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Optimization of Hand Sanitizer Formulation with the Addition of Lemongrass (Cymbopogon citratus (DC.) Stapf) Essential Oil and a Combination of Essential Oils of Local Indonesian Empon-empon

Molekul: Jurnal Ilmiah Kimia · Vol. 19 No. 2 (2024) · hlm. 269–280

DOI
10.20884/1.jm.2024.19.2.10186
ISSN
2503-0310, 1907-9761
Terbit
2024-07-18
Penerbit
Universitas Jenderal Soedirman
Bahasa
eng

Abstrak

ABSTRACT: This research aimed to optimize the formulation of hand sanitizer by incorporating lemongrass (Cymbopogon citratus (DC.) Stapf) essential oil in combination with essential oils of local Indonesian empon-empon: temu giring (Curcuma heyneana Val. & van Zipj.), temu kunci (Kaempferia pandurata Roxb.), and temu mangga (Curcuma amada Roxb.). The optimization of hand sanitizer formulation was done based on several tests. The first was organoleptic test by observing the aroma, color, and form; the second was pH, homogeneity, and spreadability testing, and; the third was testing the antibacterial activities of each hand sanitizer formula against Escherichia coli ATCC 25922 and Staphylococcus aureus ATCC 25922. The research stages encompassed isolation of essential oils, formulation and evaluation of hand sanitizers, antibacterial activities test, optimization of hand sanitizer formulation, and identification of the chemical compounds in the hand sanitizer with the optimum formulation using the GC-MS method. The study resulted in the hand sanitizer with the optimum formulation containing the essential oils of lemongrass (3%) and temu giring (3%), demonstrating very strong antibacterial bioactivities against both E. coli ATCC 25922 and S. aureus ATCC 25923, with inhibition zones measuring 29.70 mm and 60.08 mm, respectively. This hand sanitizer had a distinctive aroma, combining the scents of lemongrass and temu giring. It was in liquid form, clear, and homogeneous, with pH and spreadibility values of 5.4 and 6.4 cm, respectively. The quality complied with SNI quality standards No. 06-2588. The primary active ingredients were E-citral (22.10%), Z-citral (17.88%), and 1,8-cineol (17.63%). Keywords: Essential oil, hand sanitizer, lemongrass, temu giring, temu kunci, temu mangga.

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  • Sebelas Maret University
  • Indonesia University of Education
  • State University of Malang
  • Universitas Jambi
  • State University of Jakarta
  • State University of Semarang
  • Universitas Islam Negeri Ar-Raniry
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Rekan penulisOrganisasiArtikel bersama
Widiastuti Agustina Eko SetyowatiSebelas Maret University4
Wiji WijiIndonesia University of Education3
Elfi Susanti VH1Afiliasi tidak diketahui3
Sri MulyaniSebelas Maret University3
Arumsasi Putri NugrahaniSebelas Maret University3
Karima MajidSebelas Maret University3
Aufa Vib MitsalinaSebelas Maret University2
Sulistyo SaputroSebelas Maret University1
Murwani Dewi WijayantiSebelas Maret University1
Sentot Budi RahardjoSebelas Maret University1
Liliasari LiliasariIndonesia University of Education1
E. Nursa'adahAfiliasi tidak diketahui1
Muhammad Nurul HanaIndonesia University of Education1
Hayuni Retno WidartiState University of Malang1
Ana PermanasariState University of Malang1
Dian SavitriState University of Semarang1
Ninuk LustyantieState University of Jakarta1
Predy SiswantoSebelas Maret University1
Sukarmin SukarminSebelas Maret University1
Rina MarianiUniversitas Jambi1
Nurlinawati NurlinawatiUniversitas Jambi1
NurlinawatiAfiliasi tidak diketahui1
Chusnur RahmiUniversitas Islam Negeri Ar-Raniry1
Tuszie WidhiyantiIndonesia University of Education1
Galuh YulianiIndonesia University of Education1
Jihan Assyifa FatihahIndonesia University of Education1
Tatik LestariSebelas Maret University1
Endang SusilowatiSebelas Maret University1
Khoirur Rohmaniatush SholihahSebelas Maret University1
Ifah MunifahNational Research and Innovation Agency1
Tyas Dwi RohmatunSebelas Maret University1
Nadia Indri SafitriSebelas Maret University1
Nova Dwi LestariSebelas Maret University1

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Sumber metadata: OAI-PMH (metadata jurnal) https://jos.unsoed.ac.id/index.php/jm/oai, pertama di-harvest 9 Nov 2026, terakhir terlihat 9 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en-US"> Optimization of Hand Sanitizer Formulation with the Addition of Lemongrass (Cymbopogon citratus (DC.) Stapf) Essential Oil and a Combination of Essential Oils of Local Indonesian Empon-empon</dc:title>
	<dc:creator>Ariani, Sri Retno Dwi</dc:creator>
	<dc:creator>Van Hayus, Elfi Susanti</dc:creator>
	<dc:creator>Mulyani, Sri</dc:creator>
	<dc:creator>Utomo, Suryadi Budi</dc:creator>
	<dc:creator>Wathon, Muhammad Hizbul</dc:creator>
	<dc:creator>Bilhaq, Natiq</dc:creator>
	<dc:creator>Pramesti, Anastasia Diaz</dc:creator>
	<dc:description xml:lang="en-US">ABSTRACT: This research aimed to optimize the formulation of hand sanitizer by incorporating lemongrass (Cymbopogon citratus (DC.) Stapf) essential oil in combination with essential oils of local Indonesian empon-empon: temu giring (Curcuma heyneana Val. &amp;amp; van Zipj.), temu kunci (Kaempferia pandurata Roxb.), and temu mangga (Curcuma amada Roxb.). The optimization of hand sanitizer formulation was done based on several tests. The first was organoleptic test by observing the aroma, color, and form; the second was pH, homogeneity, and spreadability testing, and; the third was testing the antibacterial activities of each hand sanitizer formula against Escherichia coli ATCC 25922 and Staphylococcus aureus ATCC 25922. The research stages encompassed isolation of essential oils, formulation and evaluation of hand sanitizers, antibacterial activities test, optimization of hand sanitizer formulation, and identification of the chemical compounds in the hand sanitizer with the optimum formulation using the GC-MS method. The study resulted in the hand sanitizer with the optimum formulation containing the essential oils of lemongrass (3%) and temu giring (3%), demonstrating very strong antibacterial bioactivities against both E. coli ATCC 25922 and S. aureus ATCC 25923, with inhibition zones measuring 29.70 mm and 60.08 mm, respectively. This hand sanitizer had a distinctive aroma, combining the scents of lemongrass and temu giring. It was in liquid form, clear, and homogeneous, with pH and spreadibility values of 5.4 and 6.4 cm, respectively. The quality complied with SNI quality standards No. 06-2588. The primary active ingredients were E-citral (22.10%), Z-citral (17.88%), and 1,8-cineol (17.63%).
&amp;nbsp;
Keywords: Essential oil, hand sanitizer, lemongrass, temu giring, temu kunci, temu mangga.</dc:description>
	<dc:publisher xml:lang="en-US">Universitas Jenderal Soedirman</dc:publisher>
	<dc:date>2024-07-18</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://jos.unsoed.ac.id/index.php/jm/article/view/10186</dc:identifier>
	<dc:identifier>10.20884/1.jm.2024.19.2.10186</dc:identifier>
	<dc:source xml:lang="en-US">Molekul; Vol 19 No 2 (2024); 269-280</dc:source>
	<dc:source>2503-0310</dc:source>
	<dc:source>1907-9761</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://jos.unsoed.ac.id/index.php/jm/article/view/10186/5529</dc:relation>
</oai_dc:dc>