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DETECTION OF MecC GENE OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS ISOLATES AT JAMBI CITY HOSPITALS

Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan · Vol. 11 No. 1 (2023) · pp. 10–15

DOI
10.22437/jmj.v11i1.23910
ISSN
2580-6874, 2339-269X
Published
2023-06-02
Publisher
FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI
Language
en

Abstract

Background: Methicillin Resistant Staphylococcus aureus (MRSA) has a low-affinity to penicillinbinding protein (PBP) in B1subclass, and is often known as PBP2a or PBP2, characterized by the presence of mecA gene. Further research found MRSA isolates that did not contain the mecA gene. They have mecA homolog gene (mecALGA251) which has similarity with the classic mecA gene, then named the mecC gene. The discovery of MRSA mecC in humans still low in prevalence.Objective: This study aimed to detect mecC gene in MRSA isolates at hospitals in Jambi.Method: This study was a descriptive study conducted in the Biomedical and Biomolecular Laboratoryof Faculty of Medicine and Health Sciences, Jambi University.Results: A total of 117 clinical specimens in the forms of purulent wound swabs of the inpatients athospitals in Jambi City has been cultured on the MSA agar. Then yellowish samples (43 isolates) were screened for susceptibity of cefoxitin (30 µg) by disc / diffusion test and the presence of mecA, femB and mecC genes by conventional PCR. There were 22 (51.16%) samples contained mecA, 2 (4.65%) samples had also femB gen, 1 (2.32%) samples contained femB gene only and none contained the mecC gene.Conclusion: There was no mecC gene had been found in MRSA isolates in Jambi.Keywords: PCR, MRSA, MecC, MecA, FemB

Collaboration network of the authors

40 authors · 195 co-authorship links · showing the 40 most connected

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  • Universitas Halu Oleo
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Tengku Arief Buana PerkasaAffiliation unknown5
Fathnur Sani KasmadiAffiliation unknown5
LipinwatiAffiliation unknown2
Wilia Novita Eka RiniAffiliation unknown2
AsparianAffiliation unknown2
Hasna DewiAffiliation unknown2
Huntari HarahapAffiliation unknown2
FitriyantiAffiliation unknown2
Rakhmi Aisyah El MawaddahAffiliation unknown1
Ummi KalsumAffiliation unknown1
HafizahAffiliation unknown1
Fadliyana EkawatyAffiliation unknown1
Denok Tri HardiningsihAffiliation unknown1
Rita HalimAffiliation unknown1
Raihanah SuzanAffiliation unknown1
Rizma Adlia SyakurahAffiliation unknown1
Rahmatillah RazakAffiliation unknown1
Armaidi DarmawanAffiliation unknown1
Esa Indah AyudiaAffiliation unknown1
MiftahurrahmaAffiliation unknown1
Wahyu Indah AuroraAffiliation unknown1
Muhammad SyukriUniversitas Halu Oleo1
Andy AmirAffiliation unknown1
Rizalia WardiahAffiliation unknown1
GuspiantoAffiliation unknown1
Raihana SuzanAffiliation unknown1
Budi JustitiaAffiliation unknown1
Attiya IstariniAffiliation unknown1
Rts Netisa MartawinartiAffiliation unknown1
NurhusnaAffiliation unknown1
Kintan Resqitha EkaputriAffiliation unknown1
Wahyu Indah Dewi AuroraAffiliation unknown1
Rina Nofri EnisAffiliation unknown1
Zahra Frizki AstyAffiliation unknown1
guspianto guspiantoAffiliation unknown1
Ekawati Yun NinaAffiliation unknown1
Ilhami MohamadAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://online-journal.unja.ac.id/index.php/kedokteran/oai, first harvested 6 Nov 2026, last seen 8 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en">DETECTION OF MecC GENE OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS ISOLATES  AT JAMBI CITY HOSPITALS</dc:title>
	<dc:creator xml:lang="en">Humaryanto</dc:creator>
	<dc:creator xml:lang="en">Fairuz</dc:creator>
	<dc:creator xml:lang="en">Hanina</dc:creator>
	<dc:description xml:lang="en"> Background: Methicillin Resistant Staphylococcus aureus (MRSA) has a low-affinity to penicillinbinding protein (PBP) in B1subclass, and is often known as PBP2a or PBP2, characterized by the presence of mecA gene. Further research found MRSA isolates that did not contain the mecA gene. They have mecA homolog gene (mecALGA251) which has similarity with the classic mecA gene, then named the mecC gene. The discovery of MRSA mecC in humans still low in prevalence.Objective: This study aimed to detect mecC gene in MRSA isolates at hospitals in Jambi.Method: This study was a descriptive study conducted in the Biomedical and Biomolecular Laboratoryof Faculty of Medicine and Health Sciences, Jambi University.Results: A total of 117 clinical specimens in the forms of purulent wound swabs of the inpatients athospitals in Jambi City has been cultured on the MSA agar. Then yellowish samples (43 isolates) were screened for susceptibity of cefoxitin (30 µg) by disc / diffusion test and the presence of mecA, femB and mecC genes by conventional PCR. There were 22 (51.16%) samples contained mecA, 2 (4.65%) samples had also femB gen, 1 (2.32%) samples contained femB gene only and none contained the mecC gene.Conclusion: There was no mecC gene had been found in MRSA isolates in Jambi.Keywords: PCR, MRSA, MecC, MecA, FemB </dc:description>
	<dc:publisher xml:lang="en">FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI</dc:publisher>
	<dc:date>2023-06-02</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
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	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://online-journal.unja.ac.id/kedokteran/article/view/23910</dc:identifier>
	<dc:identifier>10.22437/jmj.v11i1.23910</dc:identifier>
	<dc:source xml:lang="en">Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan; Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan ; 10-15</dc:source>
	<dc:source>2580-6874</dc:source>
	<dc:source>2339-269X</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://online-journal.unja.ac.id/kedokteran/article/view/23910/15613</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2023 JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan"</dc:rights>
</oai_dc:dc>