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Analisis Pertumbuhan Kartilago Epifisialis Os Tibia Fetus Mencit (Mus musculus L.) Swiss Webster Setelah Induksi Ochratoxin A Selama Periode Organogenesis

JURNAL BIOLOGI PAPUA · Vol. 4 No. 1 (2018) · pp. 25–31

DOI
10.31957/jbp.532
ISSN
2503-0450, 2086-3314
Published
2018-10-14
Publisher
Jurusan Biologi FMIPA Universitas Cenderawasih
Language
eng

Abstract

The aims of this study were determined the effects of Ochratoxin A (OTA) on growth of fetus tibia epiphyseal cartilage during organogenesis period. Twenty four pregnant mice were divided randomly into 4 groups of 6. Ochratoxin A was dissolved in sodium bicarbonateand administered orally on seventh to fourteenth days of gestation at dosage of 0.5, 1.0, 1.5 mg/kg bw, respectively. The remaining were used as control. The fetal tibia was taken after the 18 th day of pregnancy. The growth of tibia epiphyseal cartilages were observed histologically using Erlich’s Haematoxylin-Eosin Stain. The result of this study indicated that OTA caused decreased thickness of the rest zone, proliferative zone, maturation zone and calsification zone of the fetus tibial growth plate significantly. Key words: Ochratoxin A, tibia, cartilage, and thickness.

Collaboration network of the authors

40 authors · 89 co-authorship links · 4 across different organisations · showing the 40 most connected

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

  • Universitas Gadjah Mada
  • Sriwijaya University
  • Universitas Negeri Surabaya
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Michael Haryadi WibowoAffiliation unknown4
Laila HanumSriwijaya University3
Wayan T. ArtamaAffiliation unknown3
Marsetyawan HNE SoesatyoAffiliation unknown2
Indra YustianAffiliation unknown2
Jaka WidadaUniversitas Gadjah Mada2
M. MustofaAffiliation unknown2
A. AlimuddinAffiliation unknown2
SEBASTIAN MARGINOAffiliation unknown2
W. WidodoUniversitas Negeri Surabaya2
Sri DarmawatiAffiliation unknown2
LANGKAH SEMBIRINGAffiliation unknown2
Tri UntariAffiliation unknown2
Elfita ElfitaAffiliation unknown2
Pinandi Sri PudyaniAffiliation unknown1
Ika Dewi AnaAffiliation unknown1
Tita Ratya UtariAffiliation unknown1
Siti SunarintyasAffiliation unknown1
Juni HandajaniAffiliation unknown1
Yulita KristantiAffiliation unknown1
Risya CilmiatyAffiliation unknown1
Mandojo RukmoAffiliation unknown1
Afiono Agung PrasetyoAffiliation unknown1
Khilyat Ulin Nur ZainiAffiliation unknown1
Suhartono Taat PutraAffiliation unknown1
Banun KusumawardaniAffiliation unknown1
Djaswadi DasukiAffiliation unknown1
Al. Supartinah SantosoAffiliation unknown1
Regina TC. TandelilinAffiliation unknown1
Abdul Salam M. SofroAffiliation unknown1
N NuryonoAffiliation unknown1
Dwi Aji NugrohoAffiliation unknown1
W. WidjijonoAffiliation unknown1
Wijayanti Dwi AastutiAffiliation unknown1
Dana ArdianataAffiliation unknown1
Suryani HutomoAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ejournal.uncen.ac.id/index.php/JBP/oai, first harvested 1 Nov 2026, last seen 8 Nov 2026.
Original metadata (oai_dc)
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	<dc:title xml:lang="en-US">Analisis Pertumbuhan Kartilago Epifisialis Os Tibia Fetus Mencit (Mus musculus L.) Swiss Webster Setelah Induksi Ochratoxin A Selama Periode Organogenesis</dc:title>
	<dc:creator>Setiawan, Arum</dc:creator>
	<dc:creator>Sagi, Mammed</dc:creator>
	<dc:creator>Asmara, Widya</dc:creator>
	<dc:creator>Istriyati, Istriyati</dc:creator>
	<dc:description xml:lang="en-US">The aims of this study were determined the effects of Ochratoxin A (OTA) on growth of fetus tibia epiphyseal cartilage during organogenesis period. Twenty four pregnant mice were divided randomly into 4 groups of 6. Ochratoxin A was dissolved in sodium bicarbonateand administered orally on seventh to fourteenth days of gestation at dosage of 0.5, 1.0, 1.5 mg/kg bw, respectively. The remaining were used as control. The fetal tibia was taken after the 18 th day of pregnancy. The growth of tibia epiphyseal cartilages were observed histologically using Erlich’s Haematoxylin-Eosin Stain. The result of this study indicated that OTA caused decreased thickness of the rest zone, proliferative zone, maturation zone and calsification zone of the fetus tibial growth plate significantly. Key words: Ochratoxin A, tibia, cartilage, and thickness.</dc:description>
	<dc:publisher xml:lang="en-US">Jurusan Biologi FMIPA Universitas Cenderawasih</dc:publisher>
	<dc:date>2018-10-14</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ejournal.uncen.ac.id/index.php/JBP/article/view/532</dc:identifier>
	<dc:identifier>10.31957/jbp.532</dc:identifier>
	<dc:source xml:lang="en-US">JURNAL BIOLOGI PAPUA; Vol. 4 No. 1 (2012); 25-31</dc:source>
	<dc:source xml:lang="id-ID">Jurnal Biologi Papua; Vol 4 No 1 (2012); 25-31</dc:source>
	<dc:source>2503-0450</dc:source>
	<dc:source>2086-3314</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ejournal.uncen.ac.id/index.php/JBP/article/view/532/468</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2018 JURNAL BIOLOGI PAPUA</dc:rights>
</oai_dc:dc>