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Kejadian Diabetus Melitus Pada Pasien Tuberkulosis di Kabupaten Brebes Tahun 2024

HIGEIA (Journal of Public Health Research and Development) · Vol. 9 No. 3 (2025) · pp. 207–215

DOI
10.15294/higeia.v9i3.28292
ISSN
2541-5603, 2541-5581
Published
2025-07-28
Publisher
Universitas Negeri Semarang
Language
eng

Abstract

Abstrak Komorbiditas antara tuberkulosis (TB) dan diabetes melitus (DM) menjadi tantangan serius dalam penanggulangan penyakit menular dan tidak menular, khususnya di wilayah dengan beban ganda seperti Kabupaten Brebes. Penelitian ini bertujuan untuk mengetahui prevalensi dan menganalisis faktor risiko yang berhubungan dengan kejadian DM pada pasien TB di Kabupaten Brebes tahun 2024. Desain penelitian yang digunakan adalah kuantitatif observasional analitik dengan pendekatan cross-sectional, melibatkan 1.315 pasien TB yang tercatat dalam Sistem Informasi Tuberkulosis (SITB). Analisis dilakukan secara univariat, bivariat(uji Chi-square), dan multivariat (regresi logistik). Hasil menunjukkan bahwa prevalensi DM pada pasien TB adalah 10,6%, dengan variabel usia ≥45 tahun (OR=5,278; CI 95%=2,970–9,380), lokasi anatomi TBC di paru-paru (OR=15,899; CI 95%=1,598–158,145), dan riwayat keluarga dengan DM (OR=99,389; CI 95%=54,448–181,424) sebagai determinan signifikan. Kesimpulan menunjukkan bahwa ketiga faktor tersebut berkontribusi besar terhadap kejadian DM pada pasien TB, dengan nilai determinasi model sebesar 61,4%. Penelitian ini memberikan kontribusi teoritis terhadap pemahaman hubungan imunologis antara penyakit menular dan metabolik, serta implikasi praktis bagi penguatan kebijakan skrining dan intervensi dini pada layanan TB-DM terintegrasi. Abstract The comorbidity between tuberculosis (TB) and diabetes mellitus (DM) poses a significant challenge in managing both communicable and non-communicable diseases, particularly in double burden areas such as Brebes District. This study aims to determine the prevalence and analyze risk factors associated with DM among TB patients in Brebes in 2024. A quantitative analytic observational study with a cross-sectional design was conducted using data from the TB Information System (SITB), involving 1,315 registered TB patients. Data were analyzed using univariate, bivariate (Chi-square test), and multivariate (logistic regression) methods. The prevalence of DM among TB patients was 10.6%. Significant risk factors included age ≥45 years (OR=5.278; 95% CI=2.970–9.380), pulmonary TB (OR=15.899; 95% CI=1.598–158.145), and family history of DM (OR=99.389; 95% CI=54.448–181.424). The model’s determination value was 61.4%. This study contributes theoretically to understanding the immunometabolic interaction between infectious and metabolic diseases, and practically to strengthening screening policies and early interventions in integrated TB-DM services.

Keywords

Collaboration network of the authors

40 authors · 70 co-authorship links · showing the 40 most connected

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  • Diponegoro University
  • State University of Semarang
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
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Co-authorOrganisationJoint articles
Nur SiyamAffiliation unknown3
Oktia Woro Kasmini HandayaniAffiliation unknown3
Evi WidowatiAffiliation unknown3
Intan ZainafreeAffiliation unknown3
Wandah WibawantoAffiliation unknown2
Margareta RahayuningsihAffiliation unknown2
Russiska RussiskaAffiliation unknown2
Ari YuniastutiState University of Semarang2
Dina Nur Anggraini NingrumAffiliation unknown2
Budi SantosoDiponegoro University1
Paramitha ParaningtyasDiponegoro University1
Adzan Fariq DarmawanAffiliation unknown1
Selvia Mayka SyahputriAffiliation unknown1
Karima Jafina Azka AnjaliAffiliation unknown1
Bertakalswa HermawatiAffiliation unknown1
Dyah Mahendrasari SukendraAffiliation unknown1
Yunita Dyah Puspita SantikAffiliation unknown1
Sherly GusnawanAffiliation unknown1
Hermi Nur LaelaAffiliation unknown1
Ika UtamiAffiliation unknown1
Tri Septa AnggrainiAffiliation unknown1
Arum SiwiendrayantiState University of Semarang1
Siti Ainun NadhirohAffiliation unknown1
Eka Radiyani OktaviaAffiliation unknown1
Fatehah Rahma AgustinAffiliation unknown1
Nandito Mapian MagaiAffiliation unknown1
Sigit Ambar WidyawatiAffiliation unknown1
Ni'mal MunaAffiliation unknown1
Mirnawati MirnawatiAffiliation unknown1
Nurfitriani NurfitrianiAffiliation unknown1
Febriana Maya ZulfiariniAffiliation unknown1
Merlinda Permata SariAffiliation unknown1
Tika MaelaniAffiliation unknown1
Karnowo HasanAffiliation unknown1
Tri WahyuniAffiliation unknown1
Susi NuryantiAffiliation unknown1
Habibah Yulia RestiAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://journal.unnes.ac.id/journals/HIGEIA/oai, first harvested 5 Nov 2026, last seen 5 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en">Kejadian Diabetus Melitus Pada Pasien Tuberkulosis di Kabupaten Brebes Tahun 2024</dc:title>
	<dc:creator xml:lang="en">Sibarani, Devita Uzlah</dc:creator>
	<dc:creator xml:lang="en">Riyanto, Agus</dc:creator>
	<dc:creator xml:lang="en">Cahyati, Widya Hary </dc:creator>
	<dc:subject xml:lang="en">faktor risiko</dc:subject>
	<dc:subject xml:lang="en">tuberkulosis</dc:subject>
	<dc:subject xml:lang="en">diabetes mellitus</dc:subject>
	<dc:subject xml:lang="en">komorbiditas</dc:subject>
	<dc:subject xml:lang="en">brebes</dc:subject>
	<dc:description xml:lang="en">Abstrak
Komorbiditas antara tuberkulosis (TB) dan diabetes melitus (DM) menjadi tantangan serius dalam penanggulangan penyakit menular dan tidak menular, khususnya di wilayah dengan beban ganda seperti Kabupaten Brebes. Penelitian ini bertujuan untuk mengetahui prevalensi dan menganalisis faktor risiko yang berhubungan dengan kejadian DM pada pasien TB di Kabupaten Brebes tahun 2024. Desain penelitian yang digunakan adalah kuantitatif observasional analitik dengan pendekatan cross-sectional, melibatkan 1.315 pasien TB yang tercatat dalam Sistem Informasi Tuberkulosis (SITB). Analisis dilakukan secara univariat, bivariat(uji Chi-square), dan multivariat (regresi logistik). Hasil menunjukkan bahwa prevalensi DM pada pasien TB adalah 10,6%, dengan variabel usia ≥45 tahun (OR=5,278; CI 95%=2,970–9,380), lokasi anatomi TBC di paru-paru (OR=15,899; CI 95%=1,598–158,145), dan riwayat keluarga dengan DM (OR=99,389; CI 95%=54,448–181,424) sebagai determinan signifikan. Kesimpulan menunjukkan bahwa ketiga faktor tersebut berkontribusi besar terhadap kejadian DM pada pasien TB, dengan nilai determinasi model sebesar 61,4%. Penelitian ini memberikan kontribusi teoritis terhadap pemahaman hubungan imunologis antara penyakit menular dan metabolik, serta implikasi praktis bagi penguatan kebijakan skrining dan intervensi dini pada layanan TB-DM terintegrasi.
 
Abstract
The comorbidity between tuberculosis (TB) and diabetes mellitus (DM) poses a significant challenge in managing both communicable and non-communicable diseases, particularly in double burden areas such as Brebes District. This study aims to determine the prevalence and analyze risk factors associated with DM among TB patients in Brebes in 2024. A quantitative analytic observational study with a cross-sectional design was conducted using data from the TB Information System (SITB), involving 1,315 registered TB patients. Data were analyzed using univariate, bivariate (Chi-square test), and multivariate (logistic regression) methods. The prevalence of DM among TB patients was 10.6%. Significant risk factors included age ≥45 years (OR=5.278; 95% CI=2.970–9.380), pulmonary TB (OR=15.899; 95% CI=1.598–158.145), and family history of DM (OR=99.389; 95% CI=54.448–181.424). The model’s determination value was 61.4%. This study contributes theoretically to understanding the immunometabolic interaction between infectious and metabolic diseases, and practically to strengthening screening policies and early interventions in integrated TB-DM services.</dc:description>
	<dc:publisher xml:lang="en">Universitas Negeri Semarang</dc:publisher>
	<dc:date>2025-07-28</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unnes.ac.id/journals/HIGEIA/article/view/28292</dc:identifier>
	<dc:identifier>10.15294/higeia.v9i3.28292</dc:identifier>
	<dc:source xml:lang="en">HIGEIA (Journal of Public Health Research and Development); Vol. 9 No. 3 (2025): July 2025; 207-215</dc:source>
	<dc:source>2541-5603</dc:source>
	<dc:source>2541-5581</dc:source>
	<dc:source>10.15294/higeia.v9i3</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journal.unnes.ac.id/journals/HIGEIA/article/view/28292/11931</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2026 HIGEIA (Journal of Public Health Research and Development)</dc:rights>
</oai_dc:dc>