Melola Discovery

← Melola Discovery

Journal

Perbandingan Metode Proporsi dengan Metode Resazurin Microtiter Assay (Rema) untuk Deteksi Mycobacterium tuberculosis yang Resisten Terhadap Rifampisin

MEDULA (JURNAL ILMIAH FAKULTAS KEDOKTERAN UNIVERSITAS HALU OLEO) · Vol. 2 No. 2 (2017)

DOI
10.46496/medula.v2i2.2548
ISSN
2443-0218, 2339-1006
Published
2017-07-08
Publisher
Halu Oleo University
Language
eng

Abstract

Tuberculosis (TB) is one of the high infectious diseases in Indonesia caused by Mycobacteriumtuberculosis. Drugs which used for tuberculosis therapy has been widely reported experiencing resistance, while inappropriately treatment will lead to not effective and efficient care. Culture in Lowenstein Jensen medium is a gold standard to perform the drug susceptibility but it takes a long time to get results, therefore, new methods were developed to replace it, one of them is colorimetric method. This research aimed to compare Rifampicin susceptibility test in colorimetric method use REMA and culture method use Lowenstein Jensen medium. This study was a cross sectional with experimental laboratory design used 42 sputums from patients with tuberculosis, done at October 2010 until March 2011. In this research, 5 samples rifampicin resistant have been detected. As a results, we founded Rifampicin susceptibility test of REMA have 80 % sensitivity, 100 % specificity, 100 % PPV, and 97 % NPV when compared with culture method.Keywords:Proportion, Resazurin, Mycobacterium tuberculosis, Resistance

Collaboration network of the authors

40 authors · 113 co-authorship links · showing the 40 most connected

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

  • Hasanuddin University
  • Universitas Nusa Mandiri
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Subehan LalloAffiliation unknown4
M Natsir DjideAffiliation unknown4
Juminten SaiminAffiliation unknown3
Yulia Yusrini DjabirAffiliation unknown3
Gemini AlamAffiliation unknown3
Firzan NainuAffiliation unknown3
Waode Sitti Asfiah UduAffiliation unknown2
Nur Indah PurnamasariAffiliation unknown2
Sufiah Asri MulyawatiAffiliation unknown2
Asnah MarzukiAffiliation unknown2
Herlina RanteAffiliation unknown2
Emilia UtomoAffiliation unknown2
Ahyar AhmadHasanuddin University2
Dwi Agung PangestuUniversitas Nusa Mandiri1
Ade Surya BudimanAffiliation unknown1
Jumasni AdnanAffiliation unknown1
Mufidah MufidahAffiliation unknown1
Reski Yalatri WirastutyAffiliation unknown1
Sulfiyana H. Ambo LauAffiliation unknown1
Fauziah AminAffiliation unknown1
Nur Inda YantiAffiliation unknown1
Sumarheni SumarheniAffiliation unknown1
Andi Nur Zam ZamAffiliation unknown1
Latifah RahmanAffiliation unknown1
Andi Nurpati PanaungiAffiliation unknown1
Rahmasia RahmasiaAffiliation unknown1
Elly WahyudinAffiliation unknown1
Munawarah MunawarahAffiliation unknown1
Arif SantosoAffiliation unknown1
Muhammad Subhan A. SibaduAffiliation unknown1
Nurul Muhlisa MusAffiliation unknown1
SubehanAffiliation unknown1
Dedy Ma'rufAffiliation unknown1
Haeriah HaeriahAffiliation unknown1
Muhammad RahmatullahAffiliation unknown1
Andi IndardayaAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ojs.uho.ac.id/index.php/medula/oai, first harvested 31 Oct 2026, last seen 8 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Perbandingan Metode Proporsi dengan Metode Resazurin Microtiter Assay (Rema) untuk Deteksi Mycobacterium tuberculosis yang Resisten Terhadap Rifampisin</dc:title>
	<dc:creator>Purnamasari, Yenti</dc:creator>
	<dc:creator>Sartini, Sartini</dc:creator>
	<dc:creator>Attamimi, Faisal</dc:creator>
	<dc:creator>Massi, Muh. Nasrum</dc:creator>
	<dc:description xml:lang="en-US">Tuberculosis (TB) is one of the high infectious diseases in Indonesia caused by Mycobacteriumtuberculosis. Drugs which used for tuberculosis therapy has been widely reported experiencing resistance, while inappropriately treatment will lead to not effective and efficient care. Culture in Lowenstein Jensen medium is a gold standard to perform the drug susceptibility but it takes a long time to get results, therefore, new methods were developed to replace it, one of them is colorimetric method. This research aimed to compare Rifampicin susceptibility test in colorimetric method use REMA and culture method use Lowenstein Jensen medium. This study was a cross sectional with experimental laboratory design used 42 sputums from patients with tuberculosis, done at October 2010 until March 2011. In this research, 5 samples rifampicin resistant have been detected. As a results, we founded Rifampicin susceptibility test of REMA have 80 % sensitivity, 100 % specificity, 100 % PPV, and 97 % NPV when compared with culture method.Keywords:Proportion, Resazurin, Mycobacterium tuberculosis, Resistance</dc:description>
	<dc:publisher xml:lang="en-US">Halu Oleo University</dc:publisher>
	<dc:contributor xml:lang="en-US"></dc:contributor>
	<dc:date>2017-07-08</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ojs.uho.ac.id/index.php/medula/article/view/2548</dc:identifier>
	<dc:identifier>10.46496/medula.v2i2.2548</dc:identifier>
	<dc:source xml:lang="en-US">MEDULA (JURNAL ILMIAH FAKULTAS KEDOKTERAN UNIVERSITAS HALU OLEO); Vol 2, No 2 (2015)</dc:source>
	<dc:source>2443-0218</dc:source>
	<dc:source>2339-1006</dc:source>
	<dc:source>10.46496/medula.v2i2</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ojs.uho.ac.id/index.php/medula/article/view/2548/1896</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2017 Medula</dc:rights>
</oai_dc:dc>