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Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha)

VALENSI · Vol. ume No. 2 (2018) · pp. 75–78

DOI
10.15408/jkv.v4i2.7304
ISSN
2548-3013, 2460-6065
Published
2018-11-30
Publisher
Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University
Language
eng

Abstract

Two flavonoid compounds, kaempferol (1) and quercetin (2) have been isolated from the leaves of Rasamala (Altingia excelsa Nornha). The chemical structure of compounds 1 and 2 were identified by spectroscopic evidences including, UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously reported spectral data.These compounds were isolated from this plant for the first time. Compounds 1 and 2 were evaluated for their antiproliferative activity against SP-C1 cancer tongue cells and showed IC50 values of 2.50 and 2.31 mM, respectively.

Keywords

Collaboration network of the authors

40 authors · 272 co-authorship links · showing the 40 most connected

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  • University of Malaya
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
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Co-authorOrganisationJoint articles
Kindi FarabiAffiliation unknown21
Desi HarnetiAffiliation unknown19
Nurlelasari NurlelasariAffiliation unknown18
Tri MayantiAffiliation unknown16
Yoshihito ShionoAffiliation unknown13
Rani MaharaniAffiliation unknown13
Al Arofatus NainiAffiliation unknown13
Sofa FajriahAffiliation unknown12
Ace Tatang HidayatAffiliation unknown10
Tati HerlinaAffiliation unknown8
Darwati DarwatiAffiliation unknown7
Wahyu SafriansyahAffiliation unknown5
Mohamad Nurul AzmiAffiliation unknown5
Fajar Fauzi AbdullahAffiliation unknown5
Hadi KuncoroAffiliation unknown4
Euis JulaehaAffiliation unknown4
Dewa Gede KatjaAffiliation unknown4
Erina HilmayantiAffiliation unknown4
Wardiah WardiahAffiliation unknown3
Ronny LesmanaAffiliation unknown3
Khalijah AwangUniversity of Malaya3
Harizon HarizonAffiliation unknown3
Sandra Amalia RiyadiAffiliation unknown3
Sartari Entin YuletnawatiAffiliation unknown2
Laode RijaiAffiliation unknown2
Dudi RunadiAffiliation unknown2
Purnama PurnamaAffiliation unknown2
Susianti SusiantiAffiliation unknown2
Raihan Fathurrahman HasbillaAffiliation unknown2
Agus SafariAffiliation unknown2
Ricson Pemimpin HutagaolAffiliation unknown2
Muhammad HanafiAffiliation unknown2
Sari PurbayaAffiliation unknown2
Aprilia Permata SariAffiliation unknown2
Mohamad Azlan NafiahAffiliation unknown2
Ferry Ferdiansyah SofianAffiliation unknown2

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) http://journal.uinjkt.ac.id/index.php/valensi/oai, first harvested 10 Nov 2026, last seen 10 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en">Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala  (Altingia excelsa Nornha)</dc:title>
	<dc:creator xml:lang="en">Anwar, Risyandi</dc:creator>
	<dc:creator xml:lang="en">Setiawan, Arlette</dc:creator>
	<dc:creator xml:lang="en">Supriatno, Supriatno</dc:creator>
	<dc:creator xml:lang="en">Supratman, Unang</dc:creator>
	<dc:subject xml:lang="en">Altingia excelsa</dc:subject>
	<dc:subject xml:lang="en">SP-C1 cancer tongue cells</dc:subject>
	<dc:subject xml:lang="en">kaempferol</dc:subject>
	<dc:subject xml:lang="en">quercetin</dc:subject>
	<dc:description xml:lang="en">Two flavonoid compounds, kaempferol (1) and quercetin (2) have been isolated from the leaves of Rasamala (Altingia excelsa Nornha). The chemical structure of compounds 1 and 2 were identified by spectroscopic evidences including, UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously reported spectral data.These compounds were isolated from this plant for the first time. Compounds 1 and 2 were evaluated for their antiproliferative activity against SP-C1 cancer tongue cells and showed IC50 values of 2.50 and 2.31 mM, respectively.  </dc:description>
	<dc:publisher xml:lang="en">Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University</dc:publisher>
	<dc:date>2018-11-30</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.uinjkt.ac.id/index.php/valensi/article/view/7304</dc:identifier>
	<dc:identifier>10.15408/jkv.v4i2.7304</dc:identifier>
	<dc:source xml:lang="en">Jurnal Kimia Valensi; Jurnal Kimia VALENSI Volume 4, No. 2, November 2018; 75-78</dc:source>
	<dc:source>2548-3013</dc:source>
	<dc:source>2460-6065</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journal.uinjkt.ac.id/index.php/valensi/article/view/7304/pdf</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2019 Risyandi Anwar, Arlette Setiawan, Supriatno Supriatno, Unang Supratman</dc:rights>
</oai_dc:dc>