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Preliminary Characterization of Protease Inhibitor from Bacteria-Associated with Sponge from Panggang Island, Seribu Islands

HAYATI Journal of Biosciences · Vol. 13 No. 2 (2009)

DOI
10.4308/hjb.13.2.58
ISSN
2086-4094, 1978-3019
Terbit
2009-12-02
Penerbit
Bogor Agricultural University, Indonesia
Bahasa
eng

Abstrak

Pathogenic bacteria produced protease that involved in molecular mechanism of foodborne disease. Produced protease involved in molecular mechanisms of foodborne diseases. The purpose of this research was to screen, identify and characterize the potential microorganisms associated with sponge as producer of protease inhibitor. Among 96 isolates examined, four isolates i.e 10A6, 6A3, 9A51, and 1A12 yielded protease inhibitors which were potential to inhibit protease substrates (40-90%). One of the most potential protease inhibitor producer, the bacteria isolate 6A3, was identified as Chromohalobacter sp. Chromohalobacter sp.6A3 produced protease inhibitor with optimum temperature and pH 300 C and 5, respectively. The inhibitor activity was stable when incubated at 400 C for ten minutes or at 300 C for 8 hours. Key words: Bacteria, Chromohalobacter sp., protease inhibitor, screen, sponge

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  • IPB University
  • Politeknik Negeri Pontianak
  • Soegijapranata Catholic University
  • Universitas Maritim Raja Ali Haji
  • Sriwijaya University
  • State University of Gorontalo
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Rekan penulisOrganisasiArtikel bersama
Tati NurhayatiIPB University20
Mala NurilmalaIPB University9
Nurjanah NurjanahIPB University8
Asadatun AbdullahIPB University7
Wini TrilaksaniIPB University6
DesniarIPB University5
Ella SalamahIPB University4
Asadatun AbdullahIPB University4
Pipih SuptijahIPB University4
Bustami IbrahimIPB University3
Untung Trimo LaksonoPoliteknik Negeri Pontianak3
Raden Hilman WirayudhaIPB University3
Ace BaehakiSriwijaya University3
Mala NurilmalaAfiliasi tidak diketahui3
Alberta Rika PratiwiSoegijapranata Catholic University2
Dahrul SyahIPB University2
Lily VirulyUniversitas Maritim Raja Ali Haji2
Nuri AndarwulanIPB University2
Desniar DesniarIPB University2
Bambang RiyantoIPB University2
Joko SantosoIPB University2
Silva FauziahIPB University2
Ruddy SuwandiIPB University2
Sugeng Heri SusenoIPB University2
Giri Rohmad BarokahIPB University2
Agoes Mardiono JacoebIPB University2
Shindy Hamidah ManteuIPB University2
Roni NugrahaAfiliasi tidak diketahui2
Roni NugrahaIPB University2
Rizsa Mustika PertiwiIPB University2
Uju UjuAfiliasi tidak diketahui2
Uju UjuIPB University2
Reinal PutalanState University of Gorontalo1
Safrina Dyah HardiningtyasIPB University1
Iriani SetyaningsihIPB University1
Rizfi Faris PariAfiliasi tidak diketahui1

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Sumber metadata: OAI-PMH (metadata jurnal) http://journal.ipb.ac.id/index.php/hayati/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">Preliminary Characterization of Protease Inhibitor from Bacteria-Associated with Sponge from Panggang Island, Seribu Islands</dc:title>
	<dc:creator xml:lang="en">NURHAYATI, TATI</dc:creator>
	<dc:creator xml:lang="en">SUHARTONO, MAGGY THENAWIDJAJA</dc:creator>
	<dc:creator xml:lang="en">NURAIDA, LILIS</dc:creator>
	<dc:creator xml:lang="en">POERWANTO, SRI BUDIARTI</dc:creator>
	<dc:description xml:lang="en">Pathogenic bacteria produced protease that involved in molecular mechanism of foodborne disease. Produced protease involved in molecular mechanisms of foodborne diseases. The purpose of this research was to screen, identify and characterize the potential microorganisms associated with sponge as producer of protease inhibitor. Among 96 isolates examined, four isolates i.e 10A6, 6A3, 9A51, and 1A12 yielded protease inhibitors which were potential to inhibit protease substrates (40-90%). One of the most potential protease inhibitor producer, the bacteria isolate 6A3, was identified as Chromohalobacter sp. Chromohalobacter sp.6A3 produced protease inhibitor with optimum temperature and pH 300 C and 5, respectively. The inhibitor activity was stable when incubated at 400 C for ten minutes or at 300 C for 8 hours. Key words: Bacteria, Chromohalobacter sp., protease inhibitor, screen, sponge </dc:description>
	<dc:publisher xml:lang="en">Bogor Agricultural University, Indonesia</dc:publisher>
	<dc:date>2009-12-02</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://journal.ipb.ac.id/hayati/article/view/207</dc:identifier>
	<dc:identifier>10.4308/hjb.13.2.58</dc:identifier>
	<dc:source xml:lang="en">HAYATI Journal of Biosciences; Vol. 13 No. 2 (2006): June 2006; 58</dc:source>
	<dc:source>2086-4094</dc:source>
	<dc:source>1978-3019</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://journal.ipb.ac.id/hayati/article/view/207/73</dc:relation>
</oai_dc:dc>