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EFFECTS OF QUR’AN RECITATION ON LEFT VENTRICULAR OUTFLOW TRACT VELOCITY TIME INTEGRAL IN PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION

Jurnal Ilmiah Islam Futura · Vol. 25 No. 2 (2025) · pp. 435–449

DOI
10.22373/jiif.v25.i2.32311
ISSN
2407-7542, 1412-1190
Published
2025-08-19
Publisher
Universitas Islam Negeri Ar-Raniry
Language
eng
License
creativecommons.org/licenses/by/4.0/

Abstract

Left ventricular outflow tract velocity time integral (LVOT-VTI) is a noninvasive echocardiographic parameter representing stroke volume. Qur’an recitation has been reported to influence cardiovascular indicators such as heart rate variability and blood pressure, which are indirectly related to cardiac function, although its effect on direct echocardiographic parameters remains unclear. This study aimed to evaluate whether patients with heart failure with reduced ejection fraction (HFrEF) show improvement in cardiac function, as reflected by changes in LVOT-VTI, following Qur’an recitation. A case-control study was conducted involving 30 HFrEF patients divided into three groups: Group 1 recited one juz of the Qur’an daily, Group 2 recited half a juz daily, and Group 3 served as a control. Echocardiographic measurements of LVOT-VTI and ejection fraction (EF) were performed at baseline and after 30 days. Significant improvements in EF were observed in Groups 1 and 2 (p = 0.000), while no significant change was found in the control group (p = 0.260). LVOT-VTI increased significantly in Groups 1 and 2 (p = 0.020) but not in Group 3 (p = 0.090). LVOT-VTI is an independent prognostic marker in HFrEF, and these findings support further well-designed clinical trials to evaluate the clinical benefits of Qur’an recitation.

Keywords

Collaboration network of the authors

39 authors · 70 co-authorship links

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  • Universitas Halu Oleo
  • Institut Agama Islam Negeri Kendari
  • Affiliation unknown
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Co-authorOrganisationJoint articles
Mirza AntoniAffiliation unknown2
Lia Perwita SariAffiliation unknown2
RiswaniAffiliation unknown2
Nur PaikahAffiliation unknown2
Natalis RansiUniversitas Halu Oleo1
Waode Hardianas ShalawatiAffiliation unknown1
Sulastrianah SulastrianahAffiliation unknown1
Eka Suci FitriaAffiliation unknown1
Lifianthi LifianthiAffiliation unknown1
Deswita Fajar AyuningsihAffiliation unknown1
Hanapi UsmanAffiliation unknown1
Nunuk Hariani SoekamtoAffiliation unknown1
Andi Tenri AmpaInstitut Agama Islam Negeri Kendari1
NurlianaAffiliation unknown1
Maghfirah Sari AzisAffiliation unknown1
Syakir SyakirAffiliation unknown1
Eko SugiartoAffiliation unknown1
Iwan RamadhanAffiliation unknown1
Muhammad Agus HardiansyahAffiliation unknown1
Muhajirul FadhliAffiliation unknown1
Juwaini JuwainiAffiliation unknown1
Nurul MawaddahAffiliation unknown1
M. ChalisAffiliation unknown1
Muhammad RizqiyAffiliation unknown1
Raina WildanAffiliation unknown1
Kasyiful AkmaliaAffiliation unknown1
T. Lembong MisbahAffiliation unknown1
Faissal MalikAffiliation unknown1
Abdullah Akhyar NasutionAffiliation unknown1
Ibrahim ChalidAffiliation unknown1
Samsul BahriAffiliation unknown1
Muhammad RizkiAffiliation unknown1
Maizuddin MaizuddinAffiliation unknown1
Siti Hajril MasyithahAffiliation unknown1
Nur HafniAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://jurnal.ar-raniry.ac.id/index.php/islamfutura/oai, first harvested 6 Nov 2026, last seen 6 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">EFFECTS OF QUR’AN RECITATION ON LEFT VENTRICULAR OUTFLOW TRACT VELOCITY TIME INTEGRAL IN PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION</dc:title>
	<dc:creator xml:lang="en">Nurkhalis, Nurkhalis</dc:creator>
	<dc:creator xml:lang="en">Jamil, Kurnia  Fitri</dc:creator>
	<dc:creator xml:lang="en">Imran, Imran</dc:creator>
	<dc:creator xml:lang="en">Yamin, Muhammad </dc:creator>
	<dc:subject xml:lang="en">Left ventricular outflow tract velocity time integral</dc:subject>
	<dc:subject xml:lang="en">Heart rate variability</dc:subject>
	<dc:subject xml:lang="en">Qur’an</dc:subject>
	<dc:subject xml:lang="en">Heart failure with reduced ejection fraction</dc:subject>
	<dc:subject xml:lang="en">cardiac function</dc:subject>
	<dc:description xml:lang="en">Left ventricular outflow tract velocity time integral (LVOT-VTI) is a noninvasive echocardiographic parameter representing stroke volume. Qur’an recitation has been reported to influence cardiovascular indicators such as heart rate variability and blood pressure, which are indirectly related to cardiac function, although its effect on direct echocardiographic parameters remains unclear. This study aimed to evaluate whether patients with heart failure with reduced ejection fraction (HFrEF) show improvement in cardiac function, as reflected by changes in LVOT-VTI, following Qur’an recitation. A case-control study was conducted involving 30 HFrEF patients divided into three groups: Group 1 recited one juz of the Qur’an daily, Group 2 recited half a juz daily, and Group 3 served as a control. Echocardiographic measurements of LVOT-VTI and ejection fraction (EF) were performed at baseline and after 30 days. Significant improvements in EF were observed in Groups 1 and 2 (p = 0.000), while no significant change was found in the control group (p = 0.260). LVOT-VTI increased significantly in Groups 1 and 2 (p = 0.020) but not in Group 3 (p = 0.090). LVOT-VTI is an independent prognostic marker in HFrEF, and these findings support further well-designed clinical trials to evaluate the clinical benefits of Qur’an recitation.</dc:description>
	<dc:publisher xml:lang="en">Universitas Islam Negeri Ar-Raniry</dc:publisher>
	<dc:date>2025-08-19</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://jurnal.ar-raniry.ac.id/index.php/islamfutura/article/view/32311</dc:identifier>
	<dc:identifier>10.22373/jiif.v25.i2.32311</dc:identifier>
	<dc:source xml:lang="en">Jurnal Ilmiah Islam Futura; Vol. 25 No. 2 (2025): Jurnal Ilmiah Islam Futura; 435-449</dc:source>
	<dc:source xml:lang="id">Islam Futura; Vol 25 No 2 (2025): Jurnal Ilmiah Islam Futura; 435-449</dc:source>
	<dc:source>2407-7542</dc:source>
	<dc:source>1412-1190</dc:source>
	<dc:source>10.22373/jiif.v25i2</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://jurnal.ar-raniry.ac.id/index.php/islamfutura/article/view/32311/12481</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2025 dr. Nurkhalis, Sp.JP-FIHA,FAsCC, Prof. Dr. dr. H. Kurnia Fitri Jamil, M.Kes, Sp.PD-KPTI, FINASIM, Dr.dr. Imran SpS(K), M.Kes, Dr.dr. Muhammad Yamin, SpJP(K), SpPD</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by/4.0/</dc:rights>
</oai_dc:dc>