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The The Effect Of Uncontrolled Addition Of Gelatin In Paracetamol Tablet Formulation And The Evaluation

Journal of Science and Technology Research for Pharmacy · Vol. 2 No. 1 (2023) · pp. 31–37

DOI
10.15294/jstrp.v2i1.57436
ISSN
2776-0685
Published
2023-05-05
Publisher
Universitas Negeri Semarang
Language
eng

Abstract

Acetaminophen is a pain-relieving (analgesic) and fever-treating (antipyretic) medication that can be obtained over-the-counter. Wet granulation evaluation of granule among others flow time, angle of repose, tapped density tableting evaluation tablet among others weight uniformity, friability, disintegration time tablet flow time evaluation test was 0.16 with an angle of repose 51.78 tapped density of 30%. Tablet manufacturing process, tablet was damaged during the initial printing, namely capping. The tablet evaluation test obtained weight uniformity 248mg, friability 3.22%, disintegration time 1 minute, dissolution results at 60th minutes is 2.2817. The formulation of paracetamol tablets made by the researchers did not meet the specifications for marketability, where the discrepancy in tablet specifications occurred in the physical and chemical properties of the tablets.

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Siti Harnina Bintari BintariAffiliation unknown1

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Metadata source: OAI-PMH (metadata jurnal) https://journal.unnes.ac.id/sju/index.php/JSTRP/oai, first harvested 5 Nov 2026, last seen 5 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">The The Effect Of Uncontrolled Addition Of Gelatin In Paracetamol Tablet Formulation And The Evaluation</dc:title>
	<dc:creator>Putri, Nanda Sabila Fitriana</dc:creator>
	<dc:description xml:lang="en-US">Acetaminophen is a pain-relieving (analgesic) and fever-treating (antipyretic) medication that&amp;nbsp;can be obtained over-the-counter. Wet granulation evaluation of granule among others flow&amp;nbsp;time, angle of repose, tapped density tableting evaluation tablet among others weight&amp;nbsp;uniformity, friability, disintegration time tablet flow time evaluation test was 0.16 with an&amp;nbsp;angle of repose 51.78 tapped density of 30%. Tablet manufacturing process, tablet was&amp;nbsp;damaged during the initial printing, namely capping. The tablet evaluation test obtained&amp;nbsp;weight uniformity 248mg, friability 3.22%, disintegration time 1 minute, dissolution results&amp;nbsp;at 60th minutes is 2.2817. The formulation of paracetamol tablets made by the researchers did&amp;nbsp;not meet the specifications for marketability, where the discrepancy in tablet specifications&amp;nbsp;occurred in the physical and chemical properties of the tablets.</dc:description>
	<dc:publisher xml:lang="en-US">Universitas Negeri Semarang</dc:publisher>
	<dc:date>2023-05-05</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US">Peer-reviewed Article</dc:type>
	<dc:type xml:lang="en-US">Text</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.unnes.ac.id/sju/JSTRP/article/view/57436</dc:identifier>
	<dc:identifier>10.15294/jstrp.v2i1.57436</dc:identifier>
	<dc:source xml:lang="en-US">Journal of Science and Technology Research for Pharmacy; Vol 2 No 1 (2022); 31-37</dc:source>
	<dc:source>2776-0685</dc:source>
	<dc:source>10.15294/jstrp.v2i1</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journal.unnes.ac.id/sju/JSTRP/article/view/57436/24187</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2023 Journal of Science and Technology Research for Pharmacy</dc:rights>
</oai_dc:dc>