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Knowledge and Treatment Adherence as Determinants in the Control of HIV/AIDS: A Social Epidemiology Approach

Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan · Vol. 13 No. 2 (2025) · pp. 216–224

DOI
10.22437/jmj.v13i2.49121
ISSN
2580-6874, 2339-269X
Published
2025-11-10
Publisher
FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI
Language
en

Abstract

Background: HIV/AIDS remains a major public health challenge worldwide, and treatment adherence continues to be a critical factor in achieving effective viral suppression. Knowledge about HIV prevention plays a vital role in shaping health behaviors and promoting adherence to antiretroviral therapy (ART). This study aimed to analyze the association between knowledge of HIV prevention and treatment adherence among people living with HIV/AIDS (PLWHA) using a social epidemiology framework. Methods: A cross-sectional quantitative study was conducted among 101 PLWHA receiving ART in public health centers and clinics. Data were collected through structured questionnaires covering demographic characteristics, knowledge of HIV prevention, and treatment adherence, verified with medical records. Data were analyzed using descriptive statistics and the Chi-square test (α =.05) to assess the relationship between knowledge and adherence levels. Results: The majority of respondents were male (82.2%) and had completed secondary education (66.3%). Most participants demonstrated fair to good levels of HIV prevention knowledge; however, adherence levels varied. The Chi-square test revealed a highly significant association between knowledge and treatment adherence, χ²(4) = 202, p <.001, indicating that higher knowledge was strongly correlated with improved adherence. Conclusion: The findings emphasize that knowledge enhancement significantly improves ART adherence and contributes to the control of HIV/AIDS. Strengthening education programs, peer support, and community engagement are essential strategies to foster sustainable adherence and align national efforts with global HIV prevention targets.

Keywords

Collaboration network of the authors

40 authors · 275 co-authorship links · showing the 40 most connected

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  • Universitas Jambi
  • Affiliation unknown
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Co-authorOrganisationJoint articles
Nuriyah NuriyahAffiliation unknown33
Andika SulistiawanAffiliation unknown16
Nyimas Natasha Ayu ShafiraAffiliation unknown14
Anggelia PuspasariAffiliation unknown14
Huntari HarahapAffiliation unknown14
Amelia Dwi FitriAffiliation unknown13
Rina Nofri EnisAffiliation unknown13
Herlambang HerlambangUniversitas Jambi12
Citra MaharaniAffiliation unknown11
Mirna Marhami IskandarAffiliation unknown10
Tengku Arief Buana PerkasaAffiliation unknown9
NuriyahAffiliation unknown8
Maria Estela KarolinaAffiliation unknown7
Mara Imam Taufiq SiregarAffiliation unknown7
Tia Wida EkaputriAffiliation unknown6
Raihanah SuzanAffiliation unknown6
Asro Hayani HarahapAffiliation unknown5
Ratna SugiartiAffiliation unknown5
Ave Olivia RahmanAffiliation unknown5
LipinwatiAffiliation unknown5
Attiya IstariniAffiliation unknown4
Irawan Anasta PutraAffiliation unknown4
Rita HalimAffiliation unknown4
Humaryanto HumaryantoAffiliation unknown4
Hanina HaninaAffiliation unknown4
Hasna DewiAffiliation unknown4
Susan TarawifaAffiliation unknown4
Diana Nur AfifahAffiliation unknown3
Gemala AnjaniAffiliation unknown3
Jurnal JMJAffiliation unknown3
Esa Indah AyudiaAffiliation unknown3
Fairuz FairuzAffiliation unknown2

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://online-journal.unja.ac.id/index.php/kedokteran/oai, first harvested 6 Nov 2026, last seen 8 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en">Knowledge and Treatment Adherence as Determinants in the Control of HIV/AIDS: A Social Epidemiology Approach</dc:title>
	<dc:creator xml:lang="en">Kusdiyah, Erny</dc:creator>
	<dc:creator xml:lang="en">aurora, Wahyu Indah Dewi</dc:creator>
	<dc:creator xml:lang="en">Syauqy, Ahmad</dc:creator>
	<dc:creator xml:lang="en">Miftahurrahmah, Miftahurrahmah</dc:creator>
	<dc:creator xml:lang="en">Wulandari, Putri Sari</dc:creator>
	<dc:creator xml:lang="en">Maria, Ima</dc:creator>
	<dc:creator xml:lang="en">Darmawan, Armaidi</dc:creator>
	<dc:creator xml:lang="id">Aurora</dc:creator>
	<dc:subject xml:lang="en">HIV/AIDS</dc:subject>
	<dc:subject xml:lang="en">Knowledge</dc:subject>
	<dc:subject xml:lang="en">Treatment Adherence</dc:subject>
	<dc:subject xml:lang="en">Antiretroviral Therapy</dc:subject>
	<dc:subject xml:lang="en">Social Epidemiology</dc:subject>
	<dc:description xml:lang="en">Background: HIV/AIDS remains a major public health challenge worldwide, and treatment adherence continues to be a critical factor in achieving effective viral suppression. Knowledge about HIV prevention plays a vital role in shaping health behaviors and promoting adherence to antiretroviral therapy (ART). This study aimed to analyze the association between knowledge of HIV prevention and treatment adherence among people living with HIV/AIDS (PLWHA) using a social epidemiology framework.
Methods: A cross-sectional quantitative study was conducted among 101 PLWHA receiving ART in public health centers and clinics. Data were collected through structured questionnaires covering demographic characteristics, knowledge of HIV prevention, and treatment adherence, verified with medical records. Data were analyzed using descriptive statistics and the Chi-square test (α = .05) to assess the relationship between knowledge and adherence levels.
Results: The majority of respondents were male (82.2%) and had completed secondary education (66.3%). Most participants demonstrated fair to good levels of HIV prevention knowledge; however, adherence levels varied. The Chi-square test revealed a highly significant association between knowledge and treatment adherence, χ²(4) = 202, p &amp;lt; .001, indicating that higher knowledge was strongly correlated with improved adherence.
Conclusion: The findings emphasize that knowledge enhancement significantly improves ART adherence and contributes to the control of HIV/AIDS. Strengthening education programs, peer support, and community engagement are essential strategies to foster sustainable adherence and align national efforts with global HIV prevention targets.</dc:description>
	<dc:publisher xml:lang="en">FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI</dc:publisher>
	<dc:date>2025-11-10</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://online-journal.unja.ac.id/kedokteran/article/view/49121</dc:identifier>
	<dc:identifier>10.22437/jmj.v13i2.49121</dc:identifier>
	<dc:source xml:lang="en">Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan; Vol. 13 No. 2 (2025): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan; 216-224</dc:source>
	<dc:source>2580-6874</dc:source>
	<dc:source>2339-269X</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://online-journal.unja.ac.id/kedokteran/article/view/49121/22484</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2025 Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan</dc:rights>
</oai_dc:dc>