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Causal Modeling Between Factors on Quality of Life in Cancer Patients Using S3C-Latent Algorithm

Journal of Information Systems Engineering and Business Intelligence · Vol. 7 No. 1 (2021) · pp. 74–83

DOI
10.20473/jisebi.7.1.74-83
ISSN
2443-2555, 2598-6333
Published
2021-04-27
Publisher
Universitas Airlangga
Language
eng

Abstract

Background: Cancer patients can experience both physical and non-physical problems such as psychosocial, spiritual, and emotional problems, which impact the quality of life. Previous studies on quality of life mostly have employed multivariate analyses. To our knowledge, no studies have focused yet on the underlying causal relationship between factors representing the quality of life of cancer patients, which is very important when attempting to improve the quality of life. Objective: The study aims to model the causal relationships between the factors that represent cancer and quality of life.Methods: This study uses the S3C-Latent method to estimate the causal model relationships between the factors. The S3C-Latent method combines Structural Equation Model (SEM), a multi objective optimization method, and the stability selection approach, to estimate a stable and parsimonious causal model.Results: There are nine causal relations that have been found, i.e., from physical to global health with a reliability score of 0.73, to performance status with a reliability score of 1, from emotional to global health with a reliability score of 0.71, to performance status with a reliability score of 0.82, from nausea, loss of appetite, dyspnea, insomnia, loss of appetite and from constipation to performance status with reliability scores of 0.76; 1; 0.61; 0.76; 0.72; 0.70, respectively. Moreover, this study found that 15 associations (strong relation where the causal direction cannot be determined from the data alone) between factors with reliability scores range from 0.65 to 1.Conclusion: The estimated model is consistent with the results shown in previous studies. The model is expected to provide evidence-based recommendation for health care providers in designing strategies to increase cancer patients' life quality. For future research, we suggest studies to include more variables in the model to capture a broader view to the problem.

Collaboration network of the authors

17 authors · 32 co-authorship links · 12 across different organisations

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

  • Institut Teknologi Telkom Purwokerto
  • Islamic University of Indonesia
  • Universitas Gadjah Mada
  • Hasanuddin University
  • University of Nigeria
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Nur ChayatiAffiliation unknown2
Ismail SetyopranotoAffiliation unknown2
Yuan Sa'adatiIslamic University of Indonesia2
Rizki Surtiyan SuryaIslamic University of Indonesia2
Siti KhomsahInstitut Teknologi Telkom Purwokerto1
Mohammad Teddy SyamkallaInstitut Teknologi Telkom Purwokerto1
Andina SetyawatiHasanuddin University1
Mae Sri Hartati WahyuningsihUniversitas Gadjah Mada1
Dwi Aris Agung NugrahaningsihUniversitas Gadjah Mada1
Sam Chidi IbenemeUniversity of Nigeria1
Nyoman Sri SubawaAffiliation unknown1
Marselus YansenAffiliation unknown1
Anak Agung Made WirajayaAffiliation unknown1
AKICHIKA MIKAMIAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://e-journal.unair.ac.id/JISEBI/oai, first harvested 29 Oct 2026, last seen 8 Nov 2026.
Original metadata (oai_dc)
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	<dc:title xml:lang="en-US">Causal Modeling Between Factors on Quality of Life in Cancer Patients Using S3C-Latent Algorithm</dc:title>
	<dc:creator>Nur, Yohani Setiya Rafika</dc:creator>
	<dc:creator>Rahmadi, Ridho</dc:creator>
	<dc:creator>Effendy, Christantie</dc:creator>
	<dc:description xml:lang="en-US">Background: Cancer patients can experience both physical and non-physical problems such as psychosocial, spiritual, and emotional problems, which impact the quality of life. Previous studies on quality of life mostly have employed multivariate analyses. To our knowledge, no studies have focused yet on the underlying causal relationship between factors representing the quality of life of cancer patients, which is very important when attempting to improve the quality of life.  Objective: The study aims to model the causal relationships between the factors that represent cancer and quality of life.Methods: This study uses the S3C-Latent method to estimate the causal model relationships between the factors. The S3C-Latent method combines Structural Equation Model (SEM), a multi objective optimization method, and the stability selection approach, to estimate a stable and parsimonious causal model.Results: There are nine causal relations that have been found, i.e., from physical to global health with a reliability score of 0.73, to performance status with a reliability score of 1, from emotional to global health with a reliability score of 0.71, to performance status with a reliability score of 0.82, from nausea, loss of appetite, dyspnea, insomnia, loss of appetite and from constipation to performance status with reliability scores of 0.76; 1; 0.61; 0.76; 0.72; 0.70, respectively. Moreover, this study found that 15 associations (strong relation where the causal direction cannot be determined from the data alone) between factors with reliability scores range from 0.65 to 1.Conclusion: The estimated model is consistent with the results shown in previous studies. The model is expected to provide evidence-based recommendation for health care providers in designing strategies to increase cancer patients' life quality. For future research, we suggest studies to include more variables in the model to capture a broader view to the problem.</dc:description>
	<dc:publisher xml:lang="en-US">Universitas Airlangga</dc:publisher>
	<dc:date>2021-04-27</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://e-journal.unair.ac.id/JISEBI/article/view/25685</dc:identifier>
	<dc:identifier>10.20473/jisebi.7.1.74-83</dc:identifier>
	<dc:source xml:lang="en-US">Journal of Information Systems Engineering and Business Intelligence; Vol. 7 No. 1 (2021): April; 74-83</dc:source>
	<dc:source>2443-2555</dc:source>
	<dc:source>2598-6333</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://e-journal.unair.ac.id/JISEBI/article/view/25685/13995</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2021 The Authors. Published by Universitas Airlangga.</dc:rights>
</oai_dc:dc>