahmy RusnantaAffiliation unknown3
Dea Arie KurniawanAffiliation unknown3
Oktafin Srywati PamunaAffiliation unknown3
Saskia Dyah HandariAffiliation unknown3
Veny KurniawatiAffiliation unknown2
Olivia HandayaniAffiliation unknown2
Cholid Tri TjahjonoAffiliation unknown2
Ratna PancasariAffiliation unknown2
Liemena Harold AdrianAffiliation unknown2

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://heartscience.ub.ac.id/index.php/heartscience/oai, first harvested 8 Nov 2026, last seen 8 Nov 2026.
Original metadata (oai_dc)
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Neutrophil-Lymphocyte Ratio value as a predictor of Troponin Elevation in patients with Non-ST Segment Elevation Acute Coronary Syndrome</dc:title>
	<dc:creator xml:lang="en">zunardi, Lutfi hafiz</dc:creator>
	<dc:creator xml:lang="en">Anjarwani, Setyasih</dc:creator>
	<dc:creator xml:lang="en">Prasetya, Indra</dc:creator>
	<dc:creator xml:lang="en">Rahimah, Anna Fuji</dc:creator>
	<dc:subject xml:lang="en">Acute Coronary Syndrome</dc:subject>
	<dc:subject xml:lang="en">Cardiac Enzyme</dc:subject>
	<dc:subject xml:lang="en">Neurotrophil-Lymphocyte Ratio</dc:subject>
	<dc:subject xml:lang="en">Non-ST Elevation Myocardial Infarction</dc:subject>
	<dc:subject xml:lang="en">Primary Percutaneous Coronary Intervention</dc:subject>
	<dc:subject xml:lang="en">Troponin</dc:subject>
	<dc:description xml:lang="en">Acute coronary syndrome (ACS) is a prominent contributor to mortality and morbidity on a global scale, consistently ranking within the top five primary causes. Inflammation is one of the many elements that have a role in the pathophysiology of the development and destabilization of plaque atherosclerosis in ACS. Troponin is a component of a biomarker that signals damage to the heart muscle in ACS patients; however, at the present time, not all medical facilities are able to perform troponin testing. An acute myocardial infarction begins with an initial inflammatory process that generates proinflammatory cytokines at the cellular level. This can be evaluated by the NLR through peripheral blood tests. The NLR as an indication of systemic inflammation has been demonstrated to be associated with poor clinical outcomes, an increased risk of complications, and mortality in ACS patients. In addition, several studies showed that the NLR has prognostic value in patients with ACS. The NLR is a mix of inflammatory markers, which can be a predictor of increased troponin in cases of non-ST segment elevation acute coronary syndrome (NSTEACS) in an emergency room.</dc:description>
	<dc:publisher xml:lang="en">Universitas Brawijaya</dc:publisher>
	<dc:date>2024-01-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://heartscience.ub.ac.id/index.php/heartscience/article/view/13843</dc:identifier>
	<dc:identifier>10.21776/ub/hsj.2024.005.01.2</dc:identifier>
	<dc:source xml:lang="en">Heart Science Journal; Vol. 5 No. 1 (2024): Inflammation and Cardiovascular Disease; 4-9</dc:source>
	<dc:source>2721-9984</dc:source>
	<dc:source>2721-9976</dc:source>
	<dc:source>10.21776/ub.hsj.2024.005.01</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://heartscience.ub.ac.id/index.php/heartscience/article/view/13843/389</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2024 Lutfi hafiz zunardi, Setyasih Anjarwani, Sasmojo Widito, Valerinna Yogibuana Swastika Putri</dc:rights>
</oai_dc:dc>