Risk Factors for the Incidence of Drug-Resistant Tuberculosis in the Labuang Baji Hospital: A Healthpreneur Perspective

Rahmat, Afiyah Mahdiyah; Noor, Nur Nasry; Maria, Ida Leida; Davies, George

doi:10.34306/att.v6i3.394

Open access Journal

Risk Factors for the Incidence of Drug-Resistant Tuberculosis in the Labuang Baji Hospital: A Healthpreneur Perspective

Aptisi Transactions on Technopreneurship (ATT) · Vol. 6 No. 3 (2024) · pp. 468–480

DOI: 10.34306/att.v6i3.394
ISSN: 2656-8888, 2655-8807
Published: 2024-11-17
Publisher: Pandawan
Language: en
License: creativecommons.org/licenses/by/4.0

Abstract

Tuberculosis (TB) caused by Mycobacterium tuberculosis, remains a global health challenge, with drug-resistant TB (TB-RO) posing significant risks to control efforts. This study aims to identify risk factors associated with TB-RO among patients at Labuang Baji Makassar Hospital, Indonesia. Conducted from September to October 2023, this analytical case-control study utilized a quantitative approach. Data were collected from the Tuberculosis Information System (SITB) and hospital medical records, involving all TB-RO patients under treatment between 2022 and 2023. Total sampling yielded 105 cases, with analysis performed using univariate, bivariate, and multivariate methods. Results indicate that age (OR=2.509, CI 95%: 1.120–5.622; p=0.036), positive BTA sputum (OR=3.397, CI 95%: 1.630–7.082; p=0.001), and prior treatment history (OR=0.461, CI 95%: 0.254–0.837; p=0.016) are significant factors. Positive BTA sputum emerged as the dominant risk. Findings suggest that inadequate treatment adherence may contribute to TB-RO incidence. The study concludes that age and BTA phlegm are key risk factors, while a history of successful treatment is protective. Strengthening patient monitoring and ensuring treatment compliance are essential for mitigating TB-RO risk and improving outcomes.

Keywords

Collaboration network of the authors

10 authors · 15 co-authorship links

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

Affiliation unknown

Different organisations
Same organisation
Affiliation unknown
Thicker line = more joint articles · bigger circle = more articles

Show as table

Co-author	Organisation	Joint articles
Dhilah Harfadhilah	Affiliation unknown	1
I Nyoman Sunarka	Affiliation unknown	1
I Putu Sudayasa	Affiliation unknown	1
Muhammad Rizal Ardiansyah	Affiliation unknown	1
Firda Nurul Fadilah Farid	Affiliation unknown	1
Rismayanti Rismayanti	Affiliation unknown	1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://att.aptisi.or.id/index.php/att/oai, first harvested 6 Nov 2026, last seen 6 Nov 2026.

Original metadata (oai_dc)

<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Risk Factors for the Incidence of Drug-Resistant Tuberculosis in the Labuang Baji Hospital: A Healthpreneur Perspective</dc:title>
	<dc:creator xml:lang="en">Rahmat, Afiyah Mahdiyah</dc:creator>
	<dc:creator xml:lang="en">Noor, Nur Nasry</dc:creator>
	<dc:creator xml:lang="en">Maria, Ida Leida</dc:creator>
	<dc:creator xml:lang="en">Davies, George</dc:creator>
	<dc:subject xml:lang="en">Drug-Resistant Tuberculosis</dc:subject>
	<dc:subject xml:lang="en">Risk Factors</dc:subject>
	<dc:subject xml:lang="en">Labuang Baji Hospital</dc:subject>
	<dc:description xml:lang="en">Tuberculosis (TB) caused by Mycobacterium tuberculosis, remains a global health challenge, with drug-resistant TB (TB-RO) posing significant risks to control efforts. This study aims to identify risk factors associated with TB-RO among patients at Labuang Baji Makassar Hospital, Indonesia. Conducted from September to October 2023, this analytical case-control study utilized a quantitative approach. Data were collected from the Tuberculosis Information System (SITB) and hospital medical records, involving all TB-RO patients under treatment between 2022 and 2023. Total sampling yielded 105 cases, with analysis performed using univariate, bivariate, and multivariate methods. Results indicate that age (OR=2.509, CI 95%: 1.120–5.622; p=0.036), positive BTA sputum (OR=3.397, CI 95%: 1.630–7.082; p=0.001), and prior treatment history (OR=0.461, CI 95%: 0.254–0.837; p=0.016) are significant factors. Positive BTA sputum emerged as the dominant risk. Findings suggest that inadequate treatment adherence may contribute to TB-RO incidence. The study concludes that age and BTA phlegm are key risk factors, while a history of successful treatment is protective. Strengthening patient monitoring and ensuring treatment compliance are essential for mitigating TB-RO risk and improving outcomes.</dc:description>
	<dc:publisher xml:lang="en">Pandawan</dc:publisher>
	<dc:date>2024-11-17</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://att.aptisi.or.id/index.php/att/article/view/394</dc:identifier>
	<dc:identifier>10.34306/att.v6i3.394</dc:identifier>
	<dc:source xml:lang="en">Aptisi Transactions on Technopreneurship (ATT); Vol. 6 No. 3 (2024): November; 468-480</dc:source>
	<dc:source xml:lang="id">Aptisi Transactions On Technopreneurship (ATT); Vol 6 No 3 (2024): November; 468-480</dc:source>
	<dc:source>2656-8888</dc:source>
	<dc:source>2655-8807</dc:source>
	<dc:source>10.34306/att.v6i3</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://att.aptisi.or.id/index.php/att/article/view/394/289</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2024 Afiyah Mahdiyah Rahmat, Nur Nasry Noor, Ida Leida Maria, George Davies</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by/4.0</dc:rights>
</oai_dc:dc>