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Hiperglikemia dan Status Inflamasi pada Pasien Sindroma Koroner Akut

MEDULA (JURNAL ILMIAH FAKULTAS KEDOKTERAN UNIVERSITAS HALU OLEO) · Vol. 6 No. 2 (2019)

DOI
10.46496/medula.v6i2.6724
ISSN
2443-0218, 2339-1006
Published
2019-05-13
Publisher
Halu Oleo University
Language
eng

Abstract

ABSTRACTBackground: Hyperglycaemia in patients with acute coronary syndromes (ACS) is associated with increased cardiovas­cular (CV) risk. Hyperglycaemia in patients with ACS may be associated with increased systemic inflammation. Leukocytes are the major cellular mediators of inflammation and their elevated count is associated with higher CV event rate in ACS patients. Thus, it is possible that there is a relationship between hyperglycaemia and high leukocyte count among patients with ACS. Research Purpose: Aim of study is to investigate the relationship between hyperglycaemia and leukocyte count in ACS patients. Research Methods: This is a cross sectional study, which was held on January to April 2014 among 60 ACS patients in CVCU Wahidin Sudorohusodo Hospital. Glucose level and leukocyte count on admission were measured in 60 ACS patients. Patients was grouped into two groups, hyperglycemic ACS group (glycaemia on admission ≥ 140 mg/dL) and normoglycemic one (glycaemia on admission 140mg/dL). Leukocyte count was compared to hyperglycemia and normoglycemia patients. Reseaerch Result: Mean of leucocytes count was significantly different between normoglycaemia and hyperglycaemia ACS patients, both in all patients (9.34 ± 2.58 x 103 vs 13.63 ± 3.10 x 103, P0.0001) and in non DM patients (9.34 ± 2.58 x 103 vs 14.08 ± 3.20 x 103, P0.0001). There was no significant difference of mean leucocytes count between DM and non DM ACS patients admitted with hyperglicaemia (12.38 ± 2.54 x 103 vs 14.08 ± 3.20 x 103, P=0.121). Conclusion: The conclusion of this study was hyperglycaemia is assocciated with inflammatory status in ACS patients. Keywords:Acute coronary syndrome, hyperglycemia, and inflammation status

Collaboration network of the authors

15 authors · 22 co-authorship links · 6 across different organisations

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  • Universitas Halu Oleo
  • Universitas Muslim Indonesia
  • Universitas Cokroaminoto Palopo
  • Universitas Jambi
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Bahtiar BahtiarUniversitas Halu Oleo1
Sarmadan SarmadanAffiliation unknown1
Amiruddin EsoUniversitas Halu Oleo1
Nur JanaUniversitas Halu Oleo1
Arimaswati ArimaswatiUniversitas Halu Oleo1
Andy Rafdi Al BagizUniversitas Halu Oleo1
Fercee PrimulaUniversitas Halu Oleo1
Irawaty IrawatyAffiliation unknown1
Dina FitrianaUniversitas Halu Oleo1
Hilma YuniarAffiliation unknown1
Alfian NawirUniversitas Muslim Indonesia1
Emi Prasetyawati UmarUniversitas Muslim Indonesia1
Aryadi NurfalaqUniversitas Cokroaminoto Palopo1
Rikky HerdiyansyahUniversitas Jambi1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ojs.uho.ac.id/index.php/medula/oai, first harvested 31 Oct 2026, last seen 8 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">Hiperglikemia dan Status Inflamasi pada Pasien Sindroma Koroner Akut</dc:title>
	<dc:creator>Jamaluddin, Jamaluddin</dc:creator>
	<dc:description xml:lang="en-US">ABSTRACTBackground: Hyperglycaemia in patients with acute coronary syndromes (ACS) is associated with increased cardiovas­cular (CV) risk. Hyperglycaemia in patients with ACS may be associated with increased systemic inflammation. Leukocytes are the major cellular mediators of inflammation and their elevated count is associated with higher CV event rate in ACS patients. Thus, it is possible that there is a relationship between hyperglycaemia and high leukocyte count among patients with ACS. Research Purpose: Aim  of study is to investigate the relationship between hyperglycaemia and leukocyte count in ACS patients. Research Methods: This is a cross sectional study, which was held on January to April  2014 among 60 ACS patients in CVCU  Wahidin Sudorohusodo Hospital. Glucose level and leukocyte count on admission were measured in 60 ACS patients. Patients was grouped into two groups, hyperglycemic ACS group (glycaemia on admission ≥ 140 mg/dL) and normoglycemic one (glycaemia on admission  140mg/dL). Leukocyte count was compared to hyperglycemia and normoglycemia patients. Reseaerch Result: Mean of leucocytes count was significantly different between normoglycaemia and hyperglycaemia ACS patients, both in all patients (9.34 ± 2.58 x  103  vs 13.63 ± 3.10 x 103 ,  P0.0001) and in non DM patients (9.34 ± 2.58 x  103  vs 14.08 ± 3.20 x 103 ,  P0.0001). There was no significant difference of mean leucocytes count between DM and non DM ACS patients admitted with hyperglicaemia   (12.38 ± 2.54 x 103  vs 14.08 ± 3.20 x 103 ,  P=0.121). Conclusion: The conclusion of this study was hyperglycaemia is assocciated with inflammatory status in ACS patients. Keywords :Acute coronary syndrome, hyperglycemia, and inflammation status</dc:description>
	<dc:publisher xml:lang="en-US">Halu Oleo University</dc:publisher>
	<dc:contributor xml:lang="en-US"></dc:contributor>
	<dc:date>2019-05-13</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ojs.uho.ac.id/index.php/medula/article/view/6724</dc:identifier>
	<dc:identifier>10.46496/medula.v6i2.6724</dc:identifier>
	<dc:source xml:lang="en-US">MEDULA (JURNAL ILMIAH FAKULTAS KEDOKTERAN UNIVERSITAS HALU OLEO); Vol 6, No 2 (2019)</dc:source>
	<dc:source>2443-0218</dc:source>
	<dc:source>2339-1006</dc:source>
	<dc:source>10.46496/medula.v6i2</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ojs.uho.ac.id/index.php/medula/article/view/6724/4956</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2019 MEDULA</dc:rights>
</oai_dc:dc>