Open access Journal SINTA 1
Synthesis of 3-(4-Hydroxy-3-Methoxyphenyl)-1-(2-Hydroxyphenyl)-Propenone as a Colorimetric Chemosensor for Hydrogen Phosphate Anions
VALENSI · Vol. ume No. 1 (2026) · pp. 144–155
- ISSN
- 2548-3013, 2460-6065
- Published
- 2026-06-06
- Publisher
- Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University
- Language
- eng
Abstract
Hydrogen phosphate is an important anion in environmental and biological systems; however, its excessive presence in water can contribute to eutrophication and water quality degradation. The synthesis and application of 3-(4-hydroxy-3-methoxyphenyl)-1-(2-hydroxyphenyl)-propenone (HMPP) as a colorimetric chemosensor for hydrogen phosphate (HPO₄²⁻) anions have been investigated. HMPP was synthesized via Claisen–Schmidt condensation of vanillin and 2-hydroxyacetophenone, obtained in 34% yield of the target compound. The colorimetric response of HMPP was evaluated toward various anions, including F⁻, Cl⁻, Br⁻, CN⁻, HPO₄²⁻, and CO₃²⁻. The results showed that HMPP exhibited a distinct response toward HPO₄²⁻; however, the presence of other anions caused varying degrees of interference, with CO₃²⁻ showing minimal effect, while Cl⁻, CN⁻, and Br⁻ reduced the response to a greater extent. This behavior is attributed to hydrogen-bonding interactions between HMPP and HPO₄²⁻, which enhance intramolecular charge transfer (ICT). The applicability of HMPP was further evaluated in spiked tap water samples, demonstrating satisfactory recovery in the range of 105.47–107.50%, indicating acceptable accuracy and reliability. Therefore, HMPP demonstrates potential as a colorimetric chemosensor for hydrogen phosphate anions in water samples.
Keywords
Collaboration network of the authors
40 authors · 185 co-authorship links · 8 across different organisations · showing the 40 most connected
Hover or tap a name to highlight its co-authors. Double-click to open the author's page.
- Hasanuddin University
- Universitas Islam Negeri Sjech M. Djamil Djambek Bukittinggi
- Politeknik Negeri Ujung Pandang
- Universitas Islam Negeri Sulthan Thaha Saifuddin Jambi
- Cenderawasih University
- Affiliation unknown
- Different organisations
- Same organisation
- Affiliation unknown
- Thicker line = more joint articles · bigger circle = more articles
Show as table
| Co-author | Organisation | Joint articles |
|---|---|---|
| Muhammad Zakir | Hasanuddin University | 6 |
| Nursiah La Nafie | Affiliation unknown | 4 |
| St Fauziah | Affiliation unknown | 4 |
| Nunuk Hariani Soekamto | Affiliation unknown | 4 |
| Hasnah Natsir | Affiliation unknown | 4 |
| La Kolo | Affiliation unknown | 3 |
| Djabal Nur Basir | Hasanuddin University | 3 |
| Alfian Noor | Hasanuddin University | 2 |
| Firdaus Firdaus | Affiliation unknown | 2 |
| Abdul Wahid Wahab | Affiliation unknown | 2 |
| Syahruddin Kasim | Affiliation unknown | 2 |
| Siti Khairunnur | Affiliation unknown | 2 |
| Maming | Affiliation unknown | 2 |
| Ihsanul Arief | Affiliation unknown | 2 |
| Andi Muhammad Anshar | Hasanuddin University | 2 |
| Wiji Utami | Universitas Islam Negeri Sulthan Thaha Saifuddin Jambi | 2 |
| Yusafir Hala | Affiliation unknown | 2 |
| Vilkhiyam Vilkhiyam | Universitas Islam Negeri Sjech M. Djamil Djambek Bukittinggi | 1 |
| Yuliana Yuliana | Cenderawasih University | 1 |
| Ritayani Ritayani | Universitas Islam Negeri Sjech M. Djamil Djambek Bukittinggi | 1 |
| Zulfani Sesmiarni | Universitas Islam Negeri Sjech M. Djamil Djambek Bukittinggi | 1 |
| Saefuddin . | Affiliation unknown | 1 |
| Tjodi Harlim | Affiliation unknown | 1 |
| Ahmad Zaini | Affiliation unknown | 1 |
| Zarlina | Affiliation unknown | 1 |
| M Sirih | Affiliation unknown | 1 |
Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.