Journal
Fructone Synthesis from Ethanol and Acetic Acid
Indonesian Journal of Chemical Science · Vol. 11 No. 3 (2022) · pp. 250–258
- ISSN
- 2502-6844, 2252-6951
- Published
- 2022-11-01
- Publisher
- Universitas Negeri Semarang
- Language
- eng
Abstract
Fructone (Ethyl 2-methyl-1,3-dioxolan-2-acetate) is a perfume ingredient with an apple scent. This study aims to synthesize fructone through the steps of synthesizing ethyl acetate from ethanol and acetic acid, synthesizing ethyl acetoacetate from ethyl acetate through the Claisen condensation reaction, and synthesizing fructone through the acetylation reaction of ethyl acetoacetate with ethylene glycol. Determination of the optimum conditions for the reaction is done by varying the temperature, reagents, catalysts, and time. The reaction products were analyzed by GC and GCMS. It was found that the conversion of ethyl acetate with H2SO4 catalyst and p-toluene sulfonic acid (PTSA) at 75 oC was almost the same, namely 96.63% for H2SO4 catalyst and 96.02% for PTSA catalyst. The optimum conditions for the synthesis of ethyl acetoacetate at a temperature of 82 oC, mole ratio of ethyl acetate, ethanol, and sodium 2:1:1, reaction time for 2 hours with ethyl acetoacetate conversion of 91,55%. The fructone formation reaction using the cyclohexane-water azeotrope technique gave more product than without using the azeotrope technique. The optimum condition for the synthesis of fructone compounds at a temperature of 78 oC, the ratio of moles of ethyl acetoacetate, ethylene glycol and H2SO4 catalyst is 1:2:0.06, the reaction time is 2 hours with the resulting fructone conversion of 87.07%.
Collaboration network of the authors
35 authors · 103 co-authorship links · 1 across different organisations
Hover or tap a name to highlight its co-authors. Double-click to open the author's page.
- Indonesia University of Education
- Sebelas Maret University
- Affiliation unknown
- Different organisations
- Same organisation
- Affiliation unknown
- Thicker line = more joint articles · bigger circle = more articles
Show as table
| Co-author | Organisation | Joint articles |
|---|---|---|
| Norazilawati Abdullah | Affiliation unknown | 2 |
| Siti Aisyah | Affiliation unknown | 1 |
| Asyti Febliza | Affiliation unknown | 1 |
| Lusia Narsia Amsad | Affiliation unknown | 1 |
| Liliasari S | Affiliation unknown | 1 |
| Ratnaningsih Eko Sardjono | Affiliation unknown | 1 |
| Ardi Ardi | Affiliation unknown | 1 |
| Muhammad Akil | Affiliation unknown | 1 |
| Said Syaripuddin | Affiliation unknown | 1 |
| M. Hasibuddin | Affiliation unknown | 1 |
| Wahyu Sopandi | Indonesia University of Education | 1 |
| Yuli Handayanti | Affiliation unknown | 1 |
| Ratulani Juwita | Affiliation unknown | 1 |
| Heli Siti Halimatul Munawaroh | Affiliation unknown | 1 |
| Ratnaningsih Eko S. | Affiliation unknown | 1 |
| Gebi Dwiyanti | Affiliation unknown | 1 |
| Lela Lailatul K. | Affiliation unknown | 1 |
| Ede Kadarusman | Affiliation unknown | 1 |
| Ahmad Nur F. | Affiliation unknown | 1 |
| Liliasari Liliasari | Indonesia University of Education | 1 |
| M. Setyarini | Affiliation unknown | 1 |
| Muhamad A. Martoprawiro | Affiliation unknown | 1 |
| Hernani Hernani | Indonesia University of Education | 1 |
| Ika Nur Fitriani | Sebelas Maret University | 1 |
| Anita Fibonacci | Affiliation unknown | 1 |
Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.