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Formulasi dan bioaktivitas suplemen tablet berbasis Spirulina dan hidrolisat kolagen kulit ikan nila

Jurnal Pengolahan Hasil Perikanan Indonesia · Vol. 22 No. 3 (2019) · hlm. 453–463

DOI
10.17844/jphpi.v22i3.28925
ISSN
2354-886X, 2303-2111
Terbit
2019-12-31
Penerbit
Department of Aquatic Product Technology IPB University in collaboration with Masyarakat Pengolahan Hasil Perikanan Indonesia (MPHPI)
Bahasa
eng

Abstrak

Spirulina is a microalga known as a superfood which contains high protein and is used in cosmetics, foods, and supplements industry. Collagen hydrolysate is the result of hydrolysis of collagen by protease. This study was aimed to determine the antioxidant activity and inhibition of tyrosynase from Spirulina, collagen hydrolysate and tablet formulated by combination of Spirulina and collagen hydrolysate. This research was conducted in three stages. The first stage was the extraction and hydrolysis of tilapia skin collagen, while the second stage was culturing and harvesting of Spirulina, and the third stage was determination of tablet formulation based on Spirulina and collagen hydrolysate followed by analysis of the antioxidant activity and inhibition of tyrosinase by selected tablet. Three formula with different ratio between Spirulina and collagen hydrolysates namely formula A (25%:53.75%), formula B (28.125%:50.625%), formula C (31.25%:47.5%) and additive such as vitamin C (12.5%), talk (1.25%), magnesium stearate (0.625%), aerosil (1.875%), avicel (5%) were developed. The result showed that formula A was the selected formula meeting the requirements of Ministry of Health based on the physical characteristics. The antioxidant activity of tablet A was 843 ppm and the tyrosinase inhibition was 163.56 ppm.

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  • IPB University
  • University of Brawijaya
  • Bandung Institute of Technology
  • Universitas Airlangga
  • National Research and Innovation Agency
  • Yonsei University
  • Afiliasi tidak diketahui
  • Organisasi berbeda
  • Organisasi sama
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Rekan penulisOrganisasiArtikel bersama
Kustiariyah TarmanIPB University16
Bambang RiyantoIPB University11
‪Tati NurhayatiIPB University7
Safrina Dyah HardiningtyasIPB University6
Wahyu RamadhanIPB University6
Joko SantosoIPB University5
Uju UjuIPB University5
Desniar DesniarIPB University5
Mega SafithriIPB University4
Tati NurhayatiIPB University4
Sugeng Heri SusenoIPB University4
Joko SantosoIPB University3
Bambang RiyantoBandung Institute of Technology3
Bustami IbrahimIPB University3
Fahri SinulinggaIPB University3
. UjuAfiliasi tidak diketahui3
NurjanahAfiliasi tidak diketahui3
Wahyu RamadhanAfiliasi tidak diketahui3
Farel WidiarsyahIPB University2
Desy ArisandiUniversity of Brawijaya2
Silva FauziahIPB University2
DesniarIPB University2
Woro Hastuti SatyantiniUniversitas Airlangga2
Dita aguistina BarusIPB University2
Apon Zaenal MustopaNational Research and Innovation Agency2
Meydia MeydiaYonsei University2
Desniar DesniarAfiliasi tidak diketahui2
Cahyuning IsnainiIPB University2
Zacky Arivaie SantosaIPB University2
Ella SalamahIPB University2
Zacky Arivai SantosaeAfiliasi tidak diketahui1
Wahyu RamadhanIPB University1
Purnama ArafahIPB University1
Joko SantosoIPB University1
Luky AdriantoIPB University1
Tri WahyuningsihIPB University1
Rizfi Faris PariAfiliasi tidak diketahui1

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Sumber metadata: OAI-PMH (metadata jurnal) http://journal.ipb.ac.id/index.php/jphpi/oai, pertama di-harvest 9 Nov 2026, terakhir terlihat 9 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Formulasi dan bioaktivitas suplemen tablet berbasis Spirulina dan hidrolisat kolagen kulit ikan nila</dc:title>
	<dc:creator xml:lang="en">Ahmad, Mirza Gulam</dc:creator>
	<dc:creator xml:lang="en">Setyaningsih, Iriani</dc:creator>
	<dc:creator xml:lang="en">Trilaksani, Wini</dc:creator>
	<dc:subject xml:lang="en">antioxidants activity</dc:subject>
	<dc:subject xml:lang="en">tablets</dc:subject>
	<dc:subject xml:lang="en">tyrosinase inhibition.</dc:subject>
	<dc:description xml:lang="en">Spirulina is a microalga known as a superfood which contains high protein and is used in cosmetics, foods, and supplements industry. Collagen hydrolysate is the result of hydrolysis of collagen by protease. This study was aimed to determine the antioxidant activity and inhibition of tyrosynase from Spirulina, collagen hydrolysate and tablet formulated by combination of Spirulina and collagen hydrolysate. This research was conducted in three stages. The first stage was the extraction and hydrolysis of tilapia skin collagen, while the second stage was culturing and harvesting of Spirulina, and the third stage was determination of tablet formulation based on Spirulina and collagen hydrolysate followed by analysis of the antioxidant activity and inhibition of tyrosinase by selected tablet. Three formula with different ratio between Spirulina and collagen hydrolysates namely formula A (25%:53.75%), formula B (28.125%:50.625%), formula C (31.25%:47.5%) and additive such as vitamin C (12.5%), talk (1.25%), magnesium stearate (0.625%), aerosil (1.875%), avicel (5%) were developed. The result showed that formula A was the selected formula meeting the requirements of Ministry of Health based on the physical characteristics. The antioxidant activity of tablet A was 843 ppm and the tyrosinase inhibition was 163.56 ppm.</dc:description>
	<dc:publisher xml:lang="en">Department of Aquatic Product Technology IPB University in collaboration with Masyarakat Pengolahan Hasil Perikanan Indonesia (MPHPI)</dc:publisher>
	<dc:date>2019-12-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.ipb.ac.id/jphpi/article/view/28925</dc:identifier>
	<dc:identifier>10.17844/jphpi.v22i3.28925</dc:identifier>
	<dc:source xml:lang="id">Jurnal Pengolahan Hasil Perikanan Indonesia; Vol 22 No 3 (2019): Jurnal Pengolahan Hasil Perikanan Indonesia; 453-463</dc:source>
	<dc:source xml:lang="en">Jurnal Pengolahan Hasil Perikanan Indonesia; Vol. 22 No. 3 (2019): Jurnal Pengolahan Hasil Perikanan Indonesia; 453-463</dc:source>
	<dc:source>2354-886X</dc:source>
	<dc:source>2303-2111</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journal.ipb.ac.id/jphpi/article/view/28925/18258</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2019 Mirza Gulam Ahmad, Iriani Setyaningsih, Wini Trilaksani</dc:rights>
</oai_dc:dc>