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Flavonoid Compounds from the Herb of Krokot (Lygodium microphyllum) and their antioxidant activity against DPPH

Journal of Mathematical and Fundamental Sciences · Vol. 50 No. 2 (2018) · pp. 192–202

DOI
10.5614/j.math.fund.sci.2018.50.2.7
ISSN
2338-5510, 2337-5760
Published
2018-08-31
Publisher
Directorate for Research and Innovation (DRI) ITB
Language
eng

Abstract

Six flavonoid compounds, kaempferol (1), quercetin (2), acacetin (3), quercetin-3-O-β-D-glucopyranoside (4), kaempferol-3-O-β-D-glucopyranoside (5), and isorhamnetin-3-O-β-D-glucopyranoside (6), were isolated from the methanol extract of the Lygodium microphyllum herb. The chemical structures of compounds 1-6 were identified on the basis of spectroscopic evidence and comparison with previously reported spectral data. Compounds 1-6 were isolated for first time from this plant. Their antioxidant activity against DPPH (2,2-Diphenyl-1-picrylhydrazyl) was evaluated. Among the compounds, quercetin (2) showed high antioxidant activity with IC50 values of 6.94 ± 0.03 μg/mL.

Keywords

Collaboration network of the authors

40 authors · 289 co-authorship links · showing the 40 most connected

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  • University of Malaya
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Desi HarnetiAffiliation unknown34
Nurlelasari NurlelasariAffiliation unknown34
Tri MayantiAffiliation unknown28
Rani MaharaniAffiliation unknown28
Sofa FajriahAffiliation unknown23
Al Arofatus NainiAffiliation unknown20
Ace Tatang HidayatAffiliation unknown18
Darwati DarwatiAffiliation unknown13
Tati HerlinaAffiliation unknown10
Mohamad Nurul AzmiAffiliation unknown10
Wahyu SafriansyahAffiliation unknown9
Dewa Gede KatjaAffiliation unknown8
Fajar Fauzi AbdullahAffiliation unknown8
Erina HilmayantiAffiliation unknown8
Khalijah AwangUniversity of Malaya6
Risyandi AnwarAffiliation unknown6
Harizon HarizonAffiliation unknown5
Dudi RunadiAffiliation unknown4
Purnama PurnamaAffiliation unknown4
Ricson Pemimpin HutagaolAffiliation unknown4
Muhammad HanafiAffiliation unknown4
Mohamad Azlan NafiahAffiliation unknown4
Ferry Ferdiansyah SofianAffiliation unknown4
Desi Harneti Putri HuspaAffiliation unknown4
Ronny LesmanaAffiliation unknown3
Sandra Amalia RiyadiAffiliation unknown3
Agus SafariAffiliation unknown3
Sari PurbayaAffiliation unknown3
Aprilia Permata SariAffiliation unknown3
Rurini RetnowatiAffiliation unknown3
Supriatno SalamAffiliation unknown3
Islamudin AhmadAffiliation unknown2
Susianti SusiantiAffiliation unknown2
Raihan Fathurrahman HasbillaAffiliation unknown2

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journals.itb.ac.id/index.php/jmfs/oai, first harvested 9 Nov 2026, last seen 9 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">Flavonoid Compounds from the Herb of Krokot (Lygodium microphyllum) and their antioxidant activity against DPPH</dc:title>
	<dc:creator>Kuncoro, Hadi</dc:creator>
	<dc:creator>Farabi, Kindi</dc:creator>
	<dc:creator>Rijai, Laode</dc:creator>
	<dc:creator>Julaeha, Euis</dc:creator>
	<dc:creator>Supratman, Unang</dc:creator>
	<dc:creator>Shiono, Yoshihito</dc:creator>
	<dc:subject xml:lang="en-US">Antioxidant</dc:subject>
	<dc:subject xml:lang="en-US">DPPH</dc:subject>
	<dc:subject xml:lang="en-US">flavonoids</dc:subject>
	<dc:subject xml:lang="en-US">Lygodium microphyllum</dc:subject>
	<dc:subject xml:lang="en-US">Lygodiaceae</dc:subject>
	<dc:description xml:lang="en-US">Six flavonoid compounds, kaempferol (1), quercetin (2), acacetin (3), quercetin-3-O-β-D-glucopyranoside (4), kaempferol-3-O-β-D-glucopyranoside (5), and isorhamnetin-3-O-β-D-glucopyranoside (6), were isolated from the methanol extract of the Lygodium microphyllum herb. The chemical structures of compounds 1-6 were identified on the basis of spectroscopic evidence and comparison with previously reported spectral data. Compounds 1-6 were isolated for first time from this plant. Their antioxidant activity against DPPH (2,2-Diphenyl-1-picrylhydrazyl) was evaluated. Among the compounds, quercetin (2) showed high antioxidant activity with IC50 values of 6.94 ± 0.03 μg/mL.</dc:description>
	<dc:publisher xml:lang="en-US">Directorate for Research and Innovation (DRI) ITB</dc:publisher>
	<dc:date>2018-08-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journals.itb.ac.id/index.php/jmfs/article/view/5598</dc:identifier>
	<dc:identifier>10.5614/j.math.fund.sci.2018.50.2.7</dc:identifier>
	<dc:source xml:lang="en-US">Journal of Mathematical and Fundamental Sciences; Vol. 50 No. 2 (2018); 192-202</dc:source>
	<dc:source>2338-5510</dc:source>
	<dc:source>2337-5760</dc:source>
	<dc:source>10.5614/j.math.fund.sci.2018.50.2</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journals.itb.ac.id/index.php/jmfs/article/view/5598/3058</dc:relation>
</oai_dc:dc>